1.Perioperative emergency laparotomy pathway for patients undergoing emergency laparotomy: A propensity score matched study.
Joel Wen Liang LAU ; Janardhan BALIGA ; Faheem KHAN ; Ying Xin TEO ; Jonathan Ming Jie YEO ; Vincent Zhiwei YEOW ; Christine Xia WU ; Stephanie TEO ; Tracy Jia Hui GOH ; Philip IAU
Annals of the Academy of Medicine, Singapore 2024;53(12):713-723
INTRODUCTION:
Emergency laparotomy (EL) is associated with high morbidity and mortality, often exceeding 10%. This study evaluated the impact of the EMergency Laparotomy Audit (EMLA) interdisciplinary perioperative pathway on patient outcomes, hospital costs and length of stay (LOS) within a single centre.
METHOD:
A prospective cohort study was conducted from August 2020 to July 2023. The intervention team included specialist clinicians, hospital administrators and an in-hospital quality improvement team. Patients who underwent EL were divided into a pre-intervention control group (n=136) and a post-intervention group (n=293), and an 8-item bundle was implemented. Propensity scoring with a 1:1 matching method was utilised to reduce confounding and selection bias. The primary outcomes examined were LOS, hospitalis-ation costs and surgical morbidity, while secondary outcomes included 30-day mortality and adherence to the intervention protocol.
RESULTS:
The utilisation of the EMLA perioperative care bundle led to a significant reduction in surgical complications (34.8% to 20.6%, P<0.01), a decrease in LOS by 3.3 days (15.4 to 12.1 days, P=0.03) and lower hospitalisation costs (SGD 40,160 to 30,948, P=0.04). Compliance with key interventions also showed improvement. However, there was no difference in 30-day mortality.
CONCLUSION
This study offers insights on how surgical units can implement systemic perioperative changes to improve outcomes for patients undergoing emergency laparotomy.
Humans
;
Laparotomy/methods*
;
Propensity Score
;
Female
;
Male
;
Prospective Studies
;
Length of Stay/statistics & numerical data*
;
Middle Aged
;
Hospital Costs/statistics & numerical data*
;
Postoperative Complications/epidemiology*
;
Aged
;
Emergencies
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Perioperative Care/methods*
;
Critical Pathways
;
Singapore
;
Adult
2.The use of traditional Chinese medicine among breast cancer patients: implications for the clinician.
Kar Yong WONG ; Ern Yu TAN ; Juliana J C CHEN ; Christine TEO ; Patrick M Y CHAN
Annals of the Academy of Medicine, Singapore 2014;43(2):74-78
INTRODUCTIONTraditional Chinese Medicine or Traditional Complementary Medicine (TCM) is commonly used in our culture. There are several concerns regarding its use in patients undergoing conventional treatments for breast cancer. In this study, we aimed to evaluate the prevalence and pattern of TCM use among our breast cancer patients, and to identify patients who were most likely to choose TCM.
MATERIALS AND METHODSA total of 300 patients on active follow-up with Breast Service at Tan Tock Seng Hospital were interviewed using a structured questionnaire.
RESULTSA total of 35% (104 of 296) of patients reported using TCM. The majority of the patients were introduced to TCM by family and friends following the diagnosis of breast cancer. All except 3 patients continued with recommended conventional therapy although most did not inform their clinicians of TCM use. None of the patients reported any serious adverse events and 75% of them perceived a benefit from TCM use. Younger patients and those of Chinese ethnicity were more likely to use TCM (P <0.01 and P = 0.03 respectively). There was no significant difference in the dialect group, religious beliefs and educational level between the 2 groups (P >0.05).
CONCLUSIONTCM use is common among our breast cancer patients, particularly the younger women. However, most patients do not inform their clinicians of TCM use while on recommended conventional therapies. It is therefore important for clinicians to initiate discussions regarding TCM use in order to be aware of potential unwanted drug interactions.
Adult ; Aged ; Aged, 80 and over ; Breast Neoplasms ; therapy ; Female ; Humans ; Medical Oncology ; Medicine, Chinese Traditional ; utilization ; Middle Aged

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