Objective:To assess the predictive value of acute liver failure (ALF) for sepsis-free survival (SFS) in burn patients and to identify associated risk factors.Methods:A retrospective cohort study was conducted on burn patients meeting inclusion criteria from the 2014 Kunshan aluminum dust explosion disaster (August 2, 2014 - April 13, 2015). Eligible patients were stratified into ALF and non-ALF groups based on the development of ALF. Demographic characteristics, total burn surface area, organ dysfunction, time to sepsis onset, and clinical outcomes were collected and compared between groups. Kaplan-Meier survival analysis and multivariate Cox regression were performed to assess the impact of ALF on SFS. A nomogram model was constructed for individualized risk prediction.Results:Among 185 enrolled patients (ALF group:21, non-ALF group:164), ALF incidence was 11.35%. The ALF group demonstrated higher mortality (85.71% vs. 34.15%, P<0.001) and SFS failure rates (100.00% vs. 61.59%, P<0.001) compared to non-ALF patients. Multivariate Cox analysis identified ALF as an independent sepsis predictor ( HR=1.68, 95% CI: 1.00-2.80, P<0.05). Time-dependent ROC analysis showed AUCs of 0.626, 0.714, 0.703, and 0.706 for SFS prediction at 2, 4, 8, and 12 weeks respectively. The nomogram model demonstrated that ALF combined with other parameters effectively predicted sepsis risk within 2-12 weeks post-injury. ALF development showed significant associations with concurrent organ dysfunction including acute kidney injury, acute heart failure, and acute respiratory distress syndrome (all P<0.001). A higher proportion of ALF patients received hemodialysis ( P<0.001) and pre-hospital central venous catheterization ( P=0.017). Conclusions:ALF independently predicts SFS failure and correlates strongly with poor prognosis in burn patients. Early ALF recognition and targeted interventions may facilitate sepsis risk stratification and precision prevention strategies.

Objective To explore the early intervention time and method for neonatal jaundice,to prevent excessive treatment and delay treatment.Methods From July 2014 to June 2014,240 full term neonates with high bilirubin value were divided into treatment group and observation group.The treatment group was given blue light treatment,the observation group was given general treatment such as intestinal probiotics,Yinzhihuang oral liquid.The treatment time,duration of jaundice of newborn babies,full refund yellow bilirubin value of time and follow-up at the 28th day were observed in two groups.Results In the two groups after treatment,without conversion of blood treatment in 1 case,1 case of bilirubin encephalopathy.In the control group,the treatment tine,the duration of jaundice,jaundice time were (7.84 ± 1.79) d,(10.40 ± 1.30) d,(13.85 ± 1.88) d,which in the treatment group were (4.55 ±1.63)d,(8.70 ± 1.50)d,(1 1.12 ± 1.65)d respectively,there were significant differences between the two groups (t =14.74,9.36,11.70,all P ＜ 0.01).In the control group,the bilirubin level at 28 d follow-up was (13.20 ± 2.47) μ mol/L,that of the treatment group was (12.06 ± 2.53)μ mol/L,there was no significant difference between the two groups(t =3.52,P ＞ 0.05).Conclusion The key of neonatal jaundice treatment is prevent the happening of the bilirubin encephalopathy,as long as jaundice intervention recommendation should be timely intervened.Blue light is the first selection of neonatal jaundice intervention method,treatment effect is exact;Full moon to the health of more than 3 days,total bilirubin blood although has reached the blue-ray standard treatment,on the premise of strict monitoring of bilirubin,can temporarily not blue light.

Objective To study the characteristics and regularities of somatotype of Bai ethnicitty children and adolescents in Hu ’ nan.Methods The somatotype growth of 1525 Bai children and adolescents ( male: 748, female:777) was evaluated by the Heath-Carter anthropometric method.Results The mesomorphy of male was bigger than that of female, and endomorphy of female was bigger than that of male .The primary somatotype in male was mesomorph and ectomorph , and it was central and ectomorph in female .The somatotypes developed from balanced mesomorph , ectomorphic mesomorph , mesomorph-ectomorph , mesomorphic ectomorph to mesomorph-ectomorph in male; however , in female from central, balanced ectomorph , central, endomorph-mesomorph to mesomorphic endomorph .Conclusion The somatotypes are very different between males and females of Bai ethnicity children and adolescents .The somatotype of males is slender with less fat and more muscular , however , they are plumper with more body fat and shorter stature in females .Bai ethnicity children and adolescents have less muscular , less fat and shorter stature than Mongolian and other populations .