1.Research Progress on Dendrobii Officinalis Caulis as Medicinal and Edible Traditional Chinese Medicine
Yang HU ; Mian ZHAO ; Yuxuan QIU ; Debao YE ; Yangqing LIU ; Chaofeng ZHANG ; Haibo WANG ; Jian-Ming CHENG
Journal of Nanjing University of Traditional Chinese Medicine 2024;40(1):94-108
Tiepishihu(Dendrobii officinalis Caulis)is a medicinal and food source herbal medicine with the effect of benefiting stomach and promoting fluid,nourishing Yin and clearing heat.It has rich chemical components and pharmacological activities,with anti-inflammatory,anti-bacterial,anti-oxidation,anti-tumor,immunomodulatory,blood press regulation,hypoglycemic effects.It is not only used as medicinal food and health care products,but also widely used in medicine,such as Shihu Yeguang Wan,Compound fresh dendrobium granules and other drugs,with high medicinal and economic value.This paper summarized the resource distribution,chemical composition,pharmacological activities,and medicine and food of Dendrobii officinalis Caulis,and analyzed its application status,laying a theoretical foundation for the sustainable development,medicinal and food homologous development and comprehensive utilization of Dendrobii officinalis Caulis.
2.Excitability of facial nerve motor nucleus in patients with hemifacial spasm
Debao YANG ; Shijun ZHOU ; Zhimin WANG
Chinese Journal of Neuromedicine 2021;20(6):617-620
Objective:To study whether the excitability of facial nerve motor nucleus is increased in patients with facial spasm to further study the mechanism of facial spasm.Methods:Thirty patients with HFS underwent MVD in our hospital from April 2018 and March 2019 were chosen in our study. The amplitude and threshold voltage of facial nerve motor evoked potential (FNMEP) of the affected side and healthy side were monitored and compared by using monopulse stimulation and multi-pulse stimulation. The changes of FNMEP amplitude in patients before and after sevoflurane inhalation were monitored.Results:Stable facial motor evoked potential could be stimulated by monopulse in 26 patients (89.7%) on the affected side, while only 5 patients (17.2%) on the healthy side, showing statistical difference between the two sides ( P<0.05); there was no significant difference in FNMEP amplitude between the affected side and the healthy side ([207.2±62.1] μV vs. [180.2±55.0] μV, P>0.05); the average threshold voltage of neuromotor evoked potential on the affected side was (140.3±26.8) V, which was significantly lower than that in the healthy side ([177.0±23.2] V, P<0.05). The amplitude of FNMEP on the affected side was (207.2±62.1) μV, (133.0±36.5) μV, and (70.4±40.2) μV, respectively, before sevoflurane inhalation, and at 0.5 fold of minimun alveolar concentration (MAC) and 1.0 fold of MAC concentrations, with significant differences ( P<0.05). Conclusion:In patients with hemifacial spasm, there is increased excitability of facial nerve motor nucleus on the affected side, which to a certain extent supports the central theory of hemifacial spasm pathogenesis.
3.Nerve combing for trigeminal neuralgia without vascular compression
Debao YANG ; Shijun ZHOU ; Zhimin WANG
Chinese Journal of Neuromedicine 2018;17(1):95-98
Objective To evaluate the efficacy and safety of nerve combing for trigeminal neuralgia without neurovascular decompression.Methods A retrospective review of clinical data of 281 patients with trigeminal neuralgia,admitted to our hospital from January 2008 to January 2016,was performed.The patients were divided into two groups:patients from group A were treated by nerve combing (n=32),and patients from group B were treated by microvascular decompression (n=249).The two groups were compared in terms of surgical outcomes and postoperative complications.Results The pain was completely relieved in 90.6% patients of group A (29/32) and 94.4% patients of group B (235/249),respectively;the mean follow-up duration was 62.5 months in group A,and 78.1% patients (25/32) were completely relieved;the mean follow-up duration was 59.8 months in group B,and 84.1% patients (201/239)were completely relieved;no statistically significant differences existed in the surgical outcomes and long-term outcomes between the two groups (P>0.05).No complications related to severe disability or death were noted in the two groups.The rate of facial numbness in patients from group A (71.9%) was significant higher than that in group B (2.5%,P<0.05).Conclusions Nerve combing is a safe and effective treatment for trigeminal neuralgia without neurovascular decompression.Most patients treated with nerve combing experienced some degrees of facial numbness.
4.Clinic significance of allergen serum immunoglobulin E detection for the flying personnel with allergic rhinitis
Xuhui TAI ; Kai LI ; Yongxin LIAN ; Xiaohui ZHANG ; Xiuming WANG ; Debao LIU ; Xin YANG ; Yanling CHU ; Qiang XUE
Chinese Journal of Aerospace Medicine 2017;28(4):272-276
Objective To study the clinic significance of allergen serum immunoglobulin E (IgE) detection for the flying personnel with allergic rhinitis.Methods One hundred and twentyeight flying personnel with clinically suspected allergic rhinitis were drawn 2 ml venous blood.Serum tIgE (total IgE) and 14 allergen sIgE (specific IgE) including 7 aspiration allergens and 7 food allergens were detected with antibody kit.Strong positive reaction rates of the flying personnel with aspiration allergens and food allergens were compared as well as the correlation of serum tIgE and positive reaction rate of allergen sIgE was analyzed.Results Positive reaction rate of tIgE in 128 flying personnel with allergic rhinitis was 85.9 % (110/128) and positive reaction rate of sIgE was 91.4% (117/128).The top 3 positive reaction rates of aspiration allergens were dust mite (66.4%),tree combination (32.8%) and house dust (23.4%).The top 3 positive reaction rates of food allergens were fruit combination (mango/pineapple/apple/peach/strawberry) (18.0%),seafood combination (shrimp/crab/scallop) (16.4%) and fish combination (ling/trout/weever) (13.3%).Positive response rate of the flying personnel with both aspiration and food allergens was 12.5 % (16/128).The aspiration allergens mainly reflected as strong positive reaction while the food allergens mainly expressed as weakly positive reaction.The strong positive reaction showed significance between aspiration and food allergens.(x2=16.881,P<0.05).The strong positive reaction of allergen serum had the positive correlation to tIgE value (r=0.517,P<0.01).Conclusions The allergen serum IgE detection have shown its objective,accurate and noninvasive advantages and are with less age,disease,medication,manipulation and other external limitations.The test results can be quantitatively or semi-quantitatively expressed and can determine tIgE level within the detection.So it has certain clinical significance on diagnosis,treatment,evaluation and prevention for the flying personnel with allergic rhinitis.
5.Clinic significance of allergen serum immunoglobulin E detection for the flying personnel with allergic rhinitis
Xuhui TAI ; Kai LI ; Yongxin LIAN ; Xiaohui ZHANG ; Xiuming WANG ; Debao LIU ; Xin YANG ; Yanling CHU ; Qiang XUE
Chinese Journal of Aerospace Medicine 2017;28(4):272-276
Objective To study the clinic significance of allergen serum immunoglobulin E (IgE) detection for the flying personnel with allergic rhinitis.Methods One hundred and twentyeight flying personnel with clinically suspected allergic rhinitis were drawn 2 ml venous blood.Serum tIgE (total IgE) and 14 allergen sIgE (specific IgE) including 7 aspiration allergens and 7 food allergens were detected with antibody kit.Strong positive reaction rates of the flying personnel with aspiration allergens and food allergens were compared as well as the correlation of serum tIgE and positive reaction rate of allergen sIgE was analyzed.Results Positive reaction rate of tIgE in 128 flying personnel with allergic rhinitis was 85.9 % (110/128) and positive reaction rate of sIgE was 91.4% (117/128).The top 3 positive reaction rates of aspiration allergens were dust mite (66.4%),tree combination (32.8%) and house dust (23.4%).The top 3 positive reaction rates of food allergens were fruit combination (mango/pineapple/apple/peach/strawberry) (18.0%),seafood combination (shrimp/crab/scallop) (16.4%) and fish combination (ling/trout/weever) (13.3%).Positive response rate of the flying personnel with both aspiration and food allergens was 12.5 % (16/128).The aspiration allergens mainly reflected as strong positive reaction while the food allergens mainly expressed as weakly positive reaction.The strong positive reaction showed significance between aspiration and food allergens.(x2=16.881,P<0.05).The strong positive reaction of allergen serum had the positive correlation to tIgE value (r=0.517,P<0.01).Conclusions The allergen serum IgE detection have shown its objective,accurate and noninvasive advantages and are with less age,disease,medication,manipulation and other external limitations.The test results can be quantitatively or semi-quantitatively expressed and can determine tIgE level within the detection.So it has certain clinical significance on diagnosis,treatment,evaluation and prevention for the flying personnel with allergic rhinitis.

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