1.Clinical efficacy of infrared thermal imaging technology-assisted CT-guided spinal dorsal root ganglion pulse radiofrequency combined with ozone therapy for the treatment of acute herpes zoster
Guiling WANG ; Chunman WANG ; Qian GAO ; Chuansui DU ; Lin LI
Journal of Interventional Radiology 2025;34(5):482-486
Objective To investigate the clinical efficacy of infrared thermal imaging technology-assisted CT-guided spinal dorsal root ganglion pulse radiofrequency(DRG-PRF)combined with ozone therapy in treating patients with acute herpes zoster.Methods A total of 128 patients with acute herpes zoster,who were admitted to Hengshui Municipal People's hospital between March 2021 and March 2024 to receive treatment,were enrolled in this study.Using SPSS,the patients were simply and randomly divided into the control group(n=64,receiving conventional DRG-PRF combined with ozone therapy)and the study group(n=64,receiving infrared thermal imaging technology-assisted CT-guided DRG-PRF combined with ozone therapy).The patients were followed up for 3 months.The pain numerical score(NRS),Pittsburgh Sleep Quality Index(PSQI),36-item health survey Summary Form(SF-36)score,skin temperature difference(ΔT),and adverse reactions were compared between the two groups.Results Compared with the control group,in the study group the postoperative one-day,3-day,5-day,7-day,and one-month NRS scores were lower(P<0.05);the postoperative one-month,2-month and 3-month PSQI scores and the ΔT were lower,and the postoperative one-month,2-month and 3-month SF-36 scores were higher(P<0.05).No statistically significant difference in the incidence of adverse reactions existed between the two groups(P>0.05).Conclusion In treating patients with acute herpes zoster,infrared thermal imaging technology-assisted CT-guided DRG-PRF combined with ozone therapy can significantly relieve pain,improve quality of sleep and life of patients,reduce the skin temperature difference on the affected side,besides,this technique carries certain clinical safety.
2.Clinical curative effect of CT-guided dorsal root ganglion pulsed radiofrequency combined with ozone injection for chronic postherpetic neuralgia
Guiling WANG ; Chunman WANG ; Lin LI ; Qian GAO ; Chuansui DU
Journal of Interventional Radiology 2024;33(12):1330-1334
Objective To evaluate the clinical curative effect of CT-guided dorsal root ganglion pulsed radiofrequency(DRG-PRF)combined with ozone injection in treating patients with chronic postherpetic neuralgia(PHN).Methods A total of 300 patients with chronic PHN,who were admitted to the Hengshui Municipal People's Hospital of China from December 2020 to August 2023,were enrolled in this study.Using random digital table method,the patients were divided into observation group(n=150,receiving ozone injection+CT-guided DRG-PRF)and control group(n=150,receiving ozone injection alone).The curative effect,infrared thermal imaging index(skin temperature difference between skin lesion area and the corresponding healthy side,i.e.ΔT),sleep quality,pain degree(determined by numerical rating scale,NRS),and pain/inflammatory factors including prostaglandin E2(PGE2),substance P(SP),interleukin-6(IL-6),interleukin-1β(IL-1β)were compared between the two groups.Results The total response rate in the observation group was 92.67%(139/150),which was higher than 83.33%(125/150)in the control group,the difference was statistically significant(P<0.05).At one d,3 d,7 d,one month and 3 months after treatment,the scores of ΔT,PSQI and NRS in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The levels of serum PGE2,SP,IL-6 and IL-1β in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion For the treatment of chronic PHN,CT-guided DRG-PRF combined with ozone injection has reliable clinical effect,it can effectively promote the recovery of skin damage,improve sleep quality,relieve pain,and regulate the levels of pain and inflammatory factors.

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