1.Raman analysis of lipids in cells:Current applications and future prospects
Yixuan ZHOU ; Yuelin XU ; Xiaoli HOU ; Daozong XIA
Journal of Pharmaceutical Analysis 2025;15(4):665-678
Lipids play an important role in the regulation of cell life processes.Although there are various lipid detection methods,Raman spectroscopy,a non-invasive technique,provides the detailed chemical composition of lipid profiles without a complex sample preparation procedure and possesses greater potential in basic biology,clinical diagnosis and disease therapy.In this review,we summarized the characteristics and advantages of Raman-based techniques and their primary contribution to illustrating cellular lipid metabolism.
2.Visualization Analysis of Scientific Research Ability Training of Professional Degree Postgraduates of Traditional Chinese Medi-cine Based on CiteSpace
Xiaoxi ZHANG ; Fenfen LI ; Daozong XIA
Journal of Zhejiang Chinese Medical University 2025;49(8):1071-1077
[Objective]To investigate the research landscape,predominant themes and emerging trends in scientific research competency cultivation for traditional Chinese medicine(TCM)professional degree postgraduates in China over the past decade,in order to provide a reference for in-depth research on the cultivation of scitifin research capabilities of postgraduates in the professional degree in TCM.[Methods]A systematic literature review was conducted by using the China National Knowledge Infrastructure(CNKI)from January 1,2015 to December 31,2024,focusing on publications related to research capacity development for TCM professional degree programs.CiteSpace 6.4.R1 software was employed to perform bibliometric analyses of authorship patterns,institutional collaborations and keyword co-occurrence networks.[Results]A total of 103 eligible studies were included.The overall publication volume showed a significant increasing trend,with a rapid growth phase from 2020 to 2024,peaking at 18 articles in 2022,reflecting rising attention to this field.Author collaboration network analysis indicated that JIANG Youming and MO Jie topped the list with 3 publications each,while most other authors conducted research independently with limited cooperation.The institutional collaboration network had a density of 0.0096,indicating low inter-institutional cooperation,with Hu'nan University of Chinese Medicine leading in publications(5 articles).Keyword co-occurrence analysis revealed core research hotspots such as"training model""teaching reform""double-track integration".Keyword burst analysis showed prominent terms like"curriculum system""medical-education collaboration""clinical thinking""new medical discipline"from 2015 to 2024,with"new medical discipline"emerging as a recent hotspot reflecting interdisciplinary integration trends.[Conclusion]The number of articles on the scientific research ability cultivation for postgraduates of TCM professional degrees in China has generally increased,and the research scope has continuously expanded.However,there are differences in research levels among different regions.It is necessary to strengthen the cooperation between multi-disciplines and multi-regions,conduct broader and deeper research,and formulate scientific research ability training programs suitable for postgraduates of TCM professional degrees in China to further improve their scientific research ability.
3.Raman analysis of lipids in cells: Current applications and future prospects.
Yixuan ZHOU ; Yuelin XU ; Xiaoli HOU ; Daozong XIA
Journal of Pharmaceutical Analysis 2025;15(4):101136-101136
Lipids play an important role in the regulation of cell life processes. Although there are various lipid detection methods, Raman spectroscopy, a non-invasive technique, provides the detailed chemical composition of lipid profiles without a complex sample preparation procedure and possesses greater potential in basic biology, clinical diagnosis and disease therapy. In this review, we summarized the characteristics and advantages of Raman-based techniques and their primary contribution to illustrating cellular lipid metabolism.
4.Visualization Analysis of Scientific Research Ability Training of Professional Degree Postgraduates of Traditional Chinese Medi-cine Based on CiteSpace
Xiaoxi ZHANG ; Fenfen LI ; Daozong XIA
Journal of Zhejiang Chinese Medical University 2025;49(8):1071-1077
[Objective]To investigate the research landscape,predominant themes and emerging trends in scientific research competency cultivation for traditional Chinese medicine(TCM)professional degree postgraduates in China over the past decade,in order to provide a reference for in-depth research on the cultivation of scitifin research capabilities of postgraduates in the professional degree in TCM.[Methods]A systematic literature review was conducted by using the China National Knowledge Infrastructure(CNKI)from January 1,2015 to December 31,2024,focusing on publications related to research capacity development for TCM professional degree programs.CiteSpace 6.4.R1 software was employed to perform bibliometric analyses of authorship patterns,institutional collaborations and keyword co-occurrence networks.[Results]A total of 103 eligible studies were included.The overall publication volume showed a significant increasing trend,with a rapid growth phase from 2020 to 2024,peaking at 18 articles in 2022,reflecting rising attention to this field.Author collaboration network analysis indicated that JIANG Youming and MO Jie topped the list with 3 publications each,while most other authors conducted research independently with limited cooperation.The institutional collaboration network had a density of 0.0096,indicating low inter-institutional cooperation,with Hu'nan University of Chinese Medicine leading in publications(5 articles).Keyword co-occurrence analysis revealed core research hotspots such as"training model""teaching reform""double-track integration".Keyword burst analysis showed prominent terms like"curriculum system""medical-education collaboration""clinical thinking""new medical discipline"from 2015 to 2024,with"new medical discipline"emerging as a recent hotspot reflecting interdisciplinary integration trends.[Conclusion]The number of articles on the scientific research ability cultivation for postgraduates of TCM professional degrees in China has generally increased,and the research scope has continuously expanded.However,there are differences in research levels among different regions.It is necessary to strengthen the cooperation between multi-disciplines and multi-regions,conduct broader and deeper research,and formulate scientific research ability training programs suitable for postgraduates of TCM professional degrees in China to further improve their scientific research ability.

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