Objectives: In Canada, non-communicable diseases account for 88% of all deaths, most of which could be prevented through a healthier diet, regular physical activity (PA), smoking cessation, and reduced alcohol consumption. This study aims to estimate the number of deaths that could be prevented or delayed if (1) the average behaviors of Canadians aligned with recommendations for healthy behaviors, or if (2) the average behaviors of Canadians equaled those of residents in the provinces with the healthiest behaviors. Methods: We used the Preventable Risk Integrated Model macrosimulation model to estimate the number of deaths that could be prevented through population-level behavioral changes. Information on Canadians’ health behaviors was obtained from the most recent edition of the Canadian Community Health Survey (2015), which reported diet (from 20 487 participants) as well as PA, alcohol consumption, smoking, and sedentary time (from 110 095 participants). Age-specific and gender-specific mortality data for 2015 were obtained from Canadian Vital Statistics, and 95% uncertainty intervals (UI) were calculated through Monte Carlo analyses. Results: Following behavioral recommendations could have prevented 30 756 deaths (95% UI, 25 867 to 34 965) in 2015. Improving Canadians’ lifestyles to match the behaviors of the healthiest provinces could have prevented 6758 deaths (95% UI, 5062 to 8382). Improvements in fruit and vegetable intake alone could have prevented most of these deaths. Most preventable deaths were attributed to cardiovascular diseases. Conclusions These findings show that even modest, realistic lifestyle improvements at the population level could substantially reduce the burden of chronic disease in Canada.

Methods: We assessed baseline neutral upright, standing flexion, seated lateral radiographs, and magnetic resonance imaging (MRI) for patients identified with spondylolisthesis from January 2021 to May 2022 by a single spine surgeon. DS was classified by Meyerding and Clinical and Radiographic Degenerative Spondylolisthesis classifications. A difference of >10° or >8% between views, respectively, was used to characterize angular and translational instability. Analysis of variance and paired chi-square tests were utilized to compare modalities. Results: A total of 136 patients were included. Seated lateral and standing flexion radiographs showed the greatest slip percentage (16.0% and 16.7%), while MRI revealed the lowest (12.2%, p <0.001). Standing flexion and lateral radiographs when seated produced more kyphosis (4.66° and 4.97°, respectively) than neutral upright and MRI (7.19° and 7.20°, p <0.001). Seated lateral performed similarly to standing flexion in detecting all measurement parameters and categorizing DS (all p >0.05). Translational instability was shown to be more prevalent when associated with seated lateral or standing flexion than when combined with neutral upright (31.5% vs. 20.2%, p =0.041; and 28.1% vs. 14.6%, p =0.014, respectively). There were no differences between seated lateral or standing flexion in the detection of instability (all p >0.20). Conclusions Seated lateral radiographs are appropriate alternatives for standing flexion radiographs. Films taken when standing up straight do not offer any more information for DS detection. Rather than standing flexion-extension radiographs, instability can be detected using an MRI, which is often performed preoperatively, paired with a single seated lateral radiograph.

Methods: All patients aged >18 years who underwent primary one- to four-level ACDF at a single institution were retrospectively identified. Propensity matching was performed to compare patients’ PEEK or titanium alloy cages with structural allograft. Multivariate logistic regression analysis was performed to measure the effect of interbody spacer composition on the likelihood of pseudarthrosis development. Results: Of the 502 patients who received structural allograft and had 1-year postoperative dynamic radiographs, 96 patients were propensity matched to 32 patients who received a PEEK cage, and 162 patients were propensity matched to 54 patients who received a titanium alloy cage. Multivariate logistic regression analysis identified that PEEK cage implants (odds ratio [OR], 3.34; p =0.007) predicted pseudarthrosis development compared with structural allograft implantation. Titanium alloy cage (OR, 1.64; p =0.156) implantation was not predictive of pseudarthrosis. One-year postoperative PROMs were not significantly different between patients who received PEEK or titanium alloy cages and those who received structural allograft (all p >0.05). Conclusions Compared with structural allograft, receiving a PEEK cage increased the risk of pseudarthrosis development following ACDF, whereas receiving a titanium alloy cage had no significant effect on pseudarthrosis development. One-year postoperative patient-reported outcomes were similar between patients who received structural allograft, PEEK, and titanium alloy interbody spacers.