1.Mechanism of platelet-rich plasma in promoting tissue regeneration and repair and its new exploration in endometrial regeneration and repair
Minghong SHEN ; Chengxiao LYU ; Hua DUAN
Chinese Journal of Reproduction and Contraception 2022;42(5):524-527
Platelet-rich plasma (PRP) is a concentrate of plasma rich in platelets, has become a hot spot in the field of tissue regeneration and repair. It releases a large number of bioactive factors, and may promote tissue regeneration and repair effectively. Intrauterine adhesion (IUA) is a disease caused by the damage of endometrial basal layer, which may lead to abnormal menstruation, infertility and recurrent miscarriages. It may seriously damage the reproductive and physiological functions in women of reproductive age. However, the existing treatment for IUA may not realize the regeneration and repair of endometrium successfully. Hence, several studies have explored the effects of PRP in endometrial regeneration and repair of IUA, and found that PRP could effectively promote the regeneration and repair of endometrium. Thus, the aim of this study is to review the mechanisms of PRP in accelerating tissue regeneration and repair, current application status, and research progress of PRP in endometrial regeneration of IUA.
2.Mechanism of platelet-rich plasma in promoting tissue regeneration and repair and its new exploration in endometrial regeneration and repair
Minghong SHEN ; Chengxiao LYU ; Hua DUAN
Chinese Journal of Reproduction and Contraception 2022;42(5):524-527
Platelet-rich plasma (PRP) is a concentrate of plasma rich in platelets, has become a hot spot in the field of tissue regeneration and repair. It releases a large number of bioactive factors, and may promote tissue regeneration and repair effectively. Intrauterine adhesion (IUA) is a disease caused by the damage of endometrial basal layer, which may lead to abnormal menstruation, infertility and recurrent miscarriages. It may seriously damage the reproductive and physiological functions in women of reproductive age. However, the existing treatment for IUA may not realize the regeneration and repair of endometrium successfully. Hence, several studies have explored the effects of PRP in endometrial regeneration and repair of IUA, and found that PRP could effectively promote the regeneration and repair of endometrium. Thus, the aim of this study is to review the mechanisms of PRP in accelerating tissue regeneration and repair, current application status, and research progress of PRP in endometrial regeneration of IUA.
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