Objective To explore mental well-being and the relationship with resilience amongst younger and older migrant workers from service industries in Shenzhen. Methods A cross-sectional study was conducted in Shenzhen city,a total of 1 979 rural-to-urban migrant workers were recruited from the community by the method of respondent-driven sampling. Mental wellbeing and resilience was measured using the Center for Epidemiologic Studies Depression Scale(CES-D), Generalized Anxiety Disorder-7 (GAD-7), Connor-Davidson Resilience Scale(CD-RISC) and Perceived Social Support Scale(PSSS). The scores of depression, anxiety and resilience between younger and older migrant workers were compared,and multiple linear regression analysis was used to identify independent factors associated with depression and anxiety in these two groups respectively. Results Younger migrant group showed higher scores of positive emotion subscale of CES-D((5.04±2.41):(4.53±2.33);t=4.567,P=0.000),as well as total scores((82.94± 16.82):(79.87 ± 17.99);t=3.720,P=0.000), tenacity((42.57 ± 9.26):(41.17 ± 9.72);t=3.119,P=0.002), strength((27.93±5.86):(26.60±6.34);t=4.592,P=0.000)and optimism((12.44±2.91):(12.10±3.14);t=2.364,P=0.018)of CD-RISC compared to older group. Linear regression analysis showed factors that were independently negatively associated with depression and anxiety in younger migrants included tenacity and strength,and strength contributed most to depression(standard coefficient β=-0.376, R2=0.123). Whereas strength was negatively associated with depression(standard coefficient β=-0.298, R2=0.069)and anxiety (standard coefficientβ=-0.089, R2=0.022)in older migrants. Conclusions The general mental wellbeing between younger and older migrants may be equal. The resilience is better in younger migrants and predicts depression and anxiety. Efforts to enhance the resilience may be useful to promote mental wellbeing among younger migrant workers.

Objective To explore mental well-being and the relationship with resilience amongst younger and older migrant workers from service industries in Shenzhen. Methods A cross-sectional study was conducted in Shenzhen city,a total of 1 979 rural-to-urban migrant workers were recruited from the community by the method of respondent-driven sampling. Mental wellbeing and resilience was measured using the Center for Epidemiologic Studies Depression Scale(CES-D), Generalized Anxiety Disorder-7 (GAD-7), Connor-Davidson Resilience Scale(CD-RISC) and Perceived Social Support Scale(PSSS). The scores of depression, anxiety and resilience between younger and older migrant workers were compared,and multiple linear regression analysis was used to identify independent factors associated with depression and anxiety in these two groups respectively. Results Younger migrant group showed higher scores of positive emotion subscale of CES-D((5.04±2.41):(4.53±2.33);t=4.567,P=0.000),as well as total scores((82.94± 16.82):(79.87 ± 17.99);t=3.720,P=0.000), tenacity((42.57 ± 9.26):(41.17 ± 9.72);t=3.119,P=0.002), strength((27.93±5.86):(26.60±6.34);t=4.592,P=0.000)and optimism((12.44±2.91):(12.10±3.14);t=2.364,P=0.018)of CD-RISC compared to older group. Linear regression analysis showed factors that were independently negatively associated with depression and anxiety in younger migrants included tenacity and strength,and strength contributed most to depression(standard coefficient β=-0.376, R2=0.123). Whereas strength was negatively associated with depression(standard coefficient β=-0.298, R2=0.069)and anxiety (standard coefficientβ=-0.089, R2=0.022)in older migrants. Conclusions The general mental wellbeing between younger and older migrants may be equal. The resilience is better in younger migrants and predicts depression and anxiety. Efforts to enhance the resilience may be useful to promote mental wellbeing among younger migrant workers.

OBJECTIVETo conduct the biotransformation of ursolic acid by alternaria longipes AS3. 2875, and optimize the culture medium and biotransformation conditions.

METHODWith the consumption rate of ursolic acid and the generation rate of 28-O-beta-D-glucopyranose ursolic acid as indicators, the impact of different biotransformation conditions such as pH, phosphate, different kinds of metal ions, spore concentration, substrate quantity, temperature, shaking speed and cultivation time on the transformation of ursolic acid in alternaria longipes culture solution were detected to obtain the optimal biotransformation conditions of ursolic acid by alternaria longipes.

RESULTThe optimized biotransformation conditions were as follows: initial pH value was 5.0, MgSO4 was 0.25 g x L(-1) K2HPO4 was 1.0 g x L(-1), FeSO4 was 0.083 g x L(-1), spore concentration was 4%, substrate quantity was 0.3 g x L(-1), shaking speed was 140 r x min(-1), cultivation temperature was at 28 degrees C and cultivating time was 3 days.

CONCLUSIONThe generation rate of 28-O-beta-D-glucopyranose ursolic acid by alternaria longipes stabilizes at around 5%.

Alternaria ; chemistry ; metabolism ; Biotransformation ; Culture Media ; metabolism ; Culture Techniques ; methods ; Hydrogen-Ion Concentration ; Temperature ; Triterpenes ; analysis ; metabolism

Aim To investigate the water-soluble phenolic glycosides from the whole plant of Bulbophyllum odoratissimum. Methods Column chromatography techniques were used to isolate the chemical constituents, physico-chemical constants and spectroscopic analysis were employed for structural elucidation. Results Bulbophyllinoside (1), a new phenolic glycoside and three known compounds were isolated from the whole plant of Bulbophyllum odoratissimum Lindl. Their structures were determined as 3-hydroxyphenethyl alcohol 4-O-(6'-O-β-apiofuranosyl)-β-D-glucopyranoside (1), 3-methoxyphenethyl alcohol 4-O-β-D-glucopynanoside (2), 3,5-dimethoxyphenethyl alcohol 4-O-β-D-glucopynanoside (3) and syringin (4). Conclusion Bulbophyllinoside (1) is a new compound.