1.Comparison of the therapeutic effects of antimicrobial photodynamic therapy combined with subgingival scaling and root planing in the treatment of chronic periodontitis
Pengfei YANG ; Chengli XIONG ; Chengrong LIU
Chongqing Medicine 2025;54(10):2366-2370
Objective To evaluate the therapeutic effect of antimicrobial photodynamic therapy(aPDT)combined with subgingival scaling and root planing(SRP)on chronic periodontitis.Methods A total of 198 patients with chronic periodontitis who were diagnosed and treated in the Department of Stomatology of the hospital from August 2023 to April 2024 were selected as the study subjects.A randomized block design was used to divide the patients into a control group(n=98)and an experimental group(n=98).The control group received oral education and SRP treatment,while the experimental group received oral education and aPDT+SRP treatment.The depth of periodontal pocket probing(PD),positive rate of bleeding probing(BOP),bleeding index(BI),and plaque index(PLI)were compared of patients before and after 6 weeks of treatment,and the levels of tumor necrosis factor-α(TNF-α)and IL-6 in gingival crevicular fluid were meas-ured.Results After treatment,the proportion of patients with PLI grade 0 and 1 in the experimental group was higher than the control group(x2=30.640,P<0.001).The PD of the experimental group was lower than that of the control group(t=9.420,P<0.001).The AL of the experimental group was lower than that of the control group(t=4.495,P<0.001).The proportion of patients with grade 0 and grade 1 of BI index in the experimental group was higher(x2=48.839,P<0.001).The average levels of IL-6 and TNF-α in the ex-perimental group were lower than those in the control group(P<0.001).Conclusion SRP+aPDT therapy not only effectively improves periodontal clinical indicators in patients with chronic periodontitis,but also sig-nificantly reduces the levels of local inflammatory factors,which is worthy of promotion and application.
2.Surgical treatment and perioperative multidisciplinary management of neuromuscular scoliosis in children
Longtao QI ; Yao ZHAO ; Beiyu XU ; Chunde LI ; Hui XIONG ; Chengli QUE ; Zhen HUANG ; Xiao HU
Chinese Pediatric Emergency Medicine 2023;30(6):427-433
Scoliosis is a common deformity in neuromuscular disease, which usually has the characteristics of early onset age, severe degree of deformity, and rapid progression.Neuromuscular scoliosis often leads to serious damages to the quality of life, and results in the loss of walking, standing and sitting, and cardiopulmonary insufficiency.Surgical treatment can improve the quality of life for children with neuromuscular scoliosis, but surgical treatment is still challenging due to the complex surgery and many complicated diseases.The complications are much higher than those of idiopathic scoliosis.A multidisciplinary team is necessary in the surgical treatment of neuromuscular scoliosis to promptly and effectively reduce the complications.

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