1.Long-Term Risk of Cardiovascular Disease Among Type 2 Diabetes Patients According to Average and Visit-to-Visit Variations of HbA1c Levels During the First 3 Years of Diabetes Diagnosis
Hyunah KIM ; Da Young JUNG ; Seung-Hwan LEE ; Jae-Hyoung CHO ; Hyeon Woo YIM ; Hun-Sung KIM
Journal of Korean Medical Science 2023;38(4):e24-
Background:
It remains unclear whether a combination of glycemic variability and glycated hemoglobin (HbA1c) status leads to a higher incidence of cardiovascular disease (CVD).Therefore, to investigate CVD risk according to the glucose control status during early diabetes, we examined visit-to-visit HbA1c variability among patients with type 2 diabetes (T2DM).
Methods:
In this 9-year retrospective study, we measured HbA1c levels at each visit and tracked the change in HbA1c levels for 3 years after the first presentation (observation window) in newly diagnosed T2DM patients. We later assessed the occurrence of CVD in the last 3 years (target outcome window) of the study period after allowing a 3-year buffering window. The HbA1c variability score (HVS; divided into quartiles, HVS_Q1–4) was used to determine visit-to-visit HbA1c variability.
Results:
Among 4,817 enrolled T2DM patients, the mean HbA1c level was < 7% for the first 3 years. The group with the lowest HVS had the lowest rate of CVD (9.4%; 104/1,109 patients).The highest incidence of CVD of 26.7% (8/30 patients) was found in HVS [≥ 9.0%]_Q3, which was significantly higher than that in HVS [6.0–6.9%]_Q1 (P = 0.006), HVS [6.0–6.9%]_Q2 (P = 0.013), HVS [6.0–6.9%]_Q3 (P = 0.018), and HVS [7.0–7.9%]_Q3 (P = 0.040).
Conclusion
To our knowledge, this is the first long-term study to analyze the importance of both HbA1c change and visit-to-visit HbA1c variability during outpatient visits within the first 3 years. Lowering glucose levels during early diabetes may be more critical than reducing visit-to-visit HbA1c variability.
2.Impact of Coronavirus Disease 2019 on Gastric Cancer Diagnosis and Stage:A Single-Institute Study in South Korea
Moonki HONG ; Mingee CHOI ; JiHyun LEE ; Kyoo Hyun KIM ; Hyunwook KIM ; Choong-Kun LEE ; Hyo Song KIM ; Sun Young RHA ; Gyu Young PIH ; Yoon Jin CHOI ; Da Hyun JUNG ; Jun Chul PARK ; Sung Kwan SHIN ; Sang Kil LEE ; Yong Chan LEE ; Minah CHO ; Yoo Min KIM ; Hyoung-Il KIM ; Jae-Ho CHEONG ; Woo Jin HYUNG ; Jaeyong SHIN ; Minkyu JUNG
Journal of Gastric Cancer 2023;23(4):574-583
Purpose:
Gastric cancer (GC) is among the most prevalent and fatal cancers worldwide.National cancer screening programs in countries with high incidences of this disease provide medical aid beneficiaries with free-of-charge screening involving upper endoscopy to detect early-stage GC. However, the coronavirus disease 2019 (COVID-19) pandemic has caused major disruptions to routine healthcare access. Thus, this study aimed to assess the impact of COVID-19 on the diagnosis, overall incidence, and stage distribution of GC.
Materials and Methods:
We identified patients in our hospital cancer registry who were diagnosed with GC between January 2018 and December 2021 and compared the cancer stage at diagnosis before and during the COVID-19 pandemic. Subgroup analyses were conducted according to age and sex. The years 2018 and 2019 were defined as the “before COVID” period, and the years 2020 and 2021 as the “during COVID” period.
Results:
Overall, 10,875 patients were evaluated; 6,535 and 4,340 patients were diagnosed before and during the COVID-19 period, respectively. The number of diagnoses was lower during the COVID-19 pandemic (189 patients/month vs. 264 patients/month) than before it.Notably, the proportion of patients with stages 3 or 4 GC in 2021 was higher among men and patients aged ≥40 years.
Conclusions
During the COVID-19 pandemic, the overall number of GC diagnoses decreased significantly in a single institute. Moreover, GCs were in more advanced stages at the time of diagnosis. Further studies are required to elucidate the relationship between the COVID-19 pandemic and the delay in the detection of GC worldwide.
3.Uterine Artery Embolization as an Effective Management and Diagnostic Tool for Puerperal Uterine Inversion with Severe Postpartum Bleeding: A Case Report
Seong Ju KIM ; Youngjong CHO ; Sung-Joon PARK ; Sangjoon LEE ; Hyoung Nam LEE ; Da Hye JU
Journal of the Korean Radiological Society 2022;83(3):699-704
Acute puerperal uterine inversion is a rare postpartum obstetric complication; however, without rapid diagnosis and appropriate management, it is life-threatening. Substantial bleeding hinders the verification of a partially inverted uterus, possibly delaying the treatment. Herein, we present the report of a 32-year-old female presenting with massive postpartum bleeding managed by uterine artery embolization. The peculiar course of the uterine artery bowing inferiorly along the inverted fundus during embolization could uncover the uterine inversion, which was not diagnosed by physical examination and CT. In conclusion, uterine artery embolization is not only an effective therapeutic strategy for postpartum hemorrhage but also a valuable tool for diagnosing uterine inversion.
4.The Influence of Dental Hygienists’ Self-Leadership on Organizational Commitment and Quality of Medical Services
Da-Eun LEE ; Do-Seon LIM ; Min-Ji PARK ; Se-Jeong PARK ; Chi-Yoon SUNG ; Sang-In LEE ; Ha-Rim LEE ; Hyoung-Joo KIM ; Hee-Jung LIM
Journal of Dental Hygiene Science 2022;22(4):222-232
Background:
Self-leadership, an action strategy that can maximize individual capabilities, can affect the organizational commitment of dental hygienists and ultimately improve the quality of medical services. This study aims to demonstrate the need for self-leadership and organizational commitment for dental hygienists and develop measures to improve the quality of medical services.
Methods:
An online survey of dental hygienists working at dental hospitals and clinics in Seoul and Gyeonggi province, Republic of Korea was conducted from March 28 to May 1, 2022. A total of 341 questionnaires were returned and analyzed. The measurement tools were modified and supplemented based on the theories and models developed by Manz for self-leadership, Mowday for organizational commitment, and Cronin and Taylor for medical services. Descriptive statistics, independent t-tests, ANOVA, simple regression, and multiple regression analyses were performed using SPSS 25.0.
Results:
In leadership education, self-leadership is based on participation experience, the number of participants, and when and where it is received. Organizational commitment comes from participation experience, and the quality of medical services has been found to affect participation experience and location. Self-leadership had an effect on the quality of medical services (β=0.497, t=10.551, p<0.001; β =0.599, t=13.783, p<0.001; β=0.353, t=7.601, p<0.001) and organizational commitment was found to have a mediating effect.
Conclusion
Dental hygienists’ self-leadership has a positive effect on the quality of medical services through the formation of appropriate interrelationships within the organization. Therefore, self-leadership programs should be developed, participated in, and promoted to improve the self-leadership of dental hygienists. Moreover, hospitals should improve their environment to provide and improve self-leadership education.
5.Long-Term Changes in HbA1c According to Blood Glucose Control Status During the First 3 Months After Visiting a Tertiary University Hospital
Hyunah KIM ; Da Young JUNG ; Seung-Hwan LEE ; Jae-Hyoung CHO ; Hyeon Woo YIM ; Hun-Sung KIM
Journal of Korean Medical Science 2022;37(38):e281-
Background:
We evaluated patients visiting a tertiary university hospital due to a diagnosis of diabetes with a goal of achieving blood glucose control and evaluated blood glucose persistence over 7 years according to the change in blood glucose evident at 3 months after the first visit.
Methods:
Patients treated from 2009 to 2013 were categorized into four groups according to the change in HbA1c levels during the first 3 months of follow-up (Best_group, ≥ 1.6% decrease; Better_group, 0.5–1.5% decrease; Neutral_group, maintained at −0.4% to +0.4%; Worse_group, ≥ 0.5% increase). Each patient’s blood glucose control status was then monitored for 7 years. The incidence of stroke and acute coronary syndrome during this period was confirmed.
Results:
Overall, 9,776 patients were included. HbA1c values were lower in the Best_group than in the other groups at all time points (all P < 0.001). The rate of reaching targets of < 6.5% or < 7.0% HbA1c decreased over time; the rate at which the estimated glomerular filtration rate decreased to < 30 or < 60 mL/min/1.73m 2 increased over time (all trends, P < 0.01).
Conclusion
Blood glucose control status in the first 3 months after initiating hospital care enabled estimation of the patient’s glycemic control status for the next 7 years. In cases with poor initial blood glucose control, a new or more active method of blood glucose control should be sought.
6.The role of neutrophil-to-lymphocyte ratio for the prediction of intensive care unit admission among community-acquired pneumonia patients, hospitalized through the emergency department
Da Hyoung LEE ; Seon Yeong PARK ; Sang Hyun PARK ; Soo Hyun KIM ; Jongho ZHU ; Seung Pil CHOI ; Jae Hun OH
Journal of the Korean Society of Emergency Medicine 2022;33(4):338-345
Objective:
Multiple criteria have been proposed to assess the severity of community-acquired pneumonia (CAP) and predict intensive care unit (ICU) admissions. The neutrophil-to-lymphocyte ratio (NLR) is an inflammatory marker actively researched as a prognostic indicator in various infectious diseases. This study assessed the value of the NLR in predicting ICU admissions among CAP hospitalizations through the emergency department (ED).
Methods:
A retrospective observational study of hospitalized patients with CAP via ED was performed from March 2017 to December 2018 using electronic medical records from a single center. By analyzing the clinical data at the initial presentation to the emergency room, the predictability of NLR on the admissions to the ICU was compared with other preexisting clinical scores, such as PSI (Pneumonia Severity Index), CURB-65 (Confusion, Uremia, Respiratory rate, Blood pressure, Age ≥ 65 years), and APACHE II (Acute Physiology and Chronic Health Evaluation II) scores.
Results:
Of 599 CAP hospitalizations, 80 (13.4%) required ICU admissions. In multivariate logistic analysis, mean arterial pressure and NLR have significance in predicting ICU admission. The area of under curve (AUC) of preexisting clinical scores to predict ICU admission had a PSI of 0.70, CURB-65 of 0.58, and APACHE II score of 0.66. The AUC of the NLR model was 0.75, the highest among the preexisting scoring systems. Setting the NLR model as a reference value, the PSI and APACHE II scores showed no statistically significant difference in contrast to CURB-65, which showed less powerful predictability.
Conclusion
NLR is a simple, inexpensive, and rapidly available measurement in the ED, which can be used as a useful tool for predicting ICU admissions among patients with CAP over other preexisting clinical scores.
7.Regional Gaps in Health Status Estimated by Amenable Mortality Rate in Korea
Sei-Jong BAEK ; Heenyun KIM ; Da-Ho LEE ; Hyoung-Sun JEONG
Health Policy and Management 2021;31(1):100-113
Background:
This study aims to figure out the gaps in health status by estimating amenable mortality rate by region, reflecting the characteristics of Korea, and estimating the years of life lost (YLL) per capita by disease.
Methods:
People who died from amenable diseases between 2008 and 2018 were extracted from the cause of death statistics provided by Statistics Korea. The age-standardized amenable mortality rates were estimated to compare the health status of 229 regions. YLL per capita was calculated to compute the burden of diseases caused by treatable deaths by region. The YLL per capita by region was calculated to identify the burden of disease caused by amenable deaths.
Results:
First, while the annual amenable mortality rate in Korea is on a steady decline, but there is still a considerable gap between urban and rural areas when comparing the mortality rates of 229 areas. Second, YLL per capita due to the amenable deaths is approximately 14 person-years during the analysis period (2008–2018).
Conclusion
Although the health status of Koreans has continuously improved, there is still a gap in health status region by region in terms of amenable mortality rates. Amenable death accounts for a loss of life equivalent to 14 person-years per year. Since the amenable mortality rate is an indicator that can measure the performance of the health care system, efforts at each local area are required to lower it.
8.Regional Gaps in Health Status Estimated by Amenable Mortality Rate in Korea
Sei-Jong BAEK ; Heenyun KIM ; Da-Ho LEE ; Hyoung-Sun JEONG
Health Policy and Management 2021;31(1):100-113
Background:
This study aims to figure out the gaps in health status by estimating amenable mortality rate by region, reflecting the characteristics of Korea, and estimating the years of life lost (YLL) per capita by disease.
Methods:
People who died from amenable diseases between 2008 and 2018 were extracted from the cause of death statistics provided by Statistics Korea. The age-standardized amenable mortality rates were estimated to compare the health status of 229 regions. YLL per capita was calculated to compute the burden of diseases caused by treatable deaths by region. The YLL per capita by region was calculated to identify the burden of disease caused by amenable deaths.
Results:
First, while the annual amenable mortality rate in Korea is on a steady decline, but there is still a considerable gap between urban and rural areas when comparing the mortality rates of 229 areas. Second, YLL per capita due to the amenable deaths is approximately 14 person-years during the analysis period (2008–2018).
Conclusion
Although the health status of Koreans has continuously improved, there is still a gap in health status region by region in terms of amenable mortality rates. Amenable death accounts for a loss of life equivalent to 14 person-years per year. Since the amenable mortality rate is an indicator that can measure the performance of the health care system, efforts at each local area are required to lower it.
9.Analysis of Factors Affecting the Smoking Rates Gap between Regions and Evaluation of Relative Efficiency of Smoking Cessation Projects
Heenyun KIM ; Da Ho LEE ; Ji Yun JEONG ; Yeo Jeong GU ; Hyoung Sun JEONG
Health Policy and Management 2020;30(2):199-210
Background:
Based on the importance of ceasing smoking programs to control the regional disparity of smoking behavior in Korea, this study aims to reveal the variation of smoke rate and determinants of it for 229 provinces. An evaluation of the relative efficiency of the cease smoking program under the consideration of regional characteristics was followed.
Methods:
The main sources of data are the Korean Statistical Information Service and a national survey on the expenditure of public health centers. Multivariate regression is performed to figure the determinants of regional variation of smoking rate. Based on the result of the regression model, clustering analysis was conducted to group 229 regions by their characteristics. Three clusters were generated. Using data envelopment analysis (DEA), relative efficiency scores are calculated. Results from the pooled model which put 229 provinces in one model to score relative efficiency were compared with the cluster-separated model of each cluster.
Results:
First, the maximum variation of the smoking rate was 16.9%p. Second, sex ration, the proportion of the elder, and high risk drinking alcohol behavior have a significant role in the regional variation of smoking. Third, the population and proportion of the elder are the main variables for clustering. Fourth, dissimilarity on the results of relative efficiency was found between the pooled model and cluster-separated model, especially for cluster 2.
Conclusion
This study figured regional variation of smoking rate and its determinants on the regional level. Unconformity of the DEA results between different models implies the issues on regional features when the regional evaluation performed especially on the programs of public health centers.
10.Effects of Vojta Therapy on the Forced Vital Capacity and Forced Expiratory Volume at One Second in Young Male Smokers: A Single-Subject Design
Jin Seon KIM ; Da Young KIM ; Hee Sun KIM ; Si Won PARK ; Yun Jeong LEE ; Hyoung Won LIM
Journal of Korean Physical Therapy 2019;31(5):261-265
PURPOSE: This study examined the effects of Vojta therapy on the respiratory function in young male smokers.METHODS: Three subjects were tested using the ABA design for Single-subject Experimental Research Design. This study was conducted with the baseline, intervention, and follow-up phase. Intervention was conducted three to four times a week for 20 minutes per times and a total of 25 sessions. The respiratory function was measured using a Spirometer.RESULTS: The results of Forced Vital Capacity and Forced Expiratory Volume at one second for all subjects showed improvements in the intervention phase over the baseline phase. In the follow-up phase, the improved ability was still maintained or slightly reduced.CONCLUSION: Vojta therapy used on young male smokers was effective in both FVC and FEV1. In other words, the Vojta therapy worked effectively in improving the respiratory function. In future studies, it is necessary to have a control group and increase the number of trials in order to generalize the effect of Vojta therapy.
Follow-Up Studies
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Forced Expiratory Volume
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Humans
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Male
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Research Design
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Smoking
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Vital Capacity

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