1.The off-label prescribing drugs of inpatients with nonorganic sleep disorders
Su HONG ; Li KUANG ; Qi ZHANG ; Jinglan HE ; Liyang WAN ; Xiaosha YANG ; Shuo DAI ; Jian WEN ; Tong WU ; Sijing CHEN ; Daqin DING ; Mengyao WANG ; Yuhong LI ; Muni XIAO ; Lan HU
Chinese Journal of Psychiatry 2019;52(3):188-192
Objective To understand the current situation of the use of psychotropic drug off-label prescribing for nonorganic sleep disorder patients,and to provide evidence for the development of the expert consensus on off-label prescribing of psychoactive drugs in psychiatry.Methods Patients discharged in 2017 with nonorganic sleep disorders were enrolled in the study.The off-labelled prescribing of psychoactive drugs questionnaire was used to investigate the records retrospectively.The off-label prescribing situation was confirmed by the drug label in China.Results A total of 294 patients were enrolled.The total rate of off-labelled prescription was 70.1% (206/294),the rate of off-labelled indication was 68.4% (201/294),the rate of off-labelled population was 14.3%(41/294),and the rate of off-labelled dose was 5.4% (16/294).Conclusion Off-label usage of psychotropic drugs is common and to standarize off-label prescribing with close supervision should be considered.
2.The off-label prescribing drugs of inpatients with nonorganic sleep disorders
Su HONG ; Li KUANG ; Qi ZHANG ; Jinglan HE ; Liyang WAN ; Xiaosha YANG ; Shuo DAI ; Jian WEN ; Tong WU ; Sijing CHEN ; Daqin DING ; Mengyao WANG ; Yuhong LI ; Muni XIAO ; Lan HU
Chinese Journal of Psychiatry 2019;52(3):188-192
Objective To understand the current situation of the use of psychotropic drug off-label prescribing for nonorganic sleep disorder patients,and to provide evidence for the development of the expert consensus on off-label prescribing of psychoactive drugs in psychiatry.Methods Patients discharged in 2017 with nonorganic sleep disorders were enrolled in the study.The off-labelled prescribing of psychoactive drugs questionnaire was used to investigate the records retrospectively.The off-label prescribing situation was confirmed by the drug label in China.Results A total of 294 patients were enrolled.The total rate of off-labelled prescription was 70.1% (206/294),the rate of off-labelled indication was 68.4% (201/294),the rate of off-labelled population was 14.3%(41/294),and the rate of off-labelled dose was 5.4% (16/294).Conclusion Off-label usage of psychotropic drugs is common and to standarize off-label prescribing with close supervision should be considered.

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