1.Recent advance in clinical researches of computed tomography in pancreas transplantation
Dichen TANG ; Jiali FANG ; Zheng CHEN
Chinese Journal of Organ Transplantation 2025;46(9):670-676
Pancreas transplantation can achieve effective blood glucose control and delay, or even reverse, the progression of diabetic complications, making it the most effective surgical treatment for diabetes. The success of the procedure depends on precise preoperative assessment, accurate intraoperative techniques, and strict postoperative monitoring. Computed tomography (CT) enables rapid acquisition of high-resolution tissue images and has important clinical value in both the preoperative assessment and postoperative monitoring of pancreas transplantation. This article reviews the application of CT in pancreas transplantation and its derivative technologies, with the aim of providing references for the clinical application and further research of imaging techniques in this field.
2.Recent advance in clinical researches of computed tomography in pancreas transplantation
Dichen TANG ; Jiali FANG ; Zheng CHEN
Chinese Journal of Organ Transplantation 2025;46(9):670-676
Pancreas transplantation can achieve effective blood glucose control and delay, or even reverse, the progression of diabetic complications, making it the most effective surgical treatment for diabetes. The success of the procedure depends on precise preoperative assessment, accurate intraoperative techniques, and strict postoperative monitoring. Computed tomography (CT) enables rapid acquisition of high-resolution tissue images and has important clinical value in both the preoperative assessment and postoperative monitoring of pancreas transplantation. This article reviews the application of CT in pancreas transplantation and its derivative technologies, with the aim of providing references for the clinical application and further research of imaging techniques in this field.
3.Design of Three-Dimensional Printed Diabetic Insoles with Gradient Modulus
Siyao ZHU ; Dichen LI ; Lei TANG ; Changning SUN ; Jianfeng KANG ; Hongmou ZHAO ; Yan ZHANG ; Ling WANG
Journal of Medical Biomechanics 2021;36(1):E102-E109
Objective To propose a quick and low-cost personalized diabetic foot modeling and insole design scheme, so as to reduce the plantar pressure accurately. Methods The foot model of the patient was constructed by scaling the model with foot feature parameters, to make biomechanical analysis on plantar pressure. By means of numerical mapping model of insole elasticity and plantar pressure, the three-dimensional (3D) personalized insole model with gradient modulus was constructed. The insole was then manufactured via 3D printing technology and used for experimental validation. Results The related mechanical parameters from finite element prediction of the foot model constructed by the scaling modeling method were close to those of the CT reconstructed model, and the maximum error was controlled within 15%. Compared with wearing the normal insole, the peak pressure of the personalized insole was effectively reduced by 20%. The time and economic cost of this simplified design was reduced by approximately 90%. Conclusions The design scheme of the diabetes insole shortens the design cycle, and the personalized insole can effectively and accurately reduce the sole pressure, and reduce the risk of foot ulcer, which provides a technical basis for the promotion of the personalized diabetes insole.
4.Total knee arthroplasty based on the assistance of three-dimensional-printing personalized surgical navigation template
Bing QIU ; Mingjiao ZHANG ; Bensen TANG ; Biyong DENG ; Dichen LI ; Fei LIU
Chinese Journal of Tissue Engineering Research 2015;(48):7731-7735
BACKGROUND:With significantly individual differences in the anatomy of the knee joint, traditional total knee replacement is difficult to accurately predict the position of locating limb alignment, size of the prosthesis and osteotomy amount of patients during operation. OBJECTIVE:To investigate the clinical effect of total knee replacement based on the assistance of medical image reconstruction, computer-aided design technology and 3D-printing personalized surgical navigation template. METHODS:Medical image data of patients were col ected using CT or magnetic resonance scanning equipment. The three-dimensional reconstruction of the bone was conducted by two-dimensional medical image processing technology. The navigation template was designed by computer-aided design technology. The personalized surgical navigation templates were produced by 3D printing technology, and the clinical total knee replacement was conducted. The postoperative results were evaluated using imageology. RESULTS AND CONCLUSION:Arigin 3D Pro (Arigin Medical Co., Ltd.) can accurately reconstruct a three-dimensional model of the lower limb bones. The three-dimensional design software Arigin Surgical Templating by their independent research and development can precisely pinpoint related lower limb axis, including limb alignment, rotation axis of the femur and osteotomy reference point. The personalized navigation template we researched and produced for knee surgery fitted tightly with femoral condyle and tibial plateau bone anatomy during operation, without significant movement. The deviation of patients’ limb alignment was less than 3° after total knee replacement.

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