Normal values and upper limits (95th percentile and 95% confidence interval of liver, spleen and portal vein size, as well as liver extensions below the costal margin were determined prospectively with ultrasound in 224 healthy subjects (renal donors). Correlation with sex, age, weight, height, and body surface area were assessed. Some correlation values were significant (r ? 0.30). The highest correlation (r=0.65 was liver AP diameter with weight. A formula to predict normal liver AP diameter was derived. Another set of subjects with established liver disease was compared with the normal means. All abnormal diameter means were at or above the 95th percentile, and the difference between the means of the normal and abnormal diameters were significant.

Human ; Male ; Female ; Middle Aged ; Adult ; Young Adult ; Adolescent ; Liver ; Spleen ; Portal Vein ; Adult ; Veins ; Palpation ; Percussion ; Radiography

Background and Objectives: Occult hepatitis B virus infection is defined as the presence hepatitis Bvirus DNA (HBV DNA) in the serum or tissues of persons who have negative test for hepatitis B surface antigen(HBsAg). It is believed that transmission of hepatitis B infection from blood and organ donations negativefor HBsAg is due to HBV occult infection. The aim of this study was to determine the prevalence of occulthepatitis B infection and the level of viremia among these individuals with occult infection.Methods: Data on hepatitis B profile, HBV-DNA titer and alanine aminotransferase (ALT) levels of 398subjects enlisted for donor nephrectomy from June 2006 to June 2008 at the National Kidney and TransplantInstitute (NKTI) were reviewed.Results: One hundred twenty five of the 398 subjects (31.4%) included in the study were positivefor anti-HBc; 12/125 (9.6%) has detectable serum HBV DNA levels. Antibody to hepatitis surface antigen (anti-HBs) was detected in 8/12 (66.7%) of the HBV-DNA positives. ALT levels in seven of the subjects (58.3%)with occult hepatitis B were normal.Conclusion: There is high prevalence rate (9.6%) of occult hepatitis B infection among kidney donors atthe NKTI. Patients with occult hepatitis B infection have low viremia (
Anti-hbc ; Hbsag ; Hepatitis B Virus ; Prevalence