1.Bibliometric analysis of randomized clinical trials in the Philippines.
Ian Theodore G. Cabaluna ; Sarah F. Sevilla ; Arianna Maever L. Amit ; Timothy Hudson David C. Carandang ; Adrian Espiritu ; Carol Stephanie C. Tan-Lim
Acta Medica Philippina 2026;60(4):7-14
BACKGROUND AND OBJECTIVE
Randomized controlled trials (RCTs) are essential for advancing evidence-based healthcare by evaluating the effectiveness and safety of health interventions. Despite the increasing recognition of clinical research, the Philippines has had limited contributions to global RCT output. This bibliometric analysis aims to assess the trends, characteristics, and impact of RCTs conducted in the Philippines and published online.
METHODSA systematic search of Medline (PubMed), and EMBASE, along with Acta Medica Philippina, was conducted to identify published RCTs from January 1990 to October 2022. Eligible studies were screened and analyzed based on publication trends, funding sources, study designs, research settings, and institutional contributions. Descriptive statistics were used to summarize key findings.
RESULTSA total of 391 RCTs were identified, with a notable increase in number of RCTs published over time. Most studies (91.8%) were published in international journals, and funding was primarily sourced from pharmaceutical companies (47.1%). The predominant RCT design was two-arm parallel (64.7%), with hospitals being the most common research setting (54.2%). Research areas were led by infectious diseases, particularly vaccine-preventable illnesses (23.8%). While the University of the Philippines Manila (21.1%) and the Research Institute for Tropical Medicine (13.7%) were the leading institutions in terms of highest number of published RCTs, foreign authors accounted for nearly half (47.3%) of primary authorships. The most cited studies focused on cardiovascular diseases, infectious diseases, and oncology.
CONCLUSIONThe increasing number of published RCTs in the Philippines reflects growth in research capacity and institutional engagement. Strengthening national research dissemination platforms and fostering regional collaborations will be essential in advancing the Philippines’ contribution to global clinical research.
Human ; Bibliometrics ; Bibliometric Analysis ; Philippines ; Publications
2.The perceptions of AI use of Filipino occupational therapy students at the University of Santo Tomas: A study protocol.
Kim Gerald MEDALLON ; Sandra Tan PASCUA ; Jian De Los SANTOS ; Bealin BELEY ; Danielle Marie MARISTELA ; Danielle Kristian Bjork SUI ; Luke Isaac MACAPUGAY
Philippine Journal of Allied Health Sciences 2026;9(2):29-33
OBJECTIVES
This study aims to explore the perceptions of UST Occupational Therapy students regarding AI chatbots in the context of school-related activities. It will further focus on their concerns, utility, and perceived effects of AI on learning related to school activities
METHODSA qualitative descriptive design will be used and will utilize three focus group discussions, one for each year level (first, second, and third-year students), to gather extensive and accurate accounts of students’ perceptions. Thematic analysis, using manual coding and following Braun and Clarke’s six-phase analytic framework, will be employed for data analysis.
RESULTSThe study is expected to generate themes describing students’ perceived usefulness, concerns, and learning-related impacts of AI, providing insights that may support the responsible and informed integration of AI in occupational therapy education.
Human ; Statistics As Topic ; Therapeutics ; Students ; Occupational Therapy ; Focus Groups
3.ONE (Onwards towards NCD rEduction) Cavite Project: A multisectoral educational approach to cardiovascular risk factor screening and management.
Deborah Ignacia ONA ; Alberto ATILANO ; Marilou ESPIRITU ; Rey-an Nino GARCIA ; Ardith TAN ; David Raymund SALVADOR
Philippine Journal of Cardiology 2026;54(1):77-83
Ischemic heart disease (IHD) remains the most common cause of death while cerebrovascular disease (CVD) is the third most common in the Philippines. IHD and CVD represent complications resulting from prevalent non-communicable diseases (NCDs) and risk factors which present important opportunities for primary and secondary prevention.
This study aimed to pilot a sustainable multisectoral approach for community-based screening and management of cardiovascular (CV) risk factors and determine the effects of a multisectoral collaboration approach on the rate of screening, prevalence and control rates for selected risk factors.
This is a quality improvement project that determines the baseline prevalence and control rates of CV risk factors followed by intense screening efforts with support from private partnerships. The project's core components are: (a) capacity building (b) information dissemination; (c) service provision; and (d) health monitoring. Rates of screening, prevalence and control were monitored over a two-year period.
A total of 94,125 patients were screened through the ONE Cavite Project over two years (January 2021 to December 2022). A total of 61,271 were newly identified as having hypertension (65.1%), 24,069 diagnosed with diabetes mellitus type 2 (25.6%), 29,257 diagnosed to have dyslipidemia (31.1%) and 13,204 smokers (14.0%) were identified.
Intensification of screening was successful in improving identification of individuals with NCDs. The impact of continued educational support for both providers and patients in this study reaffirmed its role as a central component of NCD diagnosis, management and prevention.
Hypertension ; Diabetes Mellitus ; Dyslipidemias ; Myocardial Ischemia ; Primary Prevention
4.ONE (Onwards towards NCD rEduction) Cavite Project: A multisectoral educational approach to cardiovascular risk factor screening and management.
Deborah Ignacia ONA ; Alberto ATILANO ; Marilou ESPIRITU ; Rey-an Nino GARCIA ; Ardith TAN ; David Raymund SALVADOR
Philippine Journal of Cardiology 2026;54(1):77-83
Ischemic heart disease (IHD) remains the most common cause of death while cerebrovascular disease (CVD) is the third most common in the Philippines. IHD and CVD represent complications resulting from prevalent non-communicable diseases (NCDs) and risk factors which present important opportunities for primary and secondary prevention.
This study aimed to pilot a sustainable multisectoral approach for community-based screening and management of cardiovascular (CV) risk factors and determine the effects of a multisectoral collaboration approach on the rate of screening, prevalence and control rates for selected risk factors.
This is a quality improvement project that determines the baseline prevalence and control rates of CV risk factors followed by intense screening efforts with support from private partnerships. The project's core components are: (a) capacity building (b) information dissemination; (c) service provision; and (d) health monitoring. Rates of screening, prevalence and control were monitored over a two-year period.
A total of 94,125 patients were screened through the ONE Cavite Project over two years (January 2021 to December 2022). A total of 61,271 were newly identified as having hypertension (65.1%), 24,069 diagnosed with diabetes mellitus type 2 (25.6%), 29,257 diagnosed to have dyslipidemia (31.1%) and 13,204 smokers (14.0%) were identified.
Intensification of screening was successful in improving identification of individuals with NCDs. The impact of continued educational support for both providers and patients in this study reaffirmed its role as a central component of NCD diagnosis, management and prevention.
Hypertension ; Diabetes Mellitus ; Dyslipidemias ; Myocardial Ischemia ; Primary Prevention
5.Effect of a brief training program on the knowledge of Filipino primary care providers in a rural and a remote setting: A before and after study
Julianne Keane M. Pascual ; Arianna Maever Loreche ; Regine Ynez H. De mesa ; Noleen Marie C. Fabian ; Josephine T. Sanchez ; Janelle Micaela S. Panganiban ; Mia P. Rey ; Carol Stephanie C. Tan-lim ; Mark Anthony U. Javelosa ; Ramon Pedro P. Paterno ; Ray U. Casile ; Leonila F. Dans ; Antonio L. Dans
Acta Medica Philippina 2025;59(1):66-72
BACKGROUND AND OBJECTIVE
Primary care providers are key players in providing quality care to patients and advancing Universal Health Care (UHC). However, effective and quality healthcare delivery may be affected by inadequate knowledge and failure to adhere to evidence-based guidelines among providers. The Philippine Primary Care Studies (PPCS) is a five-year program that pilot tested interventions aimed at strengthening the primary care system in the country. Evidence-based training modules for healthcare providers were administered in Sorsogon and Bataan from the years 2018 to 2021. Module topics were selected based on common health conditions encountered by providers in rural and remote settings. This program aimed to evaluate the effectiveness of training in increasing provider knowledge.
METHODSA series of training workshops were conducted among 184 remote- and 210 rural-based primary care providers [nurses, midwives, barangay or village health workers (BHWs)]. They covered four modules: essential intrapartum and newborn care (EINC), integrated management of childhood illness (IMCI), non-communicable diseases (NCD), and geriatrics. A decision support system (UpToDate) was provided as a supplementary resource for all participants. We administered pre-tests and post-tests consisting of multiple-choice questions on common health conditions. Data was analyzed using paired one-tailed t-test, with an alpha of 0.05.
RESULTSThe knowledge of nurses, midwives, and BHWs improved after the training workshops were conducted. The largest increase from pre-test to post-test scores were observed among the midwives, with a mean difference (MD) of 32.9% (95% CI 23.9 to 41.9) on the EINC module, MD of 25.0% (95% CI 16.6 to 33.4) in the geriatrics module, and MD of 13.5% (95% CI 6.9 to 20.1) in the NCDs module. The nurses had the greatest improvement in the IMCI module (MD 10.8%, 95% CI 2.5 to 19.1). The knowledge of BHWs improved in all participated modules, with greatest improvement in the NCD module (MD 9.0%, 95% CI 5.77 to 12.14).
CONCLUSIONSPrimary care workshops, even if conducted as single-sessions and on a short-term basis, are effective in improving short-term knowledge of providers. However, this may not translate to long-term knowledge and application in practice. Furthermore, comparisons across provider categories cannot be made as participant composition for each training workshop varied. Ultimately, this study shows enhancing provider knowledge and competence in primary care will therefore require regular and diverse learning interventions and access to clinical decision support tools.
Capacity Building ; Health Workforce ; Philippines ; Primary Health Care
6.Philippine clinical practice guidelines on screening, diagnosis, management and prevention of primary osteoporosis and fragility fractures among postmenopausal women and older men.
Julie LI-YU ; Angela SISON-AGUILAR ; Irewin TABU ; Joy BAUTISTA ; Eunice Victoria CO ; Seurinane Sean ESPAÑOLA ; Maria Eizelle FERNANDEZ ; Julie GABAT-TAN ; Tricia GUISON-BAUTISTA ; Lenore LUGUE-LIZARDO ; Eva Irene MAGLONZO ; Edmund MARTINEZ ; Daisy MEDINA ; Queenie NGALOB-SAMONTE ; Nathaniel ORILLAZA JR. ; Mary Ruth PADUA ; Joseph PATRICIO ; Jonathan RONQUILLO ; Ma. Carissa Abigail ROXAS-PANUDA ; Hannah URBANOZO-CORPUZ ; Angeli WYSON-WONG ; Irvin PARADA
Journal of the ASEAN Federation of Endocrine Societies 2025;40(2):18-26
BACKGROUND
This first clinical practice guideline (CPG) on osteoporosis prevention and management in the Philippines is the output of a shared undertaking by a multidisciplinary CPG development team spearheaded by the Osteoporosis Society of the Philippines Foundation, Inc. and joined by the Philippine Academy of Family Physicians; the Philippine College of Endocrinology, Diabetes, and Metabolism; the Philippine Orthopedic Association; the Philippine Obstetrics and Gynecological Society and the Philippine Rheumatology Association. This guideline seeks to augment and update the "Consensus statements on osteoporosis diagnosis, prevention and management in the Philippines," initially published in 2011, incorporating evidence-based practices developed in the last decade.
METHODOLOGYThe steering committee formulated and prioritized clinical questions based on meetings and stakeholder consultations. A PICO (population, intervention, comparator, outcome) format was used to develop clinical questions and guide the systematic search for evidence. The development of guidelines followed the ADAPTE process. Once completed, panel discussions were done using the Evidence to Decision Framework. After the panel discussions, the final recommendations were revised.
RESULTSThirty-four recommendations were formulated to address 27 clinical questions related to screening, prevention, diagnosis, pharmacologic and nonpharmacologic treatment, surgical management, follow-up, and continuity of care. With these recommendations, the developers aim to establish a standard of care in the prevention, diagnosis and management of osteoporosis and fragility fractures in both in-patient and out-patient cases that are appropriate to the Philippine context. Specifically, the CPG development group aims to use these recommendations to define the standard of care for osteoporosis as part of universal healthcare services once the program is implemented nationally. Relevant stakeholders may also use the recommendations to inform public and private payor policies for patients with fragility fractures, as well as by local government units or private companies looking to establish orthogeriatric centers with fracture liaison services.
CONCLUSIONThis guideline is helpful for physicians and other allied health personnel in screening, diagnosis, management and prevention of primary osteoporosis and fragility fractures among postmenopausal women and older men.
Human ; Philippines ; Guideline ; Osteoporosis
7.Blood transfusion in elective gynecological surgeries in the Philippines: A multicenter study
Maria Antonia E. Habana ; Ma. Carmen H. Quevedo ; Elisa O. Tiu ; Maria Corazon Zaida Noblejas Gamilla ; Madonna Victoria C. Domingo ; Maria Virginia S. Abalos ; Maria Lourdes K. Otayza ; Amelia A. Vega ; Lynnette R. Lu-lasala ; Czarina Juliana L. Alcaraz ; Efren J. Domingo ; Nancy Marie S. Gamo ; Delfin A. Tan
Philippine Journal of Obstetrics and Gynecology 2025;49(2):106-113
BACKGROUND
Intraoperative transfusion for gynecologic surgery, when appropriately used, can improve patient outcomes. However, when utilized incorrectly, blood transfusion can worsen patient outcomes and increase patient cost. This study aimed to evaluate the blood transfusion practices of tertiary hospitals in the Philippines.
METHODSThe study utilized a cross-sectional design wherein prospective data were gathered through multiple sources across seven tertiary-level hospitals. Women admitted to undergo gynecologic surgery were recruited based on a set of criteria. A chart review was conducted, and blood utilization indices were calculated. Outcomes were compared between public versus private facilities and transfused versus nontransfused patients.
RESULTSAmong 514 patients, 79.7% underwent cross-matching and 75.1% received transfusions. Adverse events were rare, with no transfusion-related deaths. The overall crossmatch-to-transfusion ratio (C/T ratio) was 2.8, exceeding the 2.5 optimal benchmark; all public hospitals recorded a C/T ratio >2.5, whereas private centers had more efficient usage. Six hospitals met acceptable benchmarks for transfusion probability and transfusion index. Open abdominal procedures, particularly hysterectomy, accounted for the most blood used. Transfused patients had longer operative times, greater blood loss, lower preoperative hemoglobin, and more frequently involved resident physicians in training. Public hospitals recorded higher cross-match and transfusion rates, greater resident physician participation, and broader use of general anesthesia.
CONCLUSIONResults of the study highlight the importance of monitoring blood transfusion parameters to optimize blood utilization. The observed differences between public and private institutions in the country highlight the urgent need for standardized and evidence-based practice to ensure efficient transfusion protocols nationwide.
Human ; Female ; Blood Transfusion
8.Digital health's impact on the patient-doctor relationship in a primary healthcare setting: A qualitative study.
Kai Ping SZE ; Yean Lyi LIM ; Qi Wei FONG ; Jacqueline Giovanna DE ROZA ; Poay Sian Sabrina LEE ; Eng Sing LEE ; Shu Yun TAN
Annals of the Academy of Medicine, Singapore 2025;54(2):129-131
9.Singapore Myeloma Study Group consensus guidelines for the management of patients with newly diagnosed multiple myeloma.
Sanjay DE MEL ; Allison Cy TSO ; Cinnie Y SOEKOJO ; Melissa G OOI ; Chi Ching LIM ; Constance TEO ; Yun Xin CHEN ; Melinda TAN ; Aditi MANJERI ; Zhao Yuan LEE ; Daryl TAN ; Liang King LEE ; Ling CAO ; Yeow Tee GOH ; Chandramouli NAGARAJAN ; Wee Joo CHNG
Annals of the Academy of Medicine, Singapore 2025;54(9):561-584


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