Background: According to the Health Indicators 2023, diseases of the genitourinary system have ranked fourth among the causes of diseases of the population over the past 10 years, accounting for 10.2% of all diseases. The incidence of genitourinary tract infections by age group compared with 2014 increased by 997 cases in 2023 for all ages, and the highest increase by 2455.9 cases in those over 65 years of age. Therefore, early detection, diagnosis, and prevention of kidney disease are important. Material and method: The study included 40 adult persons who were hospitalized with chronic kidney disease at Sindura-med hospital in 2023-2024. We studied the clinical observation in chronic kidney disease using the pulse palpation, point palpation method of traditional medicine, and Pasternatsky’s symptom palpation of Western medicine. Result: At Sindura-med hospital, all patients diagnosed with chronic kidney disease had cold character pulse reading symptoms and pain on the kidney points of traditional medicine. Eye swelling is a common symptom in chronic kidney disease, but 17,5 percent of the study participants experienced eye swelling.
The majority, 52.5% of all inpatients, and 57.1% of women inpatients had on both sides plus Pasternatsky’s sign, which is a painful sensation when palpating the kidney area, but 45.5% of men inpatients had positive Pasternatsky sign on the right side. Conclusion According to traditional medical theory, when a disease has been going on for a long time, a cold pulse will be detected through pulse reading diagnosis. In kidney disease, a positive Pasteur’s sign, which is pain felt on palpation in the area, is a key diagnostic indicator.

Purpose: To study effect of San Gen talkh medicine and San Gen granule medicine, on healthy rats immune system Method: In this study 32 male healthy Wistar rats were randomly divided into normal group, low dose group of San Gen talkh (SGTLD), high dose group of San gen talkh (SGTHD) and group of San Gen granule (SGG). In normal group rats were administrated 0.2m l/kg saline solution, in San gen talkh groups rats with low dose and high dose were administrated 0.85g/kg, 1.70g/kg San Gen talkh respectively and in San gen granule medicine groups rats 1.3 g/kg San gen granule medicine, once daily for 42 day. By Elisa method measured IL-10, IL-12, IL-17, IFN-γ and TGF-β in blood plasma and spleen tissue of rat. Result: In this experimental result, there was no significantly difference all measured cytokine of blood plasm (P>0.05) between healthy group and all medicine group. In spleen tissue, there was significantly increased IFN-γ (P<0.05) and TGF-β (P<0.05) in SGTHD group and was significantly increased IFN-γ (PO.05), IL-10 (P<0.01)and TGF-β (PO.001) in SGG group compared with normal group. Conclusion High doses San Gen talkh medicine and San Gen granule medicine can support cellular immune system, humoral immune system on healthy rats.