Relationship of oocyte diameter and risk factors, embryo development during IVF treatment Introduction: We aimed to determine whether the simple non-invasive measurement of oocyte size using a time-lapse system and assess the impact on occurrence of fertilization and embryo quality in assisted reproduction cycles. Materials and methods: A retrospective study was performed on 70 infertile patients who underwent the first IVF cycle at Mon-CL hospital. A total of 70 cycles which yielded 483 metaphase II oocytes were included in the analysis. In addition, we evaluated age, body mass index, ovarian reserve markers, fertilization and good embryo rate. The results were processed using SPSS 21.0. Results: The patients’s age ranged from 22 to 45 years (34.94±4.89 on average). The mean oocyte cytoplasmic diameter was 115.35±5.19 µm, total diameter was 167.61±9.61 µm, zona pellucida thickness was 21.58±4.09. There was no statistically significant association between oocyte size and the occurrence of fertilization or the qualitative embryo classification on day 3. Age, body mass index, cause of infertility, and ovarian response did not affect oocyte sizes.

BACKGROUND. In the world, infertility occurs in 10-15% of the total couples and male infertility accounts for 40-50% of the infertile cases. Infertility frequency in Mongolia is 8.7% in 2003 and 11.6% in 2013. According to the Child and Maternity hospital study, 25.6% of infertility is due to men. Microdeletions of the Y chromosome long arm are the most common molecular genetic causes of severe infertility in men. They affect three regions including azoospermia factors (AZFa, AZFb and AZFc), which contain various genes involved in spermatogenesis. OBJECTIVES. The aim of the present study is to investigate the relationship between sexual hormones and AZF microdeletion on Y chromosome in Mongolian infertile men with azoospermia and severe oligozoospermia. MATERIAL AND METHODS. Through a cross sectional study, 50 infertile men were examined for Y chromosome microdeletions from January 2018 to August 2018. We determined hormone level, testis biopsy and microdeletions of the Y chromosome using six loci of 3 regions of the AZF gene were investigated by multiplex polymerase chain reaction. Semen analysis was performed on samples obtained by self-masturbation at the hospital after 2-7 days of sexual abstinence. Reproductive hormone level in serum including total testosterone, follicular stimulating hormone (FSH), and LH is measured at time 8 am to 11 am. If sperm is not recovered, testicular biopsy was performed on the patient. All collected datas were evaluated with Statistical Package for Social Sciences (SPSS, version 22.0). RESULTS. The rate of microdeletion was 4.0% (2 out of 50 patients). The deletion was on AZFa in the first patient, AZFc in the second patient. The patients with Y chromosome microdeletion had azoospermia. AZFa deleted patient has sertoli cell only syndrome in testis biopsy with FSH 58.0 mIU/ml, LH 12.0 mIU/ml, total testosterone 5.0 ng/ml. AZFc deleted patient had FSH 23.85 mIU/ml, LH 13.01 mIU/ml, total testosterone 4.06 ng/ml. Serum FSH and LH levels were significantly higher in Y chromosome deleted group and FSH level was significantly lower in sperm-retrieved group on TESE. СONCLUSION. We determined 2 cases of Y chromosome microdeletion (4.0%) in infertile men. Serum FSH and LH levels were significantly higher in Y chromosome deleted group.

BACKGROUND: Nowadays, in economy of Mongolia there are a lot of mining, construction, transportation and powerplant sectors with high risk, top rate of industrial accidents and occupational disease. Moreover, it’sbeen seen that noise, vibration and dust effect on worker’s health have a huge negative effects inthose sector’s workplaces.GOAL: Based on occupational condition assessment between 2010-2014 of Occupational condition andmonitoring department of Occupational Health Research Center, noise, vibration and general dustwere measured at workplace of mining, construction and power plant sectors.MATERIAL AND METHODS: Some issues of occupational hygiene were cross sectional studies. Based on archive of OHRC,information has been collected by fact methods. The results have been processed statistically onSPSS-17 statistic program and have been compared with relevant standards and normative.RESULTS: From 740 workplaces at 89 enterprises in 3 sectors, in 686 noises level has been measured. Theaverage level of noise measurements has been above the maximum allowed amount standards. Thehighest results were in sector of mining and construction.At total of 166 workplaces, the average vibration level was also above of maximum allowed amount.And also the highest results were seen in sector of mining.At total of 447 workplaces, the average general dust level was 3-5 times more than maximum allowedamount and the highest results were seen I sector of mining and construction.From some measurements of occupational hygiene at workplaces that attended in this study, generaldust amounts and vibration levels are straight low related and have a statistical importance.CONCLUTIONS:The amount of general vibration, noise and general dust in this research at sectors of construction,mining and power plant were higher than the standard of allowed amounts.

Background During the last ten years cardiovascular disease has became one of the priority cause of death in Selenge province, while 23.9 cases in 10.000 population. Studying cause of increasing cardiovascular disease by year and year, connecting with arterial hypertension control and influenced factors is our research work background.GoalTo determine uncontrolled arterial hypertension and evaluate its influenced factors among the population with arterial hypertension in Selenge province.Objectives:1. Research uncontrolled arterial hypertension among the population2. Determine factors that influence uncontrolled arterial hypertensionMaterials and Metods: Research model: Population based moment model of analitic research is used to survey control of population with arterial hypertension. Research coverage and Sampling: Eruu, Zuunburen, and Khutul soums were chosen from 23 soums including center of Selenge province through the random sampling. And then 480 people with arterial hypertension, aged above 18 years were participated in the research. Data was analysed by SPSS 17 program. Collecting information method: Situation of arterial hypertension control is taken by questionnaire method developed by collaboration with WHO and International Association of Arterial Hypertension, and whether follow the drug treatment instruction of physicians is evaluated by MMAS questionnaire method developed by Association of Control Case Managment of America. Arterial hypertension, weight and height of participants were measured. Although people with arterial hypertension under 140-90 mm.Hy are reported “people who are controlling their arterial pressure in normal rate”.ResultsTotally 480 people with arterial hypertension, aged above 18 years were chosen from of Eruu, Zuunburen, and Khutul soums and center of Selenge province. Approximetly, 29.1 percent were male, 70.8 percent were female and average age was 52.43. About 34 percent were high education, 85.8 percent were married and 34.4 percent were retired people. According to the survey, 68 people or 14.1 percent were controlled their arterial pressure/hypertension in normal rate, 412 people or 85.8 percent were uncontrolled their arterial pressure/hypertension in normal rate. Because of the arterial hypertension 59 percent of the participants were under control of physicians. Also there was difference on age and gender with statistical benefit. (p=0.001) People who can control arterial pressure in normal rate were 12.7 percent of people under control of physicians.Conclusions:About 85.8 percent or 412 people with arterial hypertension were uncontrolled, 90 percent were male and 84.1 percent were female. Because of the arterial hypertension, 59 percent of the participants were under control of physicians. But 87.3 percent of them cannot control their arterial pressure/ypertension in normal rate. Physicians control, employment, body mass index and following drug treatment instruction were the factors influence on arterial hypertension control.