Objective With the continuous development of human-machine interaction,human movement monitoring technology and health management level,ionic conductive hydrogels with excellent elasticity and biocompatibility have been increasingly used in the fields of wearable devices and aerospace medicine.In order to solve the problems of poor mechanical properties and unstable sensing signals of traditional ion-conductive hydrogels,it is of great significance to develop hydrogel materials with excellent performance.Methods The polyacrylamide/gelatin(PAM/Gelatin)dual-network ionic conductive hydrogels were prepared by a two-step method,and a systematic study of the chemical structure,mechanical properties and strain sensing response characteristics was carried out.Results The prepared hydrogels have high transparency and good tensile properties,and exhibit high sensitivity(GF=9.40),fast response and excellent response stability in the 0-800％strain range,which can realize the real-time monitoring of complex human motion and physiological signals.Conclusion The prepared hydrogel possesses excellent mechanical and sensing properties,and has potential applications in the wearable medical monitoring,especially in human physiological signal detection in aerospace medicine.