Objective:To evaluate the effects of fortified whey protein enteral nutrition preparations on the nutritional status and disease benefit perception of patients with advanced non-small cell lung cancer (NSCLC) during chemotherapy.Methods:A total of 96 patients with advanced non-small cell lung cancer admitted to the Chang′an Hospital from June 2020 to June 2023 were included and divided into two groups according to the random number table method. The control group ( n=48) received standard chemotherapy and conventional nutritional support, while the observation group ( n=48) was treated with whey protein and enteral nutrition preparations in addition to the control group. During the treatment period, the nutritional sign indicators of the patients [body mass index (BMI), triceps skinfold thickness (TSF), Patient-Generated Subjective Global Assessment (PG-SGA) score], serum indicators [albumin (ALB), prealbumin (PAB), hemoglobin (Hb)], and immune function (CD3 + , CD4 + , CD8 + , CD4 + /CD8 + ) patient quality of life scores [Karnofsky Performance Status (KPS), Zubrod Performance Status (ZPS), Quality of Life Score (QOL)], Specific Disease Benefit Scale (BFS) score and chemotherapy response were monitored. Results:After chemotherapy, the levels of ALB, PAB and Hb in the observation group were significantly higher than those in the control group (all P<0.05), BMI and TSF were significantly higher than those in the control group, PG-SGA score was significantly lower than that in the control group ( P<0.05), and CD3 + , CD4 + and CD4 + /CD8 + were significantly higher than those in the control group (all P<0.05). CD8 + was lower than that of the control group ( P<0.05); The KPS and QOL of patients in the observation group were significantly higher than those in the control group, and the ZPS was significantly lower than that in the control group. The differences were statistically significant (all P<0.05). The scores of acceptance, healthy behavior and personal growth dimensions of the BFS score in the observation group were significantly higher than those in the control group (all P<0.05). During the intervention period, the incidence of gastrointestinal reactions and thrombocytopenia in the observation group was significantly lower than that in the control group (all P<0.05). Conclusions:The fortified whey protein enteral nutrition preparations have a significant improvement effect on the nutritional status and disease benefit perception of patients with advanced NSCLC during chemotherapy, and may help improve the overall condition and chemotherapy tolerance of patients.

Objective:To evaluate the effects of fortified whey protein enteral nutrition preparations on the nutritional status and disease benefit perception of patients with advanced non-small cell lung cancer (NSCLC) during chemotherapy.Methods:A total of 96 patients with advanced non-small cell lung cancer admitted to the Chang′an Hospital from June 2020 to June 2023 were included and divided into two groups according to the random number table method. The control group ( n=48) received standard chemotherapy and conventional nutritional support, while the observation group ( n=48) was treated with whey protein and enteral nutrition preparations in addition to the control group. During the treatment period, the nutritional sign indicators of the patients [body mass index (BMI), triceps skinfold thickness (TSF), Patient-Generated Subjective Global Assessment (PG-SGA) score], serum indicators [albumin (ALB), prealbumin (PAB), hemoglobin (Hb)], and immune function (CD3 + , CD4 + , CD8 + , CD4 + /CD8 + ) patient quality of life scores [Karnofsky Performance Status (KPS), Zubrod Performance Status (ZPS), Quality of Life Score (QOL)], Specific Disease Benefit Scale (BFS) score and chemotherapy response were monitored. Results:After chemotherapy, the levels of ALB, PAB and Hb in the observation group were significantly higher than those in the control group (all P<0.05), BMI and TSF were significantly higher than those in the control group, PG-SGA score was significantly lower than that in the control group ( P<0.05), and CD3 + , CD4 + and CD4 + /CD8 + were significantly higher than those in the control group (all P<0.05). CD8 + was lower than that of the control group ( P<0.05); The KPS and QOL of patients in the observation group were significantly higher than those in the control group, and the ZPS was significantly lower than that in the control group. The differences were statistically significant (all P<0.05). The scores of acceptance, healthy behavior and personal growth dimensions of the BFS score in the observation group were significantly higher than those in the control group (all P<0.05). During the intervention period, the incidence of gastrointestinal reactions and thrombocytopenia in the observation group was significantly lower than that in the control group (all P<0.05). Conclusions:The fortified whey protein enteral nutrition preparations have a significant improvement effect on the nutritional status and disease benefit perception of patients with advanced NSCLC during chemotherapy, and may help improve the overall condition and chemotherapy tolerance of patients.

Objective:To investigate the current status and related factors of psychological distress in tele-phone operators.Methods:Totally 575 telephone operators from sample of a convenient survey in a certain telecom-munication company of Shandong Province were selected.They were assessed with Kessler Psychological Distress Scale (K10),Connor-Davidson Resilience Scale (CD-RISC-10),Perceived Social Support Scale (PSSS)and Sim-plified Coping Style Questionnaire (SCSQ)for the evaluation of psychological distress,resilience,perceived social support and the coping style respectively.Ordinal logistic regression was used to identify the related factors of psy-chological distress.Results:The mean score of K10 was (24.7 ±6.7),91.8% (528 /575)of telephone operators had psychological distress.Specifically,24.5%(141 /575)had mild psychological distress,45.4% (261 /575)had moderate psychological distress,21.9% (126 /575)had severe psychological distress.Ordinal logistic regression a-nalysis indicated that the ones with good economic conditions (OR =1.74,95%CI:1.15 -2.63),higher level of re-silience (OR =1.13,95%CI:1.10 -1.17)and other social support (OR =1.07,95%CI:1.02 -1.12)had milder psychological distress;while with negative coping style (OR =0.29,95%CI:0.20 -0.41)had more severe psycho-logical distress.Conclusion:It suggested that the prevalence rate of psychological distress among telephone opera-tors is high.Poor economic conditions,lower level of resilience and social support,and negative coping style might be the related factors of psychological distress.