This paper aims to summarize Professor ZHOU Shaohua's clinical experience in treating Parkinson's disease （PD） based on the "disease-symptom-syndrome integration" approach. It is believed that kidney essence deficiency is the root cause of the disease， and phlegm-stasis accumulating toxin is the key factor for its deterioration. PD could be divided into the prodromal stage， early stage and middle-late stage. In the prodromal stage， treatment focuses on tonifying the kidney and replenishing marrow， choosing Zuogui Pill （左归丸） or Yougui Pill （右归丸） to prescribe with modifications according to accompanying non-motor symptoms such as constipation and rapid eye movement sleep behavior disorder. For the early stage， the disease is differentiated into three syndromes， liver-kidney yin deficiency with stirring wind， spleen-kidney yang deficiency， and excessive phlegm turbidity， then following the principle of "calming wind by regulating blood first"， the basic prescriptions of Dading Fengzhu Pill （大定风珠）， Yougui Pill （右归丸） and Jinshui Liujun Decoction （金水六君煎） are applied respectively， combined with Siwu Decoction （四物汤） to nourish blood and extinguish wind. For the middle-late stage， therapies of tonifying the kidney and conso-lidating original qi are combined with detoxifying and resolving turbidity， prescribing fleshy and nourishing medicinals such as deer-horn glue （Cervus nippon Temminck） and turtle shell glue （Colla Carapacis et Plastri Testudinis）， together with Huanglian Jiedu Decoction （黄连解毒汤） to clear heat， detoxify and resolve turbidity， implementing simultaneous tonification and elimination. Integrated traditional Chinese and western medicine intervention is emphasized for non-motor symptoms including orthostatic hypotension and dysphagia.

Objective: To synthesize the collagen-GAG template and to evaluate its feasibility to be used as the MSCs vehicle for meniscal tissue engineering. Methods: The collagen-GAG template was synthesized from rat tail type Ⅰ collagen and GAG using Yannas method. Then the post-stimulated MSCs by bFGF and TGF-β1 were added in. The MSCs-enriched collagen sponges were cultured in vitro， two weeks later the histological and ultrastructure detection was performed. Results: The histological and ultrastructure of the collagen-GAG template remained intact after 2 weeks' culture, and the MSCs in it remained viable. Conclusion: The collagen-GAG template synthesized in this experiment is suitable for the meniscal tissue engineering reconstruction as the vehicle for MSCs seed cells.

Objective: To observe the decompressive effect of laminectomy on the spinal cord compressed anteriorly in the cervical spine. Methods : The compression of the cervical spinal cord-meningeal complex was simulated using a small transducer pushed into the spinal canal in 7 whole cadaver spines. The depth of canal occlusion was controlled depending on 20%, 30% and 40% of the saggital diameter of the canal. The distribution and the change of the stress on the spinal cord-meningeal complex and the displacement of dural sac were recorded before and after laminectomy. Results: When the anterior transducer was pushed into the spinal canal with 40% occlusion, the force was 3.86 kPa on the anterior wall and 0.38 kPa on the posterior wall of the spinal cord-meningeal complex respectively. After extensive laminectomy, the anterior compressive force decreased 6.06% - 14.38% and the displacement of the posterior dura wall was 0.44 mm. Conclusions: The anterior compressive force was mainly absorbed by the anterior part of the spinal cord-meningeal complex. Extensive laminectomy had no significant decompressive effect on the spinal cord compressed anteriorly inthecervical spine.