Objective To observe the effects of psychological pretreatment on the stress reaction of simulated fast buoyancy ascent escape in rats. Methods Forty healthy rats were randomly divided into 4 groups:the control group, the psychological stress group, the fast compression and decompression group, and the psychological stress pretreatment plus fast compression and decompression group. By developing the fast buoyancy ascent escape rat model with fast compression and decompression in a closed cabin, the effects of psychological pretreatment on the stress reaction were observed in the course of ascent. Results Hear t rate of the animals in the psychological pretreatment stress group was significantly higher than that in the control group (P＜0. 05), and the expression of serum TNF-α was significantly lower than that in the control group (P ＜ 0.05 ). Conclusions Psychological factor seemed to have positive effects on the stress reaction of the simulated fast buoyancy ascent escape in rats.

Objective To explore effective approaches to the improvement of the academic level of the Journal through analysis of the fund papers published in the Chinese Journal of Nautical Medicine and Hyperbaric Medicine. Methods Bibliometrics was used to analyze the amount of fund papers published, the percentage of fund papers, the rate of financial support, subject distributions, the authors institutions and regions,and co-authors of the sponsored articles in the journal from 2006 to 2010. Results Published from 2006 to 2010 were 194 fund papers which accounted for 21.4% of the total number of articles published in the Journal. Of all the fund papers, most were sponsored or supported by provincial or ministerial foundations, accounting for 86. 1%. The fund papers come from 51 institutions, and 47 papers were contributed by authors from colleges and universities, 34 articles were from research institutes, 113 articles were from hospitals. Most articles had several co-authors, the average number of authors per paper was 5.9, and the papers having 4-9 authors accounted for 82.0% of the total fund papers. Identified as the first author were 7 core authors who published no less than 3 articles. There were 9 core institutions which accounted for 17. 6% of the total outgoing institutions, and published a total of 134 papers, which accounted for 69. 1% of the total fund papers. The first 4 core institutions placed in order of importance were the Naval Medicine Research Institute, the Second Military Medical University, the Navy General Hospital and the Beijing Chaoyang Hospital. Conclusions The Chinese Journal of Nautical Medicine and Hyperbaric Medicine is the core journal in the discipline of nautical medicine and hyperbaric medicine. The fund papers published in the Journal could reflect the academic level in this field. In order to improve the academic level of the Journal and promote further development of the discipline, efforts should be made on subject selection and planning. In addition, a database of core authors and experts of core outgoing institutions should be established.

Objective To observe the effects of psychological pretreatment on the stress reaction of simulated fast buoyancy ascent escape in rats. Methods Forty healthy rats were randomly divided into 4 groups:the control group, the psychological stress group, the fast compression and decompression group, and the psychological stress pretreatment plus fast compression and decompression group. By developing the fast buoyancy ascent escape rat model with fast compression and decompression in a closed cabin, the effects of psychological pretreatment on the stress reaction were observed in the course of ascent. Results Hear t rate of the animals in the psychological pretreatment stress group was significantly higher than that in the control group (P＜0. 05), and the expression of serum TNF-α was significantly lower than that in the control group (P ＜ 0.05 ). Conclusions Psychological factor seemed to have positive effects on the stress reaction of the simulated fast buoyancy ascent escape in rats.

Objective To explore effective approaches to the improvement of the academic level of the Journal through analysis of the fund papers published in the Chinese Journal of Nautical Medicine and Hyperbaric Medicine. Methods Bibliometrics was used to analyze the amount of fund papers published, the percentage of fund papers, the rate of financial support, subject distributions, the authors institutions and regions,and co-authors of the sponsored articles in the journal from 2006 to 2010. Results Published from 2006 to 2010 were 194 fund papers which accounted for 21.4% of the total number of articles published in the Journal. Of all the fund papers, most were sponsored or supported by provincial or ministerial foundations, accounting for 86. 1%. The fund papers come from 51 institutions, and 47 papers were contributed by authors from colleges and universities, 34 articles were from research institutes, 113 articles were from hospitals. Most articles had several co-authors, the average number of authors per paper was 5.9, and the papers having 4-9 authors accounted for 82.0% of the total fund papers. Identified as the first author were 7 core authors who published no less than 3 articles. There were 9 core institutions which accounted for 17. 6% of the total outgoing institutions, and published a total of 134 papers, which accounted for 69. 1% of the total fund papers. The first 4 core institutions placed in order of importance were the Naval Medicine Research Institute, the Second Military Medical University, the Navy General Hospital and the Beijing Chaoyang Hospital. Conclusions The Chinese Journal of Nautical Medicine and Hyperbaric Medicine is the core journal in the discipline of nautical medicine and hyperbaric medicine. The fund papers published in the Journal could reflect the academic level in this field. In order to improve the academic level of the Journal and promote further development of the discipline, efforts should be made on subject selection and planning. In addition, a database of core authors and experts of core outgoing institutions should be established.

Objective To observe the effects of MIP-2 antibody on the inflammation in lung tissue of pulmonary oxygen toxicity in mice.Methods The pulmonary oxygen toxicity model were duplicated by breathing hyperbaric oxygen,and 40 mice were randomly divided into 5 groups:control group.0.2 MPa-224 min group,0.2 MPa-289 min group,normal O2 group,and antibody group.Mice in the control group breathed normal air,the normal O2 group breathed N2-O2 gas mixture,in which O2 partial pressure was same to that in the atmosphere.The antibody group breathed MIP-2 antibody aerosol.The expression of MIP-2 in the lung was measured by IHC.Results The MIP-2 abundance of HBO treated groups was significantly higher than that of the control group (P<0.05),whereas the expression of MIP-2 of the normal O2 group was not significantly higher than that of the control group (P>0.05).MIP-2 antibody may alleviate inflammation lesion of pulmonary oxygen toxicity in mice.Conclusions Pulmonary oxygen toxicity might elevate expression of MIP-2,and MIP-2 antibody alleviate inflammation lesion of pulmonary oxygen toxicity in mice.

Objective To observe the effects of MIP-2 antibody on the inflammation in lung tissue of pulmonary oxygen toxicity in mice.Methods The pulmonary oxygen toxicity model were duplicated by breathing hyperbaric oxygen,and 40 mice were randomly divided into 5 groups:control group.0.2 MPa-224 min group,0.2 MPa-289 min group,normal O2 group,and antibody group.Mice in the control group breathed normal air,the normal O2 group breathed N2-O2 gas mixture,in which O2 partial pressure was same to that in the atmosphere.The antibody group breathed MIP-2 antibody aerosol.The expression of MIP-2 in the lung was measured by IHC.Results The MIP-2 abundance of HBO treated groups was significantly higher than that of the control group (P<0.05),whereas the expression of MIP-2 of the normal O2 group was not significantly higher than that of the control group (P>0.05).MIP-2 antibody may alleviate inflammation lesion of pulmonary oxygen toxicity in mice.Conclusions Pulmonary oxygen toxicity might elevate expression of MIP-2,and MIP-2 antibody alleviate inflammation lesion of pulmonary oxygen toxicity in mice.

Objective Through statistical analyses of the distribution characteristics of international monographers on hyperbaric oxygenation,collected by MEDLINE (1998 -2007 ),the number of monographs from 60 countries was compared and analyzed.With the above work done,the most important corporate authors and core authors were identified.

Objective Through statistical analyses of the distribution characteristics of international monographers on hyperbaric oxygenation,collected by MEDLINE (1998 -2007 ),the number of monographs from 60 countries was compared and analyzed.With the above work done,the most important corporate authors and core authors were identified.