1.Clinical analysis of hospitalized patients with distal deep venous thrombosis
Shengchun ZHU ; Chunlan HU ; Li GONG ; Jianying XIE
Chinese Journal of General Practitioners 2022;21(6):554-559
Objective:To analyze the clinical characteristics of hospitalized patients with distal deep venous thrombosis (DDVT).Methods:Medical records of patients without DDVT at admission and discharged from January 1,2021 to June 30,2021, were retrospectively reviewed. During the pre-hospitalization and hospitalization period the ultrasonography was performed for detection of DDVT. The venous thromboembolism (VTE) risk scores were evaluated with Caprini scale for surgical patients, and evaluated with Padua scalefor nonsurgical patients.Results:A total of 16 400 patients, 8 827 males and 7 573 females with a mean age of (63.8±14.2) years (14 to 101 years) were enrolled, among whom DDVT occurred in 1 193 patients (DDVT group), including 73 cases developed during pre-hospitalization; meanwhile 124 patients were diagnosed as deep vein thrombosis(DVT), and 15 083 patients without DVT served as non-DDVT group. The detection rate of DDVT in patients with medium/high VTE risk scorewas significantly higher than thatin low-risk patients [12.8% (982/7 644) vs. 2.4% (211/8 756), χ2=659.10, P<0.001]. The detection rate of DDVT for medium/high VTE risk score group was the highest in emergency intensive care unite and intensive care unite(ICU; 34.3%, 68/198), followed by that in departments of rehabilitation (25.7%, 45/175), neurology (19.9%,37/186), neurosurgery(19.4%,83/428), respiratory medicine(19.0%,56/295) and orthopedics (15.4%, 378/2 451).The detection rate of DDVT increased with age.The lowest detection rate was found in the age group 14 to 40 years, for low VTE risk score group it was 0.5%(4/770), for the medium/high VTE risk score group it was 3.0%(11/362, χ2=10.10, P<0.001).In patients over 75 years of age, the detection rate of DDVT was 5.2%(85/1 624) in low VTE risk score group, and 18.0%(389/2 158) in medium/high VTE risk score(χ2=138.82, P<0.001).The mean age of the DDVT group was older than that of non-DDVT group [(71.0±12.1) vs. (63.2±14.2) years, t=21.14, P<0.001]. The abnormality rate of D-dimer level in DDVT patients was significantly higher than that in non-DDVT patients [71.4%(813/1 138) vs. 25.4%(3 492/13 770), χ2=1 086.80, P<0.001]. The median length of hospital stay was significantly longer than that of the non-DDVT group [11.0 (8.0, 19.0) vs. 6.0 (4.0, 10.0)d, Z=-26.67, P<0.001].The risk factors for non-surgical DDVT patients were age, bed rest for ≥3 d, and acute infection; while the risk factors for surgical DDVT patients were age, fracture in hip, pelvis or lower limb, bedridden for ≥3 d and body mass index (BMI)>25 (kg/m 2). Conclusion:The detection rate of DDVT is higher in hospitalized patients, especially for those in ICU and rehabilitation department, and those over 75 years old with high VTE score. Advanced age, fracture or immobilization, and long-term bed rest are the main risk factors for DDVT.
2.Application of personalized lateral decubitus pillow for patients with cervical spine surgery
Chunlan? GONG ; Guoying WEN ; Cuiyan LONG ; Xinqian XIE ; Guanyi FANG ; Fujuan ZHOU
Chinese Journal of Modern Nursing 2015;21(5):599-601
Objective To explore the application effect of personalized lateral decubitus pillow for patients with cervical spine surgery. Methods A totals of 106 patients after cervical spine surgery were recruited and randomly divided into control group (48 cases) and experimental group (58 cases). Patients in the control group used the common pillow when patients lay lateral position-the height of pillow equal to shoulder cheekbone breadth, while experimental group used the personalized lateral decubitus pillow which supported suspended occipitalis and the height of pillow adjusted by individual. The comfort score, incision pain score and last time for lateral position of all patients were compared. Results The comfort score of the experimental group was significantly higher than that of the control group during the first day, second day and the third day after surgery [(66. 3 ± 4. 8) vs (63. 4 ± 3. 5), (68. 4 ± 5. 3) vs (65. 1 ± 4. 6), (71. 3 ± 4. 8) vs (68. 3 ± 4. 4);t=3. 461,3. 473,3. 270, respectively; P <0. 05]. The incision pain score of the experimental group was significantly lower than that of the control group during the first day, second day and the third day after surgery [(5.09±1.33) vs(5.88±1.29),(4.78±1.30) vs(5.52±1.09),(4.33±1.13) vs(5.06±1.06);t=3. 127,3. 157,3. 427, respectively;P<0. 05]. The last time of the experimental group for lateral position were longer than that of control group [(88. 6 ± 15. 2) min vs (79. 3 ± 14. 1) min; t = -3. 239,P =0. 002]. Conclusions It can increase the comfort score, extend the last time for lateral position and lessen incision pain to use the individuation lateral position pillow for patients after cervical spine surgery.
3.Correlation analysis of the early maternal breastfeeding self-efficacy and social support in Yanbian area
Hui CAO ; Xin YAN ; Chunlan GONG ; Mingren LIU
Chinese Journal of Modern Nursing 2014;20(10):1172-1174
Objective To describe the general demographic characteristics of the breastfeeding self -efficacy, the differences in social support and study their correlation .Methods Convenience selection method was adopted from August to December , 2012 , and 154 cases joined the study .Research tools included a demographic characteristics questionnaire , the Breastfeeding Self-Efficacy Scale , and the Social Support Scale . SPSS 17.0 was used for data analysis .Results The new mothers in different general demographic characteristics had no significant differences in self-efficacy (P>0.05).The scores of social support of new mothers with middle school education background , junior college background and university background were (39.34 ±4.17), (42.16 ±5.55) and (46.85 ±4.96), respectively.The difference was significant (F=13.940, P<0.01).The scores of social support of new mothers with different working situations was significant different ( t =2.253, P <0.05).The mean score of breastfeeding self-efficacy and social support of new mothers were (110.71 ±19.53) and (42.73 ±5.73), respectively, with a positive correlation (r=0.235, P<0.01).The total score of social support and the score of skills and mental activity , and the scores of subjective feeling of social support and self-efficacy and the score of mental activity had a positive correlation (r=0.231, 0.243, 0.244, 0.230, respectively; P<0.01).Conclusions The early maternal breastfeeding self-efficacy scores are high and the social support is in good condition .Both the Han and the Korean new mothers have gained an excellent self-efficacy.
4.Liposomal paclitaxel in combination with cisplatin as a first line of chemotherapy in treatment of advanced NSCLC with regional lymph node metastasis:A randomized controlled trial
Hu LUO ; Jingxiang YANG ; Liang GONG ; Yongfeng CHEN ; Chunlan TANG ; Heping YANG ; Wei XIONG ; Jianlin HU ; Ying HUANG ; Guangming LUO ; Hailing DUAN ; Xiangdong ZHOU
China Oncology 2013;(12):995-1000
Background and purpose: Regional lymph node metastasis was significantly associated with the prognosis of patients with non-small cell lung cancer (NSCLC). This study was designed to compare paclitaxel liposome plus cisplatin (LP) with gemcitabine and cisplatin (GP) in patients with regional lymph node metastasis of advanced NSCLC as a ifrst-line treatment. Methods:A total of 55 patients were randomly assigned to receive either liposomal paclitaxel (175 mg/m2) and cisplatin (75 mg/m2) or gemcitabine (1 000 mg/m2) and cisplatin (75 mg/m2) every 3 weeks. Results:Objective response rate (ORR) of lung primary foci was 37.9%in the LP arm and 30.8%in the GP arm (P>0.05) and the disease control rate (DCR) was 91.3%and 80.8%respectively (P>0.05);ORR of regional metastasis lymph node was higher in the LP arm (44.8%vs 15.4%, P<0.05).There was no signiifcant difference in DCR (93.1%vs 73.1%, P=0.101), although slight trends favoring paclitaxel liposome were seen;There was signiifcant difference in median overall survival (17.0 vs 12.0 months, P<0.05). LP was associated with significantly less thrombocytopenia and gastrointestinal side effects (P<0.05), but no signiifcant difference was observed in hyphemia, leucopenia, hepatotoxicity, renal toxicity and allergic reactions (P>0.05). Conclusion: Liposomal paclitaxel plus cisplatin is superior to gemcitabine plus cisplatin with less toxicity and better tolerated, it deserves further research and clinic application for patients with regional lymph node metastasis of advanced NSCLC.
5.Extended Functions and Design of Medical Data Integration Platform
Gong CHEN ; Jie YU ; Chunlan YU ; Yun SUN
Chinese Medical Equipment Journal 2009;30(7):59-61
Obiective To expand the functions of the original data integration platform combined business process to achieve cross-system integration in hospital, Methods On the basis of efficient data interaction for every medical information system in hospital, more related function modules for the DIP were added. Results The new function modules can satisfy DIP multiple needs in the hospital daily work and make the DIP more powerful. Conclusion The applicability and rationality of DIP are improved by extended function.

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