This study investigated the clinical characteristics and kidney outcomes of childhood-onset lupus nephritis (LN), and risk factors associated with prognosis. Methods: We enrolled 216 patients with histologically diagnosed LN during childhood. The Korean Society of Pediatric Nephrology organized a retrospective cohort study of childhood-onset LN in 13 major pediatric nephrology centers in South Korea. Results: The mean age at kidney biopsy was 13.2 ± 3.22 years. The main forms of presentation were nephrotic syndrome and/or hematuria in 152 patients (70.4%), and the most common histological finding was World Health Organization (WHO) class IV in 138 patients (63.9%), followed by WHO class III in 34 patients (15.7%). In the outcome analysis, the mean follow-up period of the patients was 7.8 ± 5.11 years. At last follow-up, 32 patients (14.8%) developed advanced chronic kidney disease (CKD). Male sex and failure to achieve remission at 12 months of treatment were significant risk factors for developing advanced CKD (hazard ratio of 2.57 and 2.29, respectively). Conclusion: Our study demonstrated the clinical characteristics and long-term outcomes of patients with childhood-onset LN. Male sex and failure to achieve remission in the first year of treatment were predictive of advanced CKD. Therefore, prompt awareness and close monitoring of these high-risk patients are needed, which may further improve the prognosis of children with LN.

Purpose: The aim was to conduct a three-dimensional comparison of impacted canines with their contralateral normal counterparts in patients exhibiting unilateral buccal impaction of the maxillary canine, utilizing the palatal plane as the benchmark reference. Materials and Methods: Computed tomography scans from a cohort of 31 patients diagnosed with unilateral buccal impaction of the maxillary canine were analyzed. The impacted canine was examined against the contralateral normal canine, focusing on the variables of rotation, torque, angulation, root length, and root volume. The disparities in these parameters between the left and right canines and their association with patient age were evaluated. Results: Notable differences were observed in rotation, angulation, torque, root length, and root volume when comparing the impacted canine to its contralateral normal counterpart.Furthermore, a significant positive correlation was identified between the age of the patients and the root length discrepancy of the impacted and contralateral normal canines. Conclusion The palatal plane proves to be a viable skeletal reference for predicting the impaction of maxillary canines, with rotation, angulation, and torque serving as reliable indicators. The study further elucidates that the unilateral buccally impacted maxillary canine is characterized by a discernibly shorter root length and diminished root volume in comparison to the contralateral normal canine.

Purpose: The aim was to conduct a three-dimensional comparison of impacted canines with their contralateral normal counterparts in patients exhibiting unilateral buccal impaction of the maxillary canine, utilizing the palatal plane as the benchmark reference. Materials and Methods: Computed tomography scans from a cohort of 31 patients diagnosed with unilateral buccal impaction of the maxillary canine were analyzed. The impacted canine was examined against the contralateral normal canine, focusing on the variables of rotation, torque, angulation, root length, and root volume. The disparities in these parameters between the left and right canines and their association with patient age were evaluated. Results: Notable differences were observed in rotation, angulation, torque, root length, and root volume when comparing the impacted canine to its contralateral normal counterpart.Furthermore, a significant positive correlation was identified between the age of the patients and the root length discrepancy of the impacted and contralateral normal canines. Conclusion The palatal plane proves to be a viable skeletal reference for predicting the impaction of maxillary canines, with rotation, angulation, and torque serving as reliable indicators. The study further elucidates that the unilateral buccally impacted maxillary canine is characterized by a discernibly shorter root length and diminished root volume in comparison to the contralateral normal canine.

Purpose: The aim was to conduct a three-dimensional comparison of impacted canines with their contralateral normal counterparts in patients exhibiting unilateral buccal impaction of the maxillary canine, utilizing the palatal plane as the benchmark reference. Materials and Methods: Computed tomography scans from a cohort of 31 patients diagnosed with unilateral buccal impaction of the maxillary canine were analyzed. The impacted canine was examined against the contralateral normal canine, focusing on the variables of rotation, torque, angulation, root length, and root volume. The disparities in these parameters between the left and right canines and their association with patient age were evaluated. Results: Notable differences were observed in rotation, angulation, torque, root length, and root volume when comparing the impacted canine to its contralateral normal counterpart.Furthermore, a significant positive correlation was identified between the age of the patients and the root length discrepancy of the impacted and contralateral normal canines. Conclusion The palatal plane proves to be a viable skeletal reference for predicting the impaction of maxillary canines, with rotation, angulation, and torque serving as reliable indicators. The study further elucidates that the unilateral buccally impacted maxillary canine is characterized by a discernibly shorter root length and diminished root volume in comparison to the contralateral normal canine.