Objective To observe ultrasonic manifestations of ovarian cysts in neonates and infants.Methods Totally 40 neonates or infants with large or complicated ovarian cysts were retrospectively enrolled,and ultrasonic manifestations,surgical operation findings or follow-up data were analyzed.Results Among 40 cases,thin wall and echoless unicellular cysts were found in 20 cases,among which 9 were accompanied by"ascus",and these cases were classified into simple cyst group.Thick wall cysts with spot-like,flocculent or heterogeneous solid components were observed in 19 cases,including 11 cases with"double wall sign",8 with solid-liquid stratification and 1 case with"ascus",and these cases were taken as complex cyst group.Atrophic solid cyst was found in 1 case.The long diameter,anteroposterior diameter and short diameter of simple cyst group were all larger than those of complex cyst group(all P＜0.05).Ultrasound correctly diagnosed ovarian origin tumors in 14 cases(14/40,35.00％).Hemorrhage combined with torsion necrosis was detected in 18 cases of complicated ovarian cysts in surgical operation.Thirty-eight cases were confirmed by surgical pathology,while 2 cases were confirmed by follow-up,including 1 case of simple ovarian cyst spontaneously subsided and 1 case of complicated ovarian cyst fell off and migrated to right lower liver margin.Conclusion Ovarian cysts in neonates and infants could be roughly divided into simple and complex and atrophic solid ovarian cysts,with ultrasonic manifestations having certain characteristics,which were helpful for diagnosis.

Background::Clinical opportunistic screening is a cost-effective cancer screening modality. This study aimed to establish an easy-to-use diagnostic model serving as a risk stratification tool for identification of individuals with malignant gastric lesions for opportunistic screening.Methods::We developed a questionnaire-based diagnostic model using a joint dataset including two clinical cohorts from northern and southern China. The cohorts consisted of 17,360 outpatients who had undergone upper gastrointestinal endoscopic examination in endoscopic clinics. The final model was derived based on unconditional logistic regression, and predictors were selected according to the Akaike information criterion. External validation was carried out with 32,614 participants from a community-based randomized controlled trial.Results::This questionnaire-based diagnostic model for malignant gastric lesions had eight predictors, including advanced age, male gender, family history of gastric cancer, low body mass index, unexplained weight loss, consumption of leftover food, consumption of preserved food, and epigastric pain. This model showed high discriminative power in the development set with an area under the receiver operating characteristic curve (AUC) of 0.791 (95% confidence interval [CI]: 0.750–0.831). External validation of the model in the general population generated an AUC of 0.696 (95% CI: 0.570–0.822). This model showed an ideal ability for enriching prevalent malignant gastric lesions when applied to various scenarios.Conclusion::This easy-to-use questionnaire-based model for diagnosis of prevalent malignant gastric lesions may serve as an effective prescreening tool in clinical opportunistic screening for gastric cancer.

Objective To observe ultrasonic manifestations of ovarian cysts in neonates and infants.Methods Totally 40 neonates or infants with large or complicated ovarian cysts were retrospectively enrolled,and ultrasonic manifestations,surgical operation findings or follow-up data were analyzed.Results Among 40 cases,thin wall and echoless unicellular cysts were found in 20 cases,among which 9 were accompanied by"ascus",and these cases were classified into simple cyst group.Thick wall cysts with spot-like,flocculent or heterogeneous solid components were observed in 19 cases,including 11 cases with"double wall sign",8 with solid-liquid stratification and 1 case with"ascus",and these cases were taken as complex cyst group.Atrophic solid cyst was found in 1 case.The long diameter,anteroposterior diameter and short diameter of simple cyst group were all larger than those of complex cyst group(all P＜0.05).Ultrasound correctly diagnosed ovarian origin tumors in 14 cases(14/40,35.00％).Hemorrhage combined with torsion necrosis was detected in 18 cases of complicated ovarian cysts in surgical operation.Thirty-eight cases were confirmed by surgical pathology,while 2 cases were confirmed by follow-up,including 1 case of simple ovarian cyst spontaneously subsided and 1 case of complicated ovarian cyst fell off and migrated to right lower liver margin.Conclusion Ovarian cysts in neonates and infants could be roughly divided into simple and complex and atrophic solid ovarian cysts,with ultrasonic manifestations having certain characteristics,which were helpful for diagnosis.

Objective:To investigate the effect of optimized catheter clipping training and automatic balloon retraction ureteral catheter removal on first urination of patients after neurosurgery, and provide guidance for postoperative micturition of these patients.Methods:From August 2020 to August 2021, 208 patients admitted to Department of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, undergoing craniocerebral surgery under general anesthesia and indurating catheter were selected as the study subjects by convenient sampling. They were divided into control group ( n=69), observation group A ( n=69) and observation group B( n=70) by random number table method. The control group received routine catheter clipping training and routine ureteral catheter removal, the observation group A received optimized catheter clipping training and routine ureteral catheter removal, and the observation group B received optimized catheter clipping training and automatic balloon retraction ureteral catheter removal. The first micturition time, first micturition volume, micturition circumstance, pain score and urethral irritation sign of the three groups were observed and compared. Results:The first urination time in observation group A and B were (11.58 ± 6.59) min and (10.06 ± 5.91) min, respectively, lower than (37.14 ± 13.74) min in control group, and the difference was statistically significant ( t=13.94, 15.07, both P<0.05); there was no significant difference between observation group B and observation group A ( P>0.05). The first urine volume were (303.66 ± 43.74) ml in control group, (299.06 ± 41.26) ml in observation group A and (299.28 ± 43.17) ml in observation group B, and the difference was not statistically significant ( P>0.05). The incidence of urination (spontaneous urination, induced urination and urinary retention) in observation group A was better than control group ( χ2=16.47), while observation group B was better than observation group A and control group ( χ2=8.59, 37.83), the differences were statistically significant (all P<0.05). There was no significant difference in pain score of ureteral catheter removal between observation group A (2.71 ± 0.67) and control group (2.87 ± 0.78) ( P>0.05). The score of observation group B (1.41 ± 0.65) was lower than that of control group and observation group A, the differences were statistically significant ( t=11.93, 11.62, both P<0.05). There was no significant difference of the incidence of urethral irritation (grade 0, 1, 2, and 3) between observation group A and control group ( P>0.05). Observation group B was lower than control group and observation group A, the differences were statistically significant ( t=38.81, 25.27, both P<0.05). Conclusions:Optimized catheter clipping training and automatic balloon retraction ureteral catheter removal can effectively shorten the first urination time of patients after neurosurgery, reduce the pain of ureteral catheter removal and urethral irritation during the first urination, improve the success rate of the first urination, and effectively prevent the occurrence of urinary retention.

Objective:An automatic analysis system for radiotherapy planning was developed to realize the automatic analysis of dose parameters of radiotherapy planning through the intelligent analysis of the underlying data of Pinnacle 3 treatment planning system (TPS). Methods:The radiotherapy plans of 12 patients with esophagus cancer were analyzed. The automatic analysis system automatically retrieved the Pinnacle 3 TPS database, obtained the raw data of 12 cases of treatment plan, and automatically analyzed the underlying raw data, reconstructed contours, radiation fields, and dose parameters, and recalculated dose distribution and dose-volume histograms. The accuracy of the recalculation of the volume and dose data of the new system was evaluated by comparing with volume and dose data from the original plans of online TPS. Results:The automatic analysis system successfully parsed the underlying data of the treatment plan and reconstructed the parameters of the treatment plan. The volume deviation between the contour calculated by the new system and the original plans was ≤0.1%; Compared with the reference dose of the original plans, the deviations of dose parameters (D max, D mean, D 95, and D 50 for GTV, PGTV, CTV, and PTV) recalculated by the new analysis system were ≤1.0%; The deviations of D max and D mean of recalculated ROIs from the original plans were <5%. Conclusions:The automatic analysis system can directly analyze the underlying data of the Pinnacle 3 TPS treatment plan, reconstruct the treatment plan, calculate the contour volume and dose parameters, and the dose deviations from the original plans meet clinical requirements

ObjectiveTo observe the dose of methadone and the compliance of patients to the methadone maintenance treatment(MMT).MethodsWe analyzed the status of 69 patients who were addicted to opiate medication and 44 patients who dropped out in our clinic until July 31,2010.ResultsThere was no significant relationship between patients' urine test and the dose.Crime caused the patients who dropped out.The percentage of positive urine did not decline as the dose increased,but the rate of patients who dropped and the number of positive urine test showed a significant correlation( r =0.523 P =0.000).Crime was the main reason that affected the compliance to MMT and caused dropping out.ConclusionThe use of MMT dose should be individualized.

As an important human body sound signal, heart sound is of great value in the researches on diagnostics of heart diseases. This study sought to explore the methods of transmitting heart sound through the telephone correspondence system for simultaneous telemetering cardiac contractility and heart rate. Heart sounds were transmitted from a phone to another phone with 4 modes, the wirelessly transmitted distance between the two phones being 5 m, 10 km, and 1000 km, respectively. The results of experiments show that telemetering cardiac contractility and heart rate can be realized by the telephone correspondence system. Such methods have the advantages of being noninvasive, inexpensive, rapid and convenient; moreover, they can be used repeatedly and be available for in-home use.
Heart Sounds ; physiology ; Humans ; Phonocardiography ; instrumentation ; methods ; Signal Processing, Computer-Assisted ; instrumentation ; Telemedicine ; methods ; Telemetry ; methods