1.Evaluating the Influence of Scan Timing on Dosimetric Accuracy in EBT3 and EBT4 Radiochromic Films
Jin Dong CHO ; Su Chul HAN ; Jason Joon Bock LEE ; Hyebin LEE ; Heerim NAM
Progress in Medical Physics 2024;35(4):135-144
Purpose:
This study compares the dosimetric properties of EBT3 and EBT4 GAFchromic films in transmission and reflection scanning modes, focusing on dose response, sensitivity, and postirradiation stability.
Methods:
The EBT3 and EBT4 films were irradiated at doses of 0–10 Gy using a Varian TrueBeam linear accelerator at 6 MV. The films were scanned at intervals between 1 and 336 hours after irradiation in both transmission and reflection modes. Net optical density (NetOD) values from each scan were used to evaluate dose response and sensitivity, with calibration curves created for each film and scan mode. Dose differences between calculated and delivered doses were assessed over time.
Results:
The EBT3 and EBT4 films exhibited similar dose–response curves and stable NetOD values across both scanning modes. However, EBT4 exhibited reduced sensitivity variability in response to dose changes. After irradiation, NetOD values increased up to 24 hours before stabilizing, suggesting that a 24-hour scan time is sufficient for consistent measurements. Dose differences between films and modes remained within ±4%.
Conclusions
EBT4 offers comparable dosimetric performance to EBT3, with additional benefits, such as improved dose–response linearity and reduced sensitivity fluctuations. The findings indicate that EBT4 can serve as a reliable successor to EBT3.
2.Postoperative Thoracic Cord Compression Induced by a Dural Sealant System (DuraSeal®): A Case Report and Literature Review
Dong Soon JANG ; Seung Hun SHEEN ; Inbo HAN ; Soo Hyun LEE ; Woo Seok CHOI ; Minsung BOCK ; Seil SOHN
The Nerve 2024;10(1):57-62
Cerebrospinal fluid (CSF) leakage is a rare complication that can occur due to dural defects during spinal surgery, hindering the improvement of the surgical site and increasing the possibility of infection. DuraSeal® is a dural sealing adhesive that prevents CSF leakage and is used as an adjunct to enable the watertight repair of dural defects when the dura is damaged during spinal surgery. In the present case, DuraSeal® was applied to repair a dural defect in the surgical area after thoracic spine surgery, and no neurological problems occurred immediately after surgery. However, a day later, the patient’s paraparesis worsened; therefore, reoperation was performed and the symptoms improved.
3.Evaluating the Influence of Scan Timing on Dosimetric Accuracy in EBT3 and EBT4 Radiochromic Films
Jin Dong CHO ; Su Chul HAN ; Jason Joon Bock LEE ; Hyebin LEE ; Heerim NAM
Progress in Medical Physics 2024;35(4):135-144
Purpose:
This study compares the dosimetric properties of EBT3 and EBT4 GAFchromic films in transmission and reflection scanning modes, focusing on dose response, sensitivity, and postirradiation stability.
Methods:
The EBT3 and EBT4 films were irradiated at doses of 0–10 Gy using a Varian TrueBeam linear accelerator at 6 MV. The films were scanned at intervals between 1 and 336 hours after irradiation in both transmission and reflection modes. Net optical density (NetOD) values from each scan were used to evaluate dose response and sensitivity, with calibration curves created for each film and scan mode. Dose differences between calculated and delivered doses were assessed over time.
Results:
The EBT3 and EBT4 films exhibited similar dose–response curves and stable NetOD values across both scanning modes. However, EBT4 exhibited reduced sensitivity variability in response to dose changes. After irradiation, NetOD values increased up to 24 hours before stabilizing, suggesting that a 24-hour scan time is sufficient for consistent measurements. Dose differences between films and modes remained within ±4%.
Conclusions
EBT4 offers comparable dosimetric performance to EBT3, with additional benefits, such as improved dose–response linearity and reduced sensitivity fluctuations. The findings indicate that EBT4 can serve as a reliable successor to EBT3.
4.Evaluating the Influence of Scan Timing on Dosimetric Accuracy in EBT3 and EBT4 Radiochromic Films
Jin Dong CHO ; Su Chul HAN ; Jason Joon Bock LEE ; Hyebin LEE ; Heerim NAM
Progress in Medical Physics 2024;35(4):135-144
Purpose:
This study compares the dosimetric properties of EBT3 and EBT4 GAFchromic films in transmission and reflection scanning modes, focusing on dose response, sensitivity, and postirradiation stability.
Methods:
The EBT3 and EBT4 films were irradiated at doses of 0–10 Gy using a Varian TrueBeam linear accelerator at 6 MV. The films were scanned at intervals between 1 and 336 hours after irradiation in both transmission and reflection modes. Net optical density (NetOD) values from each scan were used to evaluate dose response and sensitivity, with calibration curves created for each film and scan mode. Dose differences between calculated and delivered doses were assessed over time.
Results:
The EBT3 and EBT4 films exhibited similar dose–response curves and stable NetOD values across both scanning modes. However, EBT4 exhibited reduced sensitivity variability in response to dose changes. After irradiation, NetOD values increased up to 24 hours before stabilizing, suggesting that a 24-hour scan time is sufficient for consistent measurements. Dose differences between films and modes remained within ±4%.
Conclusions
EBT4 offers comparable dosimetric performance to EBT3, with additional benefits, such as improved dose–response linearity and reduced sensitivity fluctuations. The findings indicate that EBT4 can serve as a reliable successor to EBT3.
5.Evaluating the Influence of Scan Timing on Dosimetric Accuracy in EBT3 and EBT4 Radiochromic Films
Jin Dong CHO ; Su Chul HAN ; Jason Joon Bock LEE ; Hyebin LEE ; Heerim NAM
Progress in Medical Physics 2024;35(4):135-144
Purpose:
This study compares the dosimetric properties of EBT3 and EBT4 GAFchromic films in transmission and reflection scanning modes, focusing on dose response, sensitivity, and postirradiation stability.
Methods:
The EBT3 and EBT4 films were irradiated at doses of 0–10 Gy using a Varian TrueBeam linear accelerator at 6 MV. The films were scanned at intervals between 1 and 336 hours after irradiation in both transmission and reflection modes. Net optical density (NetOD) values from each scan were used to evaluate dose response and sensitivity, with calibration curves created for each film and scan mode. Dose differences between calculated and delivered doses were assessed over time.
Results:
The EBT3 and EBT4 films exhibited similar dose–response curves and stable NetOD values across both scanning modes. However, EBT4 exhibited reduced sensitivity variability in response to dose changes. After irradiation, NetOD values increased up to 24 hours before stabilizing, suggesting that a 24-hour scan time is sufficient for consistent measurements. Dose differences between films and modes remained within ±4%.
Conclusions
EBT4 offers comparable dosimetric performance to EBT3, with additional benefits, such as improved dose–response linearity and reduced sensitivity fluctuations. The findings indicate that EBT4 can serve as a reliable successor to EBT3.
6.Evaluating the Influence of Scan Timing on Dosimetric Accuracy in EBT3 and EBT4 Radiochromic Films
Jin Dong CHO ; Su Chul HAN ; Jason Joon Bock LEE ; Hyebin LEE ; Heerim NAM
Progress in Medical Physics 2024;35(4):135-144
Purpose:
This study compares the dosimetric properties of EBT3 and EBT4 GAFchromic films in transmission and reflection scanning modes, focusing on dose response, sensitivity, and postirradiation stability.
Methods:
The EBT3 and EBT4 films were irradiated at doses of 0–10 Gy using a Varian TrueBeam linear accelerator at 6 MV. The films were scanned at intervals between 1 and 336 hours after irradiation in both transmission and reflection modes. Net optical density (NetOD) values from each scan were used to evaluate dose response and sensitivity, with calibration curves created for each film and scan mode. Dose differences between calculated and delivered doses were assessed over time.
Results:
The EBT3 and EBT4 films exhibited similar dose–response curves and stable NetOD values across both scanning modes. However, EBT4 exhibited reduced sensitivity variability in response to dose changes. After irradiation, NetOD values increased up to 24 hours before stabilizing, suggesting that a 24-hour scan time is sufficient for consistent measurements. Dose differences between films and modes remained within ±4%.
Conclusions
EBT4 offers comparable dosimetric performance to EBT3, with additional benefits, such as improved dose–response linearity and reduced sensitivity fluctuations. The findings indicate that EBT4 can serve as a reliable successor to EBT3.
7.Cholecystectomy for Prevention of Recurrence after Endoscopic Clearance of Bile Duct Stones in Korea.
Myung Eun SONG ; Moon Jae CHUNG ; Dong Jun LEE ; Tak Geun OH ; Jeong Youp PARK ; Seungmin BANG ; Seung Woo PARK ; Si Young SONG ; Jae Bock CHUNG
Yonsei Medical Journal 2016;57(1):132-137
PURPOSE: Cholecystectomy in patients with an intact gallbladder after endoscopic removal of stones from the common bile duct (CBD) remains controversial. We conducted a case-control study to determine the risk of recurrent CBD stones and the benefit of cholecystectomy for prevention of recurrence after endoscopic removal of stones from the CBD in Korean patients. MATERIALS AND METHODS: A total of 317 patients who underwent endoscopic CBD stone extraction between 2006 and 2012 were included. Possible risk factors for the recurrence of CBD stones including previous cholecystectomy history, bile duct diameter, stone size, number of stones, stone composition, and the presence of a periampullary diverticulum were analyzed. RESULTS: The mean duration of follow-up after CBD stone extraction was 25.4+/-22.0 months. A CBD diameter of 15 mm or larger [odds ratio (OR), 1.930; 95% confidence interval (CI), 1.098 to 3.391; p=0.022] and the presence of a periampullary diverticulum (OR, 1.859; 95% CI, 1.014 to 3.408; p=0.045) were independent predictive factors for CBD stone recurrence. Seventeen patients (26.6%) in the recurrence group underwent elective cholecystectomy soon after endoscopic extraction of CBD stones, compared to 88 (34.8%) in the non-recurrence group; the difference was not statistically significant (p=0.212). CONCLUSION: A CBD diameter of 15 mm or larger and the presence of a periampullary diverticulum were found to be potential predictive factors for recurrence after endoscopic extraction of CBD stones. Elective cholecystectomy after clearance of CBD stones did not reduce the incidence of recurrent CBD stones in Korean patients.
Adult
;
Aged
;
Bile Duct Diseases/*diagnosis/epidemiology/surgery
;
Case-Control Studies
;
Cholangiopancreatography, Endoscopic Retrograde
;
Cholecystectomy/*methods
;
Common Bile Duct/*pathology/radiography
;
Elective Surgical Procedures
;
Female
;
Gallstones/epidemiology/*surgery
;
Humans
;
Incidence
;
Male
;
Middle Aged
;
Recurrence
;
Republic of Korea/epidemiology
;
Risk Factors
;
*Sphincterotomy, Endoscopic
8.A Case of Alveolar Adenoma Involving Multiple Lung Nodules.
Dong Seok LEE ; Min Sik HWANG ; Jae Min LIM ; Mi Hye KIM ; Bock Hyun JUNG ; Gil Hyun KANG ; Dong Kon YOO
Korean Journal of Medicine 2014;86(5):623-626
Alveolar adenoma is a very rare benign intraparenchymal lung tumor originating from type II pneumocytes. It can be mistaken for other benign tumors or lung cancer in radiological images. It is especially difficult to distinguish alveolar adenoma from sclerosing hemangioma. A small aspiration biopsy specimen, such as with percutaneous needle aspiration, is insufficient for a pathological diagnosis. Surgical resection is the only method by which a pathological diagnosis can be made and the disease treated. An alveolar adenoma presenting as multiple nodules is very rare and has to our knowledge not been reported in Korea previously. Here, we report a case of alveolar adenoma in multiple nodules in a 57-year-old female and review the literature.
Adenoma*
;
Biopsy, Needle
;
Diagnosis
;
Female
;
Histiocytoma, Benign Fibrous
;
Humans
;
Korea
;
Lung Neoplasms
;
Lung*
;
Middle Aged
;
Needles
;
Pneumocytes
9.Acute Mercury Vapor Inhalation Toxicity after Burning Charms: A Case Report.
Hong Yeul LEE ; Gyoung Hoon KANG ; Ki Ho NAM ; Mi Hye KIM ; Bock Hyun JUNG ; Hui Dong KANG ; Se Hyun OH ; Jaemin LIM
The Korean Journal of Critical Care Medicine 2010;25(3):182-185
Cinnabar is the mineral with mercury in combination with sulfur, and it has been used to make charms in China and Korea. If cinnabar is overheated, mercury vapor that is extremely hazardous or sometimes fatal can be released. We experienced 5 patients of a family who were exposed to mercury vapor when they burnt charms. One of them developed severe acute respiratory failure and the patient needed mechanical ventilation and extracorporeal membrane oxygenation (ECMO). Despite treatment with cortiocosteroid, D-penicillamine, ECMO and plasmapheresis, the radiologic findings of a patient worsened and he died.
Burns
;
China
;
Extracorporeal Membrane Oxygenation
;
Humans
;
Inhalation
;
Korea
;
Mercury Compounds
;
Penicillamine
;
Plasmapheresis
;
Respiration, Artificial
;
Respiratory Insufficiency
;
Sulfur
10.Advanced Surface Reconstruction Technique to Build Detailed Surface Models of the Liver and Neighboring Structures from the Visible Korean Human.
Dong Sun SHIN ; Min Suk CHUNG ; Jun Won LEE ; Jin Seo PARK ; Jinoh CHUNG ; Seung Bock LEE ; Sang Ho LEE
Journal of Korean Medical Science 2009;24(3):375-383
Unlike volume models, surface models, which are empty three-dimensional images, have small file size, so that they can be displayed, rotated, and modified in a real time. For the reason, the surface models of liver and neighboring structures can be effectively applied to virtual hepatic segmentectomy, virtual laparoscopic cholecystectomy, and so on. The purpose of this research is to present surface models of detailed structures inside and outside the liver, which promote medical simulation systems. Forty-seven chosen structures were liver structures such as portal triad, hepatic vein, and neighboring structures such as the stomach, duodenum, muscles, bones, and skin. The structures were outlined in the serially sectioned images from the Visible Korean Human to prepare segmented images. From the segmented images, serial outlines of each structure were stacked; on the popular commercial software, advanced surface reconstruction technique was applied to build surface model of the structure. A surface model of the liver was divided into eight models of hepatic segments according to distribution of the portal vein. The surface models will be distributed to encourage researchers to develop the various kinds of medical simulation of the abdomen.
Asian Continental Ancestry Group
;
Computer Simulation
;
Humans
;
*Image Processing, Computer-Assisted
;
Imaging, Three-Dimensional
;
Liver/*anatomy & histology
;
*Models, Anatomic
;
Models, Biological
;
Portal Vein/anatomy & histology
;
Software
;
Tomography, X-Ray Computed

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