1.Perspectives of Femoroacetabular Impingement Syndrome: A Bibliometric Analysis
Alexander David PUYOL ; Charlotte GANDERTON ; Matthew KING ; Oren TIROSH
Hip & Pelvis 2026;38(2):117-126
Femoroacetabular impingement syndrome (FAIS) is a risk factor for future hip osteoarthritis and is prevalent in both athletic and non-athletic populations. This bibliometric review aimed to understand the history of FAIS and provide detailed information for future FAIS research. The Clarivate Analytics Web of Science Core Collection was used to search and obtain all studies between 2020 and 2025 using bibliometrix (ver. 3.0.4) and R package software. Between 2020 and 2025, 1,486 articles were published on FAIS. There was an overall 41.3% downward trend in published research during this period. Furthermore, recent key terms include “physical impairments” and “muscle strength”. Institutions and surgical authors across North America, Europe, and Australia published the highest volume of research papers. Across keywords, femoroacetabular impingement and osteoarthritis had the strongest relationship. FAIS research continues to be led by surgical authors within surgical journals. While surgical key terms have been historically prevalent within the existing literature, research aligning with more conservative management has started to emerge. Despite an increase in physiotherapy researchers, inter-disciplinary collaboration remains limited and concentrated in western countries.
3.Molecular characterization of the feline T-cell receptor gamma alternate reading frame protein (TARP) ortholog.
Alexander Th A WEISS ; Marie Charlotte VON DEETZEN ; Werner HECHT ; Manfred REINACHER ; Achim D GRUBER
Journal of Veterinary Science 2012;13(4):345-353
T-cell receptor gamma alternate reading frame protein (TARP) is expressed by human prostate epithelial, prostate cancer, and mammary cancer cells, but is not found in normal mammary tissue. To date, this protein has only been described in humans. Additionally, no animal model has been established to investigate the potential merits of TARP as tumor marker or a target for adoptive tumor immunotherapy. In this study conducted to characterize feline T-cell receptor gamma sequences, constructs very similar to human TARP transcripts were obtained by RACE from the spleen and prostate gland of cats. Transcription of TARP in normal, hyperplastic, and neoplastic feline mammary tissues was evaluated by conventional RT-PCR. In felines similarly to the situation reported in humans, a C-region encoding two open reading frames is spliced to a J-region gene. In contrast to humans, the feline J-region gene was found to be a pseudogene containing a deletion within its recombination signal sequence. Our findings demonstrated that the feline TARP ortholog is transcribed in the prostate gland and mammary tumors but not normal mammary tissues as is the case with human TARP.
Animals
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Cats
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Continental Population Groups
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Humans
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Immunotherapy
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Models, Animal
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Open Reading Frames
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Prostate
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Prostatic Neoplasms
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Protein Sorting Signals
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Pseudogenes
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Reading Frames
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Receptors, Antigen, T-Cell
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Recombination, Genetic
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Spleen

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