Placenta，fetal heart and brain affect each other in the process of fetal growth. They are influenced by genetic，environmental，epigenetic and hemodynamic factors，and share several key developmental pathways. Fetal heart defect in ongenital heart disease（CHD）is associated with abnormal development of placenta and brain. One-stop-shop ‘heart-brain-placenta’ imaging is of great value in prenatal diagnosis of CHD fetuses. This review discusses the current research on the one-stop-shop ‘heart-brain-placenta’ imaging of CHD fetuses.

Placenta，fetal heart and brain affect each other in the process of fetal growth. They are influenced by genetic，environmental，epigenetic and hemodynamic factors，and share several key developmental pathways. Fetal heart defect in ongenital heart disease（CHD）is associated with abnormal development of placenta and brain. One-stop-shop ‘heart-brain-placenta’ imaging is of great value in prenatal diagnosis of CHD fetuses. This review discusses the current research on the one-stop-shop ‘heart-brain-placenta’ imaging of CHD fetuses.