PURPOSE: To present the initial experience of percutaneous radiofrequency ablation (RFA) of inoperable primary lung cancer, and to assess the technical feasibility and potential complications. MATERIALS AND METHODS: Twenty patients with inoperable lung cancer underwent percutaneous RFA. Nineteen of 20 patients had stage III or IV non-small cell lung cancer, and the remaining one had stage I lung cancer with pulmonary dysfunction. The mean tumor size was 4.6+/-0.4 cm (range, 1.8-8.4 cm). RFA was performed with a single (n=18) or cluster (n=2) cool-tip RF electrode and a generator under CT guidance using local anesthesia and conscious sedation. Twenty tumors were treated in 28 sessions. Patients were assessed by contrast-enhanced CT in all cases at 1 week, 1 month, and 3 months. Eleven patients received chemotherapy (n=10) or radiotherapy (n=1) after RFA. RESULTS: RFA was technically successful and well tolerated in all patients. Complete necrosis was attained in 7 lesions (35%), near complete (90-99%) necrosis in 10 lesions (50%), and partial (50-89%) necrosis in 3 lesions (15%). During the mean follow up of 202 days (21 to 481 days), tumor size was decreased in 13 patients, unchanged in 3, and increased in 4. In the latter four, additional RFA was performed. One patient underwent surgery three months after RFA and the histopathologic findings showed a large cavity with thin fibrotic wall suggestive of complete necrosis. During or after the procedure, pneumothorax (n=10), moderate pain (n=4), blood tinged sputum (n=2), and pneumonia (n=2) were developed. Chest tube drainage was required in only 1 patient due to severe pneumothorax. Other patients were managed conservatively. Seven patients died at 61 to 398 days (mean, 230 days) after RFA. The remaining 13 patients were alive 21 to 481 days (mean, 187 days) after RFA. CONCLUSION: RFA appears to be a technically feasible and relatively safe procedure for the cytoreductive treatment of inoperable, non-small cell lung cancer and warrants further investigation as a complementary treatment to chemotherapy or radiation therapy.
Anesthesia, Local ; Carcinoma, Non-Small-Cell Lung ; Catheter Ablation* ; Chest Tubes ; Conscious Sedation ; Drainage ; Drug Therapy ; Electrodes ; Follow-Up Studies ; Humans ; Lung Neoplasms* ; Lung* ; Necrosis ; Pneumonia ; Pneumothorax ; Radiotherapy ; Sputum ; Tolnaftate ; Tomography, X-Ray Computed

No abstract available.
Diagnosis* ; Ultrasonography* ; Varicocele*

PURPOSE: Our aim is to identify the false negative rate of doppler ultrasonography and to compare color doppler ultrasonography with pathologic findings during testis torsion in animal model. MATERIALS AND METHODS: Seventeen male house rabbits weighted 1.9-2.6kg were examined with doppler ultrasonography as control group and 1 rabbit was orchiectomized as pathologic control group. In 16 rabbits, right spermatic cord was torqued 720o count-clockwise and placed back into the scrotum, and 1, 3, 6, 9, 12, 18, 24, 48 hours after torsion, doppler ultrasonographic and pathologic findings were examined at twisted testicles. RESULTS: In 1 hour and 3 hours group, false negative rate of doppler ultrasonography were 100% and 6 hours after torsion false nagative rate was 63%. Nine hours after torsion false negative rate was 50%, 12 hours after torsion false negative rate was 25%. But after 18 hours group, all had decreased or disappeared blood flow. Before 9 hours after torsion, there was no pathologic changes in seminiferous tubules. In seminiferous tubules, number of spermatid decreased in 12 hours group and spermatid was absent and spermatocyte were markedly degenerated in 18 hours group. In 48 hours group, spermatid and spermatocyte were absent, number of Sertoli cell decreased markedly and diffuse infarction were seen. CONCLUSIONS: As time goes by, false negative rate of doppler ultrasonography was decreased. So if blood flow have been normal when doppler ultrasonography was done before 12 hours after torsion, doppler ultrasonography should be re-examined in suspected testis before 12 hours after torsion because of spermatocytes are degenerated after 12 hours.
Animals* ; Humans ; Infarction ; Male ; Models, Animal* ; Rabbits ; Scrotum ; Seminiferous Tubules ; Spermatic Cord ; Spermatids ; Spermatocytes ; Testis* ; Ultrasonography, Doppler* ; Ultrasonography, Doppler, Color

Statistical observation was made on 809 in-patient in the Department of Urology, College of Medicine, Hanyang University from May 3, 1972 to December 31, 1976.
Humans ; Inpatients ; Urology

A case of retroperitoneal teratoma in a 37-year old woman is presented. For approximately 20 years, she suffered from a slowly growing palpable mass and discomfort and pain in the LUQ. Upper GI series revealed compression and displacement of the greater curvature of the body of the stomach, and the outline of a large LUQ. mass overlapping the left kidney. IVP demonstrated compression of the left renal pelvis and calyceal system by this large mass, and considerable amorphous calcification in the upper pole of the mass. Pre-operatively, the mass was suspected to be a dermoidcyst or teratoma or pancreatic pseudocyst. At the operation, it proved to be a large retroperitoneal tumor mass of infant-head size, and it extended to the pancrestic hilum, including the upper pole of the left kidney, with adhesion to the left mesocolon. This huge tumor mass and involved left kidney were widely removed.
Adult ; Female ; Humans ; Kidney Pelvis ; Kidney* ; Mesocolon ; Pancreatic Pseudocyst ; Stomach ; Teratoma*

Two patient underwent transpubic repair of posterior urethral strictures. Wedge resection of pubic bone was provided excellent exposure for urethroplasty and no orthopedic disability. The result was satisfactory in the patient without affect continence or potency.
Humans ; Orthopedics ; Pubic Bone ; Urethral Stricture*

The congenital unilateral agenesis is defined as the complete absence of one kidney due to the fact that the ureteral bud fails to develop or, if it does develop, does not reach the metanephros. It is usually found by accident on urography. We have experienced 2 cases of congenital unilateral renal agenesis accompanied by tuberculous epididymitis, proved by radiologically and surgically and report with brief review of the literatures.
Epididymitis ; Kidney ; Male ; Tuberculosis* ; Ureter ; Urography

A case of foreign body (a piece of wood) in the bladder by penetrating perineal injury was presented in a 13 years old Korean boy and reported with review of literature.
Adolescent ; Foreign Bodies* ; Humans ; Male ; Urinary Bladder*

A l3-year-old boy was admitted to our hospital with severe hypertension, visual blurring, excessive sweating, polyuria and polydipsia. On admission, the blood pressure was persistently elevated at 230/180 mmHg. and an ophthalmologist was consulted, the funduscopic examination showed bilateral grade IV retinopathy. Cardiomegaly with dyspneic on exertion and persistent tachycardia were present. In urine examinations, proteinuria was sustained and glycosuria was traced. B. U. N. was 9.4 mg/dl. Urinary catecholamine was 12480 mic.g./day ; urinary V. M. A. was 20.2 mg./day. Regitine test was positive but histamine test was not performed. Presacral air insufflation with nephrotomography showed egg sized soft tissue mass locating at just above the upper pole of left kidney. He was operated with transabdominal approach. There were bilateral pheochromocytomas on suprarenal areas. Two weeks after operation, he was discharged with good general condition and we report this case with review of literatures.
Blood Pressure ; Cardiomegaly ; Glycosuria ; Histamine ; Humans ; Hypertension ; Insufflation ; Kidney ; Male ; Ovum ; Phentolamine ; Pheochromocytoma* ; Polydipsia ; Polyuria ; Proteinuria ; Sweat ; Sweating ; Tachycardia

A clinical observation was made on cryptorchism of the in patients in the Department of Urology, Severance Hospital during the period January, 1960 through December, 1969. 1) During the period, 823 male patients hospitalized, there were 53 cases of cryptorchism, giving a rate of 6.5% respectively. 2) Of the cases of cryptorchism, 15 cases (28. 4%) were observed at 5 year old or below and to one's misery, 26 cases (50%) were seen at over 11 year old. 3) Lateralization shows 18 cases or 34% in the bilateral and 35 cases 66% in the unilateral (19 cases in right side and 16 cases in left side). 4) Position of undescended testis is most popular in the inguinal type (73%) and intraabdominal type is 11 testes (15%). 5) Of presenting symptoms, pain sensation on the inguinal region was observed in 10 cases(19%).
Child ; Child, Preschool ; Cryptorchidism* ; Humans ; Male ; Sensation ; Testis ; Urology