An 11-year-old boy presented with erythematous plaques over the bilateral mandibular and mental regions for 2 years, accompanied by cough and dyspnea for more than 2 months. Chest computed tomography angiography revealed marked stenosis of the right pulmonary artery, irregular aortic caliber, and aortic wall thickening. Histopathological examination of the skin lesion, including immunohistochemistry and special stains, confirmed a chronic suppurative inflammation. Whole-exome sequencing was negative. A final diagnosis of granuloma faciale and Takayasu arteritis was established. Combination therapy with systemic tocilizumab, prednisone, and methotrexate, along with topical 0.1% tacrolimus ointment, resulted in a favorable clinical response. This report summarizes the clinical features of a pediatric case of granuloma faciale and Takayasu arteritis and reviews the etiology, diagnostic approach, and current treatment strategies for the disorders, aiming to enhance clinicians' understanding of these conditions.
Humans ; Male ; Child ; Takayasu Arteritis/diagnosis* ; Facial Dermatoses/diagnosis*

No abstract available.
Dermatitis, Perioral ; Ivermectin

Eyelid Diseases ; diagnosis ; immunology ; pathology ; Facial Dermatoses ; diagnosis ; immunology ; pathology ; HIV Infections ; complications ; immunology ; Humans ; Immunocompromised Host ; Male ; Middle Aged ; Molluscum Contagiosum ; complications ; diagnosis ; immunology ; pathology

Facial Dermatoses ; diagnosis ; pathology ; Humans ; Male ; Pyoderma Gangrenosum ; diagnosis ; pathology ; Sweet Syndrome ; diagnosis ; pathology ; Young Adult

No abstract available.
Carcinoma, Basal Cell ; Facial Dermatoses* ; Keratosis, Actinic ; Skin*

No abstract available.
Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/blood/*complications/diagnosis/drug therapy/physiopathology ; Biological Markers/blood ; Drug Therapy, Combination ; Facial Dermatoses/complications/diagnosis ; Female ; Hand Joints/physiopathology/radiography ; Humans ; Immunosuppressive Agents/therapeutic use ; Inflammation Mediators/blood ; Knee Joint/physiopathology/radiography ; Lupus Erythematosus, Systemic/blood/*complications/diagnosis/drug therapy ; Middle Aged ; Syndrome ; Treatment Outcome

Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Dermatitis* ; Dermatitis, Perioral ; Humans ; Metronidazole ; Mouth ; Nose ; Tacrolimus

Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Dermatitis* ; Dermatitis, Perioral ; Humans ; Metronidazole ; Mouth ; Nose ; Tacrolimus

OBJECTIVETo observe the clinical effect of micro-plasma radio frequency treatment of facial post-burn hyperpigmentation.

METHODSFrom June 2012 to August 2013, a total of 25 cases with facial post-burn hyperpigmentation were treated with micro-plasma treatment for 3-5 times. The roller tip was used with setting of 60-90 watts and 3-4 passes were performed in different directions. Treatments were repeated at an interval of 8 weeks.

RESULTSAll patients tolerated the pain. After treatment, the facial hyperpigmentation improved. Complete recovery was achieved in 4 cases; significant improvement in 11 cases; moderate in 7 cases and no effect in 3 cases. No hyperpigmentation, depigmentation and scar formation was observed.

CONCLUSIONMicro-plasma radio frequency treatment is an ideal treatment for post-burn hyperpigmentation with lower side effect.

Aged ; Burns ; complications ; Cicatrix ; Facial Dermatoses ; etiology ; therapy ; Facial Injuries ; complications ; Humans ; Hyperpigmentation ; etiology ; therapy ; Pulsed Radiofrequency Treatment ; instrumentation ; methods

BACKGROUND: Periocular dermatitis (PD) is a common condition and can be classified as either allergic or non-allergic. Because the periocular region is one of the most sensitive areas of the skin, contact with any environmental or therapeutic allergen may give rise to dermatitis. OBJECTIVE: The aim of this study was to investigate the clinical usefulness of patch testing to determine sensitivity to contact allergens in PD patients. METHODS: Patch testing was conducted in 29 PD patients using the T.R.U.E. test(R) at Pusan National University Hospital. We examined the results of patch testing, the probable cause of PD, and the history of use of ophthalmic medication. RESULTS: Contact hypersensitivity was detected using the T.R.U.E. test(R) in 62.1% (18/29) of the patients, and contact hypersensitivity to specific ophthalmic medications was observed in 33.3% (3/9) of the patients with a history of using ophthalmic medication. CONCLUSION: We suggest that patch testing can be utilized to elucidate the relevant contact allergen in patients with PD. Patch testing with specific ophthalmic medications is valuable to determine allergic reactions in patients who have used ophthalmic medications.
Allergens* ; Busan ; Dermatitis ; Dermatitis, Contact ; Dermatitis, Perioral* ; Humans ; Hypersensitivity ; Patch Tests* ; Skin