1.Probucol combined with tirofiban for angina pectoris in patients with coronary heart disease after interventional surgery
Alatenqimuge ; Wangliang ZHU ; Bo YU ; Jianfei LI ; Xin QIAO ; Mingzhe SONG ; Dongye YUN
Journal of Interventional Radiology 2025;34(6):579-583
Objective To discuss the effect of probucol combined with tirofiban treatment on serum lipid peroxide levels and vascular endothelial function in patients with angina pectoris after interventional surgery of coronary heart disease(CHD).Methods A total of 120 patients with angina pectoris occurring after interventional surgery from January 2018 to December 2022 at the People's Hospital of Inner Mongolia Autonomous Region of China were enrolled in this study.Using random digital table method,the patients were divided into observation group(n=60)and control group(n=60).The patients of the control group received tirofiban,while the patients of the observation group received tirofiban plus probucol.All the preoperative and postoperative 7-day relevant indicators were recorded.The main observation indicator was the overall effective rate,and the secondary observation indicators included the frequency and duration of angina attacks,Seattle Angina Questionnaire(SAQ)score,cardiac function,myocardial injury markers,serum lipid peroxide levels,endothelial function and adverse reactions.Results The total effective rate in the observation group was 91.67%(55/60),which was higher than 78.33%(47/60)in the control group,the difference was statistically significant(P<0.05).After treatment,the improvement degree of angina pectoris,SAQ score,LVEF,serum superoxide dismutase(SOD),nitric oxide(NO)in the observation group were higher than those in the control group,while the LVESD,LVEDD,serum creatine kinase isozyme(CK-MB),lactate dehydrogenase(LDH),creatine kinase(CK),malondialdehyde(MDA),endothelin-1(ET-1)in the observation group were lower than those in the control group,the differences in the above indexes were statistically significant(all P<0.05).Conclusion For patients with angina pectoris occurring after interventional surgery of CHD,probucol combined with tirofiban has exact efficacy,which can promote the recovery of cardiac function,reduce myocardial injury,regulate serum lipid peroxide levels,and improve vascular endothelial function.
2.Virtual endoscopy evaluation of congenital aural atresia.
Dongye CHEN ; Xiaowei CHEN ; Yun WANG ; Zhengyu JIN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2007;21(7):318-320
OBJECTIVE:
To value the virtual endoscopic visualization for preoperative assessment of congenital aural atresia.
METHOD:
Twenty patients with congenital aural atresia underwent a high-resolution CT of the temporal bone with VE, 8 patients subsequently underwent congenital aural atresiaplasty. CT examinations of the temporal bone were carried out using spiral equipment and endoscopic 3D processing was carried out on a separate workstation equipped with a flying through program.
RESULT:
VE is valuable for the evaluation of stapes, malleus-incus complex, facial nerve (only the tympanic portion), incus-stapes joint, round window niche, middle er space, the VE assessment matches the operation exploration perfectly, coincidence rates were 87. 5%, 100%, 100%,75%, 100% and 100% respectively.
CONCLUSION
This image processing method can be used pre-operatively for assessment, the individual planning, and simulation.
Adolescent
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Child
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Child, Preschool
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Ear Canal
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abnormalities
;
surgery
;
Endoscopy
;
Female
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Humans
;
Image Processing, Computer-Assisted
;
Male
;
User-Computer Interface
;
Young Adult

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