1.Translation and validation of the health-related quality of life in stroke patients - 26 (HRQoLISP-26) scale into Filipino for Filipino adult stroke Patients.
Shanelle Katrina N. TAN ; Portia Margarita D. SIMSUANGCO ; Fatima Mae S. SINGSON ; Joselle T. SINSON ; Celina Therese R. SOLOMON ; Arnold Christopher P. SORIANO ; Stephen Lorenzo P. SULAY ; Mikhael Thaddeus S. SUPE ; Rafael Alfonso S. SYFU ; Althea Jannary C. TALENS ; Ian Cedric D. TAN ; Jan Tyrone CABRERA ; Wennielyn F. FAJILAN ; Elenita MENDOZA ; John Dale TROGO
Journal of Medicine University of Santo Tomas 2026;10(1):1895-1903
INRODUCTION
Stroke is one of the top five leading causes of disability in the Philippines. It has a significant impact on the quality of life (QoL) of patients, particularly in the functional and psycho-emotional aspects. Thus, it is important to understand the health-related quality of life in stroke patients (HRQoLISP), which focuses on the clinical impact of the disease and disability. The assessment of a stroke patient’s QoL is prognostically significant as it can predict a patient’s treatment success and survival.
OBJECTIVEThis study aims to translate the HRQoLISP-26 into Filipino and assess its content validity for Filipino adult stroke patients.
METHODOLOGYThe HRQoLISP-26 was translated into Filipino using a forward translation protocol and an expert analyzed the forward translation. Selected expert committee members reviewed the first version to assess for content validity and the questionnaire was modified accordingly. The content validity index (CVI) was used for content validity.
RESULTSMajority of the revisions made were done to improve the semantic and grammatical accuracy of items in the Filipino version of the HRQoLISP-26. Only a few items had no revisions implemented. No revisions were done in the final version of the translated questionnaire as each item had a CVI of 1 indicating that it has good content validity.
CONCLUSIONThe Filipino translated HRQoLISP-26 questionnaire is a validated questionnaire that allows assessment of a stroke survivor’s QoL.
Quality Of Life ; Patients ; Life ; Health ; Adult ; Stroke
2.Clinical guidance on endoscopic management of colonic polyps in Singapore.
Tiing Leong ANG ; Jit Fong LIM ; Tju Siang CHUA ; Kok Yang TAN ; James Weiquan LI ; Chern Hao CHONG ; Kok Ann GWEE ; Vikneswaran S/O NAMASIVAYAM ; Charles Kien Fong VU ; Christopher Jen Lock KHOR ; Lai Mun WANG ; Khay Guan YEOH
Singapore medical journal 2022;63(4):173-186
Colonoscopy with endoscopic resection of detected colonic adenomas interrupts the adenoma-carcinoma sequence and reduces the incidence of colorectal cancer and cancer-related mortality. In the past decade, there have been significant developments in instruments and techniques for endoscopic polypectomy. Guidelines have been formulated by various professional bodies in Europe, Japan and the United States, but some of the recommendations differ between the various bodies. An expert professional workgroup under the auspices of the Academy of Medicine, Singapore, was set up to provide guidance on the endoscopic management of colonic polyps in Singapore. A total of 23 recommendations addressed the following issues: accurate description and diagnostic evaluation of detected polyps; techniques to reduce the risk of post-polypectomy bleeding and delayed perforation; the role of specific endoscopic resection techniques; the histopathological criteria for defining endoscopic cure; and the role of surveillance colonoscopy following curative resection.
Adenoma/surgery*
;
Colonic Neoplasms/surgery*
;
Colonic Polyps/surgery*
;
Colonoscopy/methods*
;
Colorectal Neoplasms/pathology*
;
Humans
;
Singapore
;
United States
3.Impact of COVID-19 on Endoscopy Training: Perspectives from a Global Survey of Program Directors and Endoscopy Trainers
Shivakumar VIGNESH ; Amna Subhan BUTT ; Mohamed ALBORAIE ; Bruno Costa MARTINS ; Alejandro PISCOYA ; Quang Trung TRAN ; Damien Tan Meng YEW ; Shahriyar GHAZANFAR ; Pezhman ALAVINEJAD ; Edna KAMAU ; Ajay M VERMA ; Robin B MENDELSOHN ; Christopher KHOR ; Alan MOSS ; David Wei Chih LIAO ; Christopher S HUANG ; Franklin C TSAI
Clinical Endoscopy 2021;54(5):678-687
Background/Aims:
The coronavirus disease of 2019 (COVID-19) pandemic has impacted the training of medical trainees internationally. The aim of this study was to assess the global impact of COVID-19 on endoscopy training from the perspective of endoscopy trainers and to identify strategies implemented to mitigate the impact on trainee education.
Methods:
Teaching faculty of gastroenterology (GI) training programs globally were invited to complete a 36-question web-based survey to report the characteristics of their training programs and the impact of COVID-19 on various aspects of endoscopy training, including what factors decisions were based on.
Results:
The survey response rate was 52.6% (305 out of 580 individuals); 92.8% reported a negative impact on endoscopy training, with suspension of elective procedures (77.1%) being the most detrimental factor. Geographic variations were noted, with European programs reporting the lowest percentage of trainee participation in procedures. A higher proportion of trainees in the Americas were allowed to continue performing procedures, and trainers from the Americas reported receiving the greatest support for endoscopy teaching.
Conclusions
This study demonstrated that the COVID-19 pandemic has had a significant negative impact on GI endoscopy training internationally, as reported by endoscopy trainers. Focus-optimizing endoscopy training and assessment of competencies are necessary to ensure adequate endoscopy training.
4.Impact of COVID-19 on Endoscopy Training: Perspectives from a Global Survey of Program Directors and Endoscopy Trainers
Shivakumar VIGNESH ; Amna Subhan BUTT ; Mohamed ALBORAIE ; Bruno Costa MARTINS ; Alejandro PISCOYA ; Quang Trung TRAN ; Damien Tan Meng YEW ; Shahriyar GHAZANFAR ; Pezhman ALAVINEJAD ; Edna KAMAU ; Ajay M VERMA ; Robin B MENDELSOHN ; Christopher KHOR ; Alan MOSS ; David Wei Chih LIAO ; Christopher S HUANG ; Franklin C TSAI
Clinical Endoscopy 2021;54(5):678-687
Background/Aims:
The coronavirus disease of 2019 (COVID-19) pandemic has impacted the training of medical trainees internationally. The aim of this study was to assess the global impact of COVID-19 on endoscopy training from the perspective of endoscopy trainers and to identify strategies implemented to mitigate the impact on trainee education.
Methods:
Teaching faculty of gastroenterology (GI) training programs globally were invited to complete a 36-question web-based survey to report the characteristics of their training programs and the impact of COVID-19 on various aspects of endoscopy training, including what factors decisions were based on.
Results:
The survey response rate was 52.6% (305 out of 580 individuals); 92.8% reported a negative impact on endoscopy training, with suspension of elective procedures (77.1%) being the most detrimental factor. Geographic variations were noted, with European programs reporting the lowest percentage of trainee participation in procedures. A higher proportion of trainees in the Americas were allowed to continue performing procedures, and trainers from the Americas reported receiving the greatest support for endoscopy teaching.
Conclusions
This study demonstrated that the COVID-19 pandemic has had a significant negative impact on GI endoscopy training internationally, as reported by endoscopy trainers. Focus-optimizing endoscopy training and assessment of competencies are necessary to ensure adequate endoscopy training.
5.Percutaneous transluminal angioplasty of transplant renal artery stenosis.
Lee Lian CHEW ; Bien Soo TAN ; Krishna KUMAR ; Maung Myint HTOO ; Kok Seng WONG ; Christopher W S CHENG ; Terence K B TEO ; Farah Gillani IRANI ; Hui Lin CHOONG ; Kiang Hiong TAY
Annals of the Academy of Medicine, Singapore 2014;43(1):39-43
INTRODUCTIONThis study aimed to assess the outcome of percutaneous transluminal angioplasty (PTA) as the primary treatment for transplant renal artery stenosis (TxRAS).
MATERIALS AND METHODSA retrospective review of PTA of TxRAS from April 1999 to December 2008 was performed. Twenty-seven patients (17 males (M):10 females (F)) with the mean age of 49.5 years underwent PTA of TxRAS in the review period. Indications for PTA were suboptimal control of hypertension (n=12), impaired renal function (n=6) and both suboptimal control of hypertension and impaired renal function (n=9). All patients had doppler ultrasound scans prior to their PTA. In addition, 5 of these patients had computed tomography angiography (CTA) and another 7 had magnetic resonance angiography (MRA) evaluation. Mean follow-up period was 57.0 months (range, 7 to 108 months).
RESULTSThe stenotic lesions were located proximal to the anastomosis (n=2), at the anastomosis (n=15), and distal to the anastomosis (n=14). Technical success rate was 96.3%. One case was complicated by extensive dissection during PTA, resulting in subsequent graft failure. The overall clinical success rate was 76.9%. Seven out of 26 patients had restenoses (26.9% of cases). These were detected at a mean of 14.3 months post angioplasty (range, 5 to 38 months). All 7 patients underwent a second PTA successfully. Three of these patients required more than 1 repeat PTA.
CONCLUSIONPTA is safe and effective in the management of symptomatic TxRAS and should be the primary treatment of choice. Close surveillance for restenosis is required and when diagnosed, re-angioplasty can be performed.
Adult ; Angioplasty ; Female ; Humans ; Kidney Transplantation ; Male ; Middle Aged ; Postoperative Complications ; surgery ; Renal Artery Obstruction ; surgery ; Retrospective Studies ; Time Factors
6.The use of n-butyl-2 cyanoacrylate as an embolic agent in the minimally invasive treatment of renal arteriovenous malformations.
Pei Ghim POH ; Bien Soo TAN ; Seng Choe THAM ; Kiang Hiong TAY ; Austin M M HTOO ; Michael B K LIN ; Christopher W S CHENG ; Tsung Wen CHONG ; Keong Tat FOO ; Winston E H LIM
Annals of the Academy of Medicine, Singapore 2013;42(4):207-209
Adult
;
Arteriovenous Malformations
;
therapy
;
Embolization, Therapeutic
;
methods
;
Enbucrilate
;
therapeutic use
;
Female
;
Humans
;
Kidney
;
blood supply
;
Male
;
Middle Aged
7.Prevalence and Awareness of Lower Urinary Tract Symptoms among Males in the Outpatient Clinics of Universiti Kebangsaan Malaysia Medical Centre
Christopher Ho CK ; Praveen S ; Goh EH ; Tan GH ; Badrulhisham B ; Zulkifli MZ ; Khoo HW ; Su XV ; Ng JY ; Chong LL ; Lim DW ; Chen ES ; Teoh SY
Medicine and Health 2011;6(2):98-106
This study aims to determine the prevalence of lower urinary tract symptoms (LUTS) and level of awareness among male outpatients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC). A questionnaire consisting of demographic data, questions related to knowledge, attitude and practice on BPH and the International Prostate Symptom Score (IPSS) was used for this study. Uroflowmetry and bladder scan were used to evaluate the function of the urinary tract and severity of BPH. Urine dipstick was done for glycosuria, proteinuria and haematuria. A total of 220 respondents were surveyed. The prevalence of moderately and severely symptomatic LUTS was 42.7%. The most commonly reported LUTS were nocturia (78.2%), frequency (58.2%) and incomplete emptying (44.6%). The prevalence of glycosuria, proteinuria and haematuria were 23.6%, 11.4% and 1.8% respectively. There was a significant association between increasing age with the severity of LUTS (p=0.005). Out of 102 respondents with voided urine volume greater than 150 mL, there was a significant decrease in maximum (Qmax) (p=0.039) and average (Qave) urine flow rates with every 10 years increase of age (p=0.001). The majority of respondents (59.5%) have heard of BPH before. Over 78.2% of the respondents would seek medical attention if they have LUTS with 15.9% saying they would seek traditional treatment. In conclusion, the prevalence of LUTS was high and the level of awareness was satisfactory.
8.Management of thrombotic thrombocytopenic purpura in metastatic prostate cancer with only endocrine therapy.
Ravindran KANESVARAN ; Colin PHIPPS ; Christopher W S CHENG ; Michelle M F CHAN ; Daphne KHOO ; Min Han TAN
Annals of the Academy of Medicine, Singapore 2010;39(7):580-582
Androgen Antagonists
;
therapeutic use
;
Anilides
;
therapeutic use
;
Antineoplastic Agents, Hormonal
;
therapeutic use
;
Bone Neoplasms
;
complications
;
secondary
;
Goserelin
;
therapeutic use
;
Humans
;
Male
;
Middle Aged
;
Nitriles
;
therapeutic use
;
Prostatic Neoplasms
;
complications
;
drug therapy
;
Purpura, Thrombotic Thrombocytopenic
;
drug therapy
;
etiology
;
Tosyl Compounds
;
therapeutic use
9.Outcomes of oral tongue cancer: does age matter?
Connie S P YIP ; Tze Choong CHARN ; Joseph T S WEE ; Terence W K TAN ; Christopher GOH ; Hiang Khoon TAN ; Kam Weng FONG
Annals of the Academy of Medicine, Singapore 2010;39(12):897-897
INTRODUCTIONThis is a retrospective study aimed to analyse the outcomes of oral tongue cancer with emphasis on young people.
MATERIALS AND METHODSPatients treated radically between 1998 and 2006 were included and categorised according to treatment modalities (Group A: Surgery, Group B: Surgery and adjuvant therapy, Group C: Definitive radiotherapy) and age groups (≤ 40 and > 40 years). Overall survival (OS), disease-free survival (DFS), locoregional relapse-free survival (LRS) and metastasis-free survival (MFS) were estimated using Kaplan-Meier method.
RESULTSThere were 123 patients with 32%, 53% and 15% in Group A, B and C, respectively. Of these, 17 patients (14%) were ≤40 years with 6 (15%), 8 (12%) and 3 (16%) young oral tongues in Group A, B and C, respectively. Five-year OS and DFS were 69%/72%, 41%/47% and 16%/9.5% for Group A, B and C, respectively. Young patients had similar survival as the older population with 5-year OS of 83%, 75% and 33% in Group A, B and C, as compared to the older patients (66%, 36% and 13%, respectively).
CONCLUSIONYoung oral tongue patients did not have worse outcomes.
Adult ; Age Factors ; Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Tongue Neoplasms ; therapy ; Treatment Outcome ; Young Adult
10.Laparoscopic partial nephrectomy for renal tumours: early experience in Singapore general hospital.
Mohd Zam Nor AZHARI ; Yeh Hong TAN ; Paul Anthony SUNGA ; Sidney K H YIP ; Christopher W S CHENG
Annals of the Academy of Medicine, Singapore 2009;38(7):576-575
INTRODUCTIONTo review the perioperative and short-term outcome of all laparoscopic partial nephrectomies (LPN) performed in a single institution.
MATERIALS AND METHODSThirteen consecutive patients who underwent LPN since the beginning of the programme in March 2002 to January 2008 were enrolled. Demographic, perioperative and follow-up data were retrospectively collected. Transperitoneal approach was used in all cases, and vascular control was achieved with the use of a laparoscopic Satinsky clamp or vascular tape. The tumour was excised using cold scissors. Transected intrarenal vessels were suture ligated and the parenchymal defect was closed primarily with absorbable suture over a bolster.
RESULTSThirteen patients underwent a total of 14 LPN. The median age of patients was 60 years (range, 41 to 77). The mean tumour size was 24 +/- 11.4 (2SD) mm. The mean operative time was 228 +/- 129 (2SD) minutes and median warm ischaemia time was 35 minutes (range, 24 to 68). Postoperatively, serum haemoglobin level decreased by a mean of 1.4 +/- 2.5 (2SD) gm/dL and serum creatinine increased by a mean of 22.5 +/- 25.8 (2SD) micromol/L. Twelve out of 13 (92%) patients achieved their baseline serum creatinine level within 1 month postoperatively. There was 1 open conversion (7%), and 2 patients (14%) required blood transfusion perioperatively. Two patients (14%) had transient fever postoperatively due to basal atelectasis. No other complications were encountered. Median patient hospital stay was 4 days (range, 2 to 10). Eleven out of 14 (79%) of the tumours were renal cell carcinoma (RCC). At a median follow-up of 12 months (range, 6 to 53), all except 1 patient with RCC were disease-free.
CONCLUSIONSOur experience has shown that laparoscopic partial nephrectomy is a safe, feasible technique in our centre for patients with small exophytic renal tumours. Patients can be discharged early with preservation of renal function and good early cancer control.
Adult ; Aged ; Carcinoma, Renal Cell ; surgery ; Female ; Hospitals, General ; Humans ; Kidney Neoplasms ; surgery ; Laparoscopy ; methods ; Length of Stay ; Male ; Middle Aged ; Nephrectomy ; methods ; Retrospective Studies ; Singapore


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