1.Latest advances in intelligent orthopedic technology empowering combat trauma care
Chinese Journal of Trauma 2025;41(10):925-931
The landscape of modern warfare is undergoing profound transformation. With the large-scale, clustered application of high-kinetic weapon systems and intelligent munitions, combat trauma has exhibited distinct characteristics: diversified injury patterns, a significant increase in the proportion of complex injuries, a drastically shortened golden window for treatment, more stringent time-critical requirements, and highly fragmented allocation of medical resources. These emerging trends pose systemic challenges to traditional combat trauma care systems, highlighting deficiencies including delayed injury assessment, experience-dependent medical decision-making, and low efficiency in multi-link coordination. Intelligent technologies for combat trauma care, underpinned by artificial intelligence, the Internet of Things, robotics, and brain-computer interfaces, offer new pathways to address the limitations of traditional care systems. Starting from the new challenges in modern combat trauma care, the author elaborated on the application of intelligent orthopedics across key stages including pre-hospital, in-hospital, and post-hospital care, identified potential issues and countermeasures, aiming to provide theoretical and practical references for the development of an intelligent combat trauma care system.
2.Impact of gut microbiota dysbiosis on the healing of open limb fractures and corresponding intervention strategies: a review
Jianhui ZHU ; Yue MA ; Xingwen HAN
Chinese Journal of Trauma 2025;41(10):1008-1014
Open limb fractures, often caused by high-energy trauma, are frequently complicated by bacterial contamination, which can lead to delayed wound healing, impaired fracture union, or nonunion. The pathophysiological changes following the fractures can induce a series of alterations in the gut microbiota and their metabolites, resulting in gut microbial dysbiosis that adversely affects open limb fracture healing. Restoring the balance of the gut microbiota may help modulate immune responses and bone metabolism in patients, thereby promoting open fracture repair. Currently, there is no comprehensive summary of the relationship between gut microbiota and open limb fractures or the mechanisms by which gut microbiota interventions regulate fracture healing. Therefore, the authors reviewed the recent advances in the impact of gut microbiota dysbiosis on open limb fracture healing and corresponding intervention strategies, aiming to provide a reference for developing integrated fracture treatment approaches based on microbiome regulation.
3.Meta-analysis of effectiveness and safety of temperature-controlled therapy in patients with severe traumatic brain injury
Mengsha NIE ; Bo FENG ; Yue LU ; Qiongyu WU ; Minxiao LI ; Xiaogang CHEN ; Yuzhen ZHANG ; Liming CHENG
Chinese Journal of Trauma 2025;41(10):975-986
Objective:To evaluate the efficacy and safety of therapeutic temperature control in patients with severe traumatic brain injury (sTBI).Methods:The full-text databases of Chinese Medical Journal, China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, VIP Database, China Biomedical Database, PubMed, Embase, and Cochrane Library were searched for randomized controlled trials (RCTs) of hypothermia treatment and conventional treatment in patients with sTBI. The search period was from January 2016 to June 2025. Meta-analysis was performed using RevMan 5.3 software. The evaluation indicators included intracranial pressure before treatment, at 3 and 5 days after treatment, favorable prognosis rate and mortality rate within 6 months after treatment, and incidence of pulmonary infection, intracranial infection, epilepsy, acute gastrointestinal dysfunction, deep vein thrombosis, abnormal coagulation function, and arrhythmia during treatment; publication bias.Results:A total of 33 studies involving 3 322 patients were included, with 1 696 patients in the temperature treatment group and 1 626 in the conventional treatment group. There was no statistically significant difference in intracranial pressure between the two groups before treatment ( SMD=0, 95% CI -0.13, 0.14, P>0.05). However, at 3 and 5 days after treatment, the intracranial pressure was lower in the temperature treatment group than that in the conventional treatment group ( SMD=-2.29, 95% CI -2.76, -1.82, P<0.01; SMD=-2.66, 95% CI -3.43, -1.89, P<0.01). Within 6 months after treatment, the favorable prognosis rate was higher in the temperature treatment group than that in the conventional treatment group ( RR=1.41, 95% CI 1.32, 1.50, P<0.01), and mortality rate was lower than that in the conventional treatment group ( RR=0.64, 95% CI 0.55, 0.75, P<0.01). Compared with the conventional treatment group, the incidences of epilepsy and acute gastrointestinal dysfunction in the temperature treatment group were statistically reduced ( RR=0.33, 95% CI 0.13, 0.83, P<0.05; RR=0.43, 95% CI 0.25, 0.74, P<0.05). There were no statistically significant differences in the incidence of pulmonary infection ( RR=0.96, 95% CI 0.85, 1.08, P>0.05), intracranial infection ( RR=0.56, 95% CI 0.20, 1.56, P>0.05), deep vein thrombosis ( RR=0.93, 95% CI 0.69, 1.25, P>0.05), abnormal coagulation function ( RR=1.19, 95% CI 0.43, 3.31, P>0.05) or arrhythmia ( RR=0.51, 95% CI 0.23, 1.12, P>0.05) between the two groups. Egger′s test indicated the presence of publication bias and the results remained robust after trim and fill analysis. Conclusions:For patients with sTBI, temperature control therapy shows lowered intracranial pressure and mortality rate as well as improved favorable prognosis rate at 6 months posttreatment, and decreased incidence of epilepsy and acute gastrointestinal dysfunction during treatment, while reveals similar incidence of pulmonary infection, intracranial infection, deep vein thrombosis, abnormal coagulation function, and arrhythmia when compared with conventional treatment.
4.Comparative efficacy of hip hemiarthroplasty via the fracture line approach versus modified Harding approach in the treatment of unstable intertrochanteric fractures in the elderly
Bo SUN ; Kewei LI ; Shaohua WANG ; Aiguo WANG ; Wei MEI ; Jinliang WANG
Chinese Journal of Trauma 2025;41(8):746-753
Objective:To compare the efficacy of hip hemiarthroplasty via the fracture line approach versus modified Harding approach in the treatment of unstable intertrochanteric fractures in the elderly.Methods:A retrospective cohort study was conducted to analyze the clinical data of 79 elderly patients with unstable intertrochanteric fractures who were admitted to Zhengzhou Orthopaedic Hospital between July 2018 and February 2024, including 17 males and 62 females, aged 80-96 years [(84.0±9.6)years]. According to the AO classification, the fractures were classified as type A2 in 61 patients and type A3 in 18. All the patients underwent hip hemiarthroplasty, 33 of whom were treated via the fracture line approach (fracture line approach group) and 46 via the modified Harding approach (modified Harding approach group). The incision length, operation duration, intraoperative blood loss, blood transfusion volume, and weight-bearing time were documented. At 1 month, 3 months after surgery and at the last follow-up, hip function and pain were assessed using the Harris hip score and visual analogue scale (VAS). Postoperative dislocation rate, fracture nonunion rate, incidence of other complications (vascular injury, neurologic impairment, prosthesis loosening, lower extremity venous thrombosis, and surgical site infection) and 12-month mortality rate were recorded.Results:All the patients were followed up for 12-36 months [(18.0±5.1)months]. The operation duration and intraoperative blood loss were (68.2±8.4)minutes and (286.6±63.7)ml in the fracture line approach group, which were significantly shorter or less than (72.4±6.7)minutes and (321.3±76.2)ml in the modified Harding approach group ( P<0.05). However, there were no statistically significant differences in the incision length, blood transfusion volume or weight-bearing time between the two groups ( P>0.05). Harris hip scores and VAS scores at 1 month, 3 months, and at the last follow-up showed no significant differences between the two groups ( P>0.05). The dislocation rate was 0 in the fracture line approach group, superior to 13% in the modified Harding approach group ( P<0.05). There were no statistically significant differences in the fracture nonunion rate, incidence of other complications, or 12-month mortality rate between the two groups ( P>0.05). Conclusion:Compared with the modified Harding approach, hip hemiarthroplasty via the fracture line approach in the treatment of unstable intertrochanteric fractures in the elderly can shorten the operation time, reduce intraoperative blood loss, and lower the postoperative dislocation rate.
5.Characteristics of highly cited articles on spine and spinal cord injuries published in Chinese Journal of Trauma from 1985 to 2024
Hui DONG ; Liang YAN ; Baorong HE ; Guodong LIU
Chinese Journal of Trauma 2025;41(9):872-879
Objective:To analyze the characteristics of highly cited articles on spine and spinal cord injuries published in Chinese Journal of Trauma (hereinafter referred to as the "Journal") from 1985 to 2024. Methods:All the articles related to spine and spinal cord injuries published in the Journal from 1985 to 2024 were retrieved from the Wanfang Database and the articles with citation frequency ≥15 times were defined as highly cited, with the retrieval cut-off date of April 15, 2025. For articles related to spine and spinal cord injuries, the total publication count, number of cited articles, total citation frequency, average citation frequency per article, number of fund-supported articles were recorded and analyzed. For the highly cited articles among them, the total number of articles, types of literature, distribution periods, number of fund-supported articles, core authors, institution distribution, region distribution, frequency of and key words were also statistically analyzed.Results:From 1985 to 2024, the Journal published 1 182 articles on spinal and spinal cord injuries, of which 993 (84.01%) were cited, with a total citation frequency of 10 739 and an average of 10.81 citations per article. A total of 388 articles (32.83%) were supported by research funds. There were 184 highly cited articles on spinal and spinal cord injuries, with the following characteristics: (1) The most common type of highly cited literature was original articles (150 articles, 81.52%), while consensus and guideline articles achieved the highest average citation rate (44.75 citations per article). (2) The period 2015-2019 had the highest number of highly cited articles, accounting for 33.70%. (3) Fifty-four highly cited articles (29.35%) were supported by research funds, including 19 by national-level funds and 35 by funds of other levels. (4) Among the highly cited articles, 8 (4.35%) were authored by one person, and 176 (95.65%) were co-authored by two or more persons. Sixty-two authors who published ≥3 highly cited articles were identified as core authors. (5) A total of 123 highly cited articles (66.85%) were authored by researchers affiliated with a single institution, whereas 61 articles (33.15%) were the result of inter-institutional collaboration. Fifteen first-author institutions published≥3 highly cited articles. (6) Regions with ≥15 highly cited articles were Zhejiang Province (28 articles), Chongqing Municipality (23 articles), Guangdong Province (18 articles), Shaanxi Province (18 articles), Jiangsu Province (16 articles), and Shanghai Municipality (15 articles). (7) The top five key words in the highly cited articles were "spinal fractures" (71 times), "thoracic vertebrae" (45 times), "lumbar vertebrae" (44 times), "spinal cord injuries" (27 times), and "vertebroplasty" (27 times).Conclusions:Over the 40-year period, original articles constitute the majority of highly cited articles on spine and spinal cord injuries in the Journal, while consensus and guideline articles demonstrate the highest average citation frequency. Nearly 30% of the highly cited articles receive research funding support. Core authors and institutions show a relatively concentrated distribution, with spinal fractures, spinal cord injuries, and vertebroplasty emerging as research hotspots in the field.
6.Comparative efficacy of different warming measures during the perioperative period of robotic-assisted total hip arthroplasty for femoral neck fracture in elderly patients
Ru GU ; Lei LEI ; Xu XU ; Wen WANG ; Geng ZHANG ; Tianle FAN ; Shuixia LI
Chinese Journal of Trauma 2025;41(9):852-857
Objective:To compare the efficacy of active warming versus conventional warming during the perioperative period of robotic-assisted total hip arthroplasty (THA) for femoral neck fracture in elderly patients.Methods:A retrospective cohort study was conducted to analyze the clinical data of 312 elderly patients with femoral neck fracture who underwent robot-assisted THA at Second Affiliated Hospital of Xi ′an Jiaotong University from January 2024 to January 2025, including 196 males and 116 females, aged 65-89 years [(77.0±7.3)years]. Among them, 156 patients received standardized thermal management (active warming group), involving the administration of pre-warmed intravenous fluids and use of an inflatable warming blanket preoperatively, combined application of a forced-air warming system and warmed fluids intraoperatively, and transfer to a temperature-controlled ward combined with a foot circulatory compression device postoperatively. The other 156 patients received conventional warming with cotton quilts (conventional warming group), involving no administration of pre-warmed intravenous fluids preoperatively, use of warmed fluids intraoperatively, and transfer to a standard ward without the use of a foot circulatory compression device postoperatively. Core body temperature was compared between the two groups at 30 minutes preoperatively, 30 minutes intraoperatively, immediately postoperatively, and at 1 hour, 1 day, 5 days, and 7 days postoperatively. Changes in the coagulation function, including prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (APTT), and the inflammatory marker C-reactive protein (CRP) were assessed at 1 day preoperatively and at 1, 5, and 7 days postoperatively. Length of hospital stay and incidence of postoperative complications (incision infection, deep vein thrombosis, cardiac complications, and unplanned reoperations) were also recorded. Results:The core body temperature at 30 minutes intraoperatively, immediately postoperatively and at 1 hour postoperatively was (36.77±0.17)℃, (36.29±0.14)℃, and (36.35±0.14)℃ in the active warming group, significantly higher than (36.12±0.27)℃, (35.49±0.25)℃, and (35.67±0.29)℃ in the conventional warming group ( P<0.01). No significant differences in body temperature were observed between the two groups at 30 minutes preoperatively, at 1, 5, or 7 days postoperatively ( P>0.05). At 1 day postoperatively, the PT, TT and APTT were (8.5±1.3)seconds, (10.0±0.9)seconds and (24.8±2.3)seconds, significantly lower than (9.7±1.3)seconds, (12.1±1.5)seconds and (29.2±2.7)seconds in the conventional warming group ( P<0.01). There were no significant differences in PT, TT, APTT or CRP levels between the two groups at 1 day preoperatively or at 5 and 7 days postoperatively ( P>0.05). The CRP level at 1 day postoperatively was (8.0±3.0)mg/L in the active warming group, significantly lower than (13.5±3.2)mg/L in the conventional warming group ( P<0.05). There were no significant differences in CRP between the two groups at 1 day preoperatively or at 5 and 7 days postoperatively ( P>0.05). The average length of hospital stay was (12.2±1.4)days in the active warming group, significantly shorter than (14.9±1.4)days in the conventional warming group ( P<0.01). The perioperative complication rate was 6.4% (10/156) in the active warming group, significantly lower than 17.9% (28/156) in the conventional warming group ( P<0.01). Conclusion:For elderly patients with femoral neck fracture operated via robot-assisted THA, active warming during the perioperative period can more effectively maintain intraoperative normothermia, improve early postoperative coagulation function, reduce inflammatory response, shorten the length of hospital stay, and decrease complication rate when compared with conventional warming.
7.Characteristics of articles published in Chinese Journal of Trauma from 1985 to 2024
Mingchao ZHANG ; Yuqian YAO ; Xiaozhong ZHOU ; Guodong LIU
Chinese Journal of Trauma 2025;41(9):858-863
Objective:To analyze the characteristics of articles published in Chinese Journal of Trauma (hereinafter referred to as the "Journal") from 1985 to 2024, so as to provide insights for further clarifying its academic orientation and improving its quality. Methods:Data of articles published from 1985 to 2024 in the Journal were retrieved and extracted from the Wanfang Database (retrieval cut-off date: April 10, 2025). Statistical analysis was performed on the publication count, total citation frequency, number of cited articles, number of highly cited articles, proportion of fund-supported articles and their citation rate, distribution of article categories, author distribution, and keyword frequency.Results:Over the 40-year period, the Journal published a total of 10 687 articles, with the total citation frequency of 45 242. Among them, 7 497 articles (70.15%) were cited and 389 (3.64%) were highly cited. A total of 2450 articles (22.93%) were supported by research funds, with a citation rate of 80.29%. The clinical researoh column showed the largest number of publications, accounting for 7 996 articles (74.82%). First authors were distributed across 31 provincial-level regions, contributing 5 878 articles and 29 583 total citations. Thirty-five corresponding authors published more than 30 articles each, 17 of whom were from medical institutions in Chongqing Municipality. A total of 20 686 keywords were identified, with the top 5 being "fracture fixation, internal" (421 times), "craniocerebral injury" (395 times), "diagnosis" (359 times), "brain injury" (354 times), "spinal cord injury" (314 times).Conclusion:Over the 40-year period, the Journal has been characterized by a high overall academic influence despite a relatively low proportion of highly impactful publications, a substantial rate of fund-supported articles, a broad geographical distribution of first authors, with the most significant contributions coming from Chongqing Municipality, and a strong academic foundation in specialized disciplines such as orthopedics and neurosurgery.
8.Mechanism of electromagnetic neuromodulation technology in the treatment of spinal cord injury: a review
Chinese Journal of Trauma 2025;41(9):903-911
Spinal cord injury is a debilitating neurological condition associated with a high of disability rate, leading to impairments in motor, sensory, and autonomic functions. Current early interventions such as decompression and pharmacological treatments show limited efficacy, often resulting in lifelong deficits in sensory, motor, and other functions, which impose a significant burden on patients, their families, and the society. Recently, electromagnetic neuromodulation has emerged as a promising biomedical technology encompassing a variety of invasive and non-invasive techniques such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and epidural electrical stimulation (EES) that effectively promote neurological recovery in patients with spinal cord injury. However, research on electromagnetic neuromodulation in improving functional impairments after spinal cord injury remains limited, with still uncertain clinical outcomes, necessitating further investigation to clarify its underlying mechanisms. To this end, the authors reviewed recent advances in the mechanistic understanding of electromagnetic neuromodulation in the treatment of spinal cord injury, focusing on pain control, motor function recovery, blood pressure regulation, urogenital function improvement, alleviation of respiratory dysfunction, and reduction of limb spasticity, aiming to provide a reference for the clinical application and future development of electromagnetic neuromodulation technology.
9.Application of artificial intelligence in the diagnosis and treatment of spinal fracture and rehabilitation of spinal cord injury: a review
Haomin WANG ; Haifeng LIU ; Yibo ZHAO ; Wenxuan WANG ; Ningning XUE ; Bin ZHAO
Chinese Journal of Trauma 2025;41(9):912-917
Spinal trauma, primarily caused by high-energy external forces, predominantly manifest as vertebral fracture and spinal cord injury. These conditions are characterized by spinal pain, restricted mobility, and sensory and autonomic dysfunction, significantly compromising patients′ quality of life and life expectancy. Current diagnostic and therapeutic practices for spinal fracture remain susceptible to subjective clinical experience, resulting in misdiagnosis, underdiagnosis, and imprecise surgical execution. Similarly, the therapeutic efficacy of spinal cord injury rehabilitation is frequently limited by a lack of personalized treatment protocols. The growing integration of artificial intelligence (AI) in medicine presents novel opportunities to overcome these obstacles. By excelling in image interpretation, data analytics, clinical decision support, and personalized rehabilitation planning, AI has emerged as a prominent focus of modern research. To this end, the authors reviewed the research progress in the application of AI in the diagnosis and treatment of spinal fracture and rehabilitation of spinal cord injury, providing a reference for AI-assisted precision diagnosis and treatment of vertebral fracture and rehabilitation of spinal cord injury.
10.Construction and development of the trauma care system in China
Chinese Journal of Trauma 2025;41(2):133-137
The construction of the Chinese trauma care system has evolved from its initial stage to gradual development and expansion. In 2005, Peking University Traffic Medicine Center, which focused on traffic injury treatment and research, was established by Peking University People′s Hospital in collaboration with the emergency, trauma, and neurosurgery departments of Peking University First Hospital and Third Hospital. In 2010, Peking University Traffic Medicine Center led specialized scientific research projects and conducted pilot programs in multiple regions so that a regional closed-loop trauma care system which centered on comprehensive hospitals was established and a "Chinese model" for trauma care was developed. In 2016, China Trauma Rescue & Treatment Association was established so as to promote the construction of trauma care service system, the spread of the idea, and the information interconnection. In 2019, the National Center for Trauma Medicine was established and played a significant role in the clinical diagnosis and treatment, education and training, scientific research, and public rescue effort. Up to now, a multi-level trauma care system has been formed in china. In the paper, the authors elaborated the construction of the trauma care system and establishment of a national-level trauma care platform and foresaw the future development of trauma medicine in China.

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