OBJECTIVE To summarize the characteristics of treatment outcomes of the patients with biliary sepsis and analyze the risk factors for death.METHODS The patients with biliary sepsis who were treated in Hainan Hospital of Chinese PLA General Hospital from Jun.2019 to Oct.2024 were retrospectively recruited as the re-search subjects and were divided into the survival group and the death group according to 28-day treatment out-comes after the diagnosis of sepsis.The baseline data and the intervention measures during the hospital stay were compared between the two groups of patients,the indexes with statistical significance were set as independent var-iables,and the death was set as dependent variable.Multivariate logistic regression analysis was performed for the risk factors for the 28-day death of the patients with biliary sepsis.RESULTS A total of 103 patients with biliary sepsis were finally included in the study,with 34(33.01％)cases in the death group,69(66.99％)cases in the survival group.Univariate analysis showed that the proportions of patients with no less than 65 years of age,shock and biliary tract obstruction,the average acute physiology and chronic health evaluation scoring system(A-PACHEⅡ)score and average sequential organ failure assessment(SOFA)score were remarkably higher in the death group than in the survival group(P＜0.05).The result of multivariate logistic regression analysis indicated that the advanced age,shock,biliary tract obstruction,APACHE Ⅱ score and SOFA score were the independent risk factors for the short-term death of the patients with biliary sepsis.CONCLUSIONS The risk of 28-day death of the patients with biliary sepsis is associated with the advanced age,shock,biliary tract obstruction,APACHE Ⅱscore and SOFA score.The combination of the above factors has high value in prediction of death.

OBJECTIVE To summarize the characteristics of treatment outcomes of the patients with biliary sepsis and analyze the risk factors for death.METHODS The patients with biliary sepsis who were treated in Hainan Hospital of Chinese PLA General Hospital from Jun.2019 to Oct.2024 were retrospectively recruited as the re-search subjects and were divided into the survival group and the death group according to 28-day treatment out-comes after the diagnosis of sepsis.The baseline data and the intervention measures during the hospital stay were compared between the two groups of patients,the indexes with statistical significance were set as independent var-iables,and the death was set as dependent variable.Multivariate logistic regression analysis was performed for the risk factors for the 28-day death of the patients with biliary sepsis.RESULTS A total of 103 patients with biliary sepsis were finally included in the study,with 34(33.01％)cases in the death group,69(66.99％)cases in the survival group.Univariate analysis showed that the proportions of patients with no less than 65 years of age,shock and biliary tract obstruction,the average acute physiology and chronic health evaluation scoring system(A-PACHEⅡ)score and average sequential organ failure assessment(SOFA)score were remarkably higher in the death group than in the survival group(P＜0.05).The result of multivariate logistic regression analysis indicated that the advanced age,shock,biliary tract obstruction,APACHE Ⅱ score and SOFA score were the independent risk factors for the short-term death of the patients with biliary sepsis.CONCLUSIONS The risk of 28-day death of the patients with biliary sepsis is associated with the advanced age,shock,biliary tract obstruction,APACHE Ⅱscore and SOFA score.The combination of the above factors has high value in prediction of death.

Objective: To clarify the situation of the detection of upper gastrointestinal cancer and precancerous lesions in the Feicheng city and discuss the possible influencing factors. Methods: A cluster sampling method was used to determine the participants. A unified questionnaire was used to investigate the basic information including history of alcohol intake, smoking and chinese tea, as well as other eating habits, medical history of digestive tract and cancer. Endoscopy was used to to screen the patients with upper gastrointestinal cancer and precancerous lesions. Influential factors were explored by non-conditional logistic regression model. Results: 911 of 7 291participants were positive, and the total detection rate was 12.49%. The total positive detection rate of male and female was 17.94% and 8.71%, respectively (P<0.001). Multivariate logistic regression analysis showed that the sex (OR=0.527, 95%CI: 0.440-0.631), age (OR=2.037, 95%CI: 1.849-2.245), smoking (OR=1.240, 95%CI: 1.014-1.516) and alcohol consumption (OR=1.232, 95%CI: 1.012-1.500) , meat and protein intake (OR=0.794, 95%CI: 0.638-0.987) and drink tea (OR=1.233, 95%CI: 1.056-1.440) may be influencing factors of the total detection rate of upper gastrointestinal cancer and precancerosis. Conclusions In Feicheng city, intake of meat and protein is the protective factor of the upper gastrointestinal cancer and precancerous lesions. Men, aged, smoking, drinking and tea will increase the risk of upper gastrointestinal cancer and precancerous lesions.