1.Comparative Analysis of Clinic pathological Characteristics in Patients Undergoing Liver Resection
Unenbat G ; Enkhtsatsral B ; Bayart-Uils B ; Ariyaboleg O ; Tsersendorj D ; Amgalantuul B ; Batsaikhan B ; Munkdelger B ; Yerbolat A ; Munkhzaya Ch ; Lkham N ; Chinburen J ; Monkhtsetseg J ; Gantuya D
Mongolian Journal of Health Sciences 2025;90(6):147-151
Background:
Hepatocellular carcinoma (HCC) remains one of the leading causes of cancer-related mortality worldwide
and in Mongolia. Alcohol-related liver disease (ALD) and metabolic dysfunction-associated steatohepatitis (MASH) are
two major etiological factors contributing to the rising burden of HCC, each presenting distinct clinical and pathological
characteristics.
Aim:
To compare the clinical, pathological, and survival characteristics of patients with ALD-related HCC and MASH-related HCC who underwent liver resection.
Material and Methods:
A retrospective cohort study was conducted using clinical and pathological data from 980 patients who underwent liver resection between 2010 and 2024. Among them, 191 were categorized into the ALD group and
789 into the MASH group. Clinical parameters, laboratory findings, tumor pathology (size, grade, fibrosis stage, vascular
invasion), recurrence, and overall survival (OS) were analyzed. A simulated Kaplan–Meier survival curve was generated
based on group-level survival estimates.
Results:
Patients with ALD were significantly younger and predominantly male compared with those in the MASH group
(p=0.0014; p<0.0001). The MASH group demonstrated more aggressive pathological features, including larger tumors
(>5 cm), poorer differentiation (G3–4), advanced T4 stage, and a higher rate of large-vessel invasion (all p<0.05). Despite
these findings, the MASH group showed a longer mean overall survival (92.6 months) than the ALD group (82.0 months;
p=0.0206).
Conclusion
Although MASH exhibits more aggressive pathological features compared with ALD, patients in the MASH
group demonstrated better overall survival. These findings underscore the importance of incorporating etiological differences into the diagnostic, therapeutic, and postoperative management strategies for HCC.
2.Radicular cyst associated with a primary second molar
Innovation 2018;12(4):50-
Radicular cysts are the most common inflammatory cysts and arise from the epithelial residues in the periodontal ligament as a result of periapical periodontitis following death and necrosis of the pulp. They are usually encountered in association with permanent teeth. However, occurrence in relation to deciduous teeth seems to be very rare.
In this case, we presents treatment of radicular cyst associated with mandibular primary second molar following pulp therapy and discusses the relationship between pulp therapy and the growth of the cyst. The treatment consisted of decompression of the cyst sac, extraction of the involved primary tooth and 6 months follow up of the patient.
Our purpose of the study was to evaluate the bone formation after the decompression and describe the benefit of this conservative surgical treatment.
Case Report: A 7 years old girl, radiographic examination showed a large, circular, well-defined unilocular radiolucent area on the left mandible and impacted #34 and #35 which had incomplete roots and open apices. Signs of root resorption were evident in the adjacent teeth. Under local anesthesia, mandibular primary left first (#74) and second molars (#75) were extracted and decompression of the cyst was performed. A tissue sample was also taken for the biopsy.
Conclusion: The follow-up was performed periodically under radiographic examinations and after 6 months the impacted teeth were at the position and new bone formation was evident at the former cyst site. This surgical technique preferred in young patients to promote the bone formation and encourage the eruption of permanent teeth.
Result Analysis
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