AIM: To investigate how angles kappa and alpha affect postoperative visual quality in patients with multifocal intraocular lens(mIOLs)implantation.METHODS: Retrospective cases series. A total of 46 patients(46 eyes)who underwent phacoemulsification were subsumed. The correlation between Preoperative angles kappa and alpha, wave-front aberrations and objective visual quality of cornea, internal, and total eye after surgery were analyzed using iTrace.RESULTS: The magnitude of angle kappa was negatively correlated with internal and total modulation transfer function(MTF)at 3 mm; the magnitude of angle kappa was positively correlated with astigmatism, trefoil, higher-order aberrations(HOAs)of both internal and total eye at 3 mm. The magnitude of angle alpha was negatively correlated with total MTF and total Strehl ratio at 3 mm. The magnitude of angle alpha was positively correlated with corneal coma at 5 mm, internal astigmatism at both 3 mm and 5 mm, and total spherical aberration(SA)at 3 mm. Multivariate linear regression analysis showed that, among candidate independent variables(kappa, alpha, astigmatism, SA, coma, trefoil, and HOAs), astigmatism is the only independent factor for altering corneal MTF at 3 mm and 5 mm; astigmatism and HOAs emerged as independent factors for altering internal MTF at 3 mm and 5 mm, and total MTF at 3 mm; astigmatism, SA and HOAs emerged as independent factors for altering total MTF at 5 mm.CONCLUSION: With greater preoperative angle kappa or angle alpha, patients who accept mIOL implantation tend to have larger internal astigmatism and HOAs, which resulting in poor visual quality, especially those with small pupil size.

Objective To explore the impact and prevention strategies of medical device adverse events in a children's hospital,and to improve the monitoring and management capabilities of medical device adverse events.Methods We retrieved 367 medical device adverse events that occurred in a children's hospital from 2017 to 2022.Using Excel software,we analyzed,organized,and statistically summarized the annual reports of adverse events,the distribution of event grades,the age distribution of involved patients,and the main medical devices involved.Results The annual reports of medical device adverse events showed an overall upward trend.Grade Ⅲ and Ⅳ adverse events accounted for the majority,representing 97.28％of the total re-ports.The main age group affected was 0-3 years old,accounting for 43.60％of the total adverse event reports.Disposable ster-ile syringes,disposable vacuum blood collection tubes,disposable gastric tubes,disposable infusion sets(with needles),dispos-able intravenous catheters,and other polymer products accounted for a high proportion of adverse events.Adverse events related to infusion,nursing,and protective equipment also accounted for a high proportion.Conclusion Adopting measures such as continuous monitoring and analysis of medical device adverse event reports,improving the construction of adverse event systems,strengthening professional skill training for medical staff,and enhancing quality management are conducive to improving the man-agement level of medical device adverse events in hospitals and ensuring patient safety.

Objective To explore the impact and prevention strategies of medical device adverse events in a children's hospital,and to improve the monitoring and management capabilities of medical device adverse events.Methods We retrieved 367 medical device adverse events that occurred in a children's hospital from 2017 to 2022.Using Excel software,we analyzed,organized,and statistically summarized the annual reports of adverse events,the distribution of event grades,the age distribution of involved patients,and the main medical devices involved.Results The annual reports of medical device adverse events showed an overall upward trend.Grade Ⅲ and Ⅳ adverse events accounted for the majority,representing 97.28％of the total re-ports.The main age group affected was 0-3 years old,accounting for 43.60％of the total adverse event reports.Disposable ster-ile syringes,disposable vacuum blood collection tubes,disposable gastric tubes,disposable infusion sets(with needles),dispos-able intravenous catheters,and other polymer products accounted for a high proportion of adverse events.Adverse events related to infusion,nursing,and protective equipment also accounted for a high proportion.Conclusion Adopting measures such as continuous monitoring and analysis of medical device adverse event reports,improving the construction of adverse event systems,strengthening professional skill training for medical staff,and enhancing quality management are conducive to improving the man-agement level of medical device adverse events in hospitals and ensuring patient safety.

Major depressive disorder (MDD) is one of the most disabling illnesses, and approximately one-third of patients with MDD fail to show significant improvement after multiple courses of antidepressants, eventually progressing to treatment-resistant depression (TRD), a more severe and complex subtype that is difficult to treat. Obsessive-compulsive disorder (OCD) is a type of mental disorder characterized by repetitive obsessions and/or compulsive behaviors, and the high rate of comorbidity with other psychiatric disorders has been identified as a hallmark feature of OCD. In particular, OCD frequently co-occurs with MDD, and when these two conditions overlap, the resulting comorbidity is characterized by more severe symptoms and an increased risk of suicide. Magnetic seizure therapy (MST) is a novel, non-invasive neuromodulation technique that is safe and effective in the treatment of TRD with less cognitive impairment. This paper describes a case of significant symptom improvement following 100 Hz accelerated MST treatment in a patient with comorbid TRD and OCD. As a novel treatment option, MST requires further large-scale clinical trials to explore in the future.

Major depressive disorder (MDD) is one of the most disabling illnesses, and approximately one-third of patients with MDD fail to show significant improvement after multiple courses of antidepressants, eventually progressing to treatment-resistant depression (TRD), a more severe and complex subtype that is difficult to treat. Obsessive-compulsive disorder (OCD) is a type of mental disorder characterized by repetitive obsessions and/or compulsive behaviors, and the high rate of comorbidity with other psychiatric disorders has been identified as a hallmark feature of OCD. In particular, OCD frequently co-occurs with MDD, and when these two conditions overlap, the resulting comorbidity is characterized by more severe symptoms and an increased risk of suicide. Magnetic seizure therapy (MST) is a novel, non-invasive neuromodulation technique that is safe and effective in the treatment of TRD with less cognitive impairment. This paper describes a case of significant symptom improvement following 100 Hz accelerated MST treatment in a patient with comorbid TRD and OCD. As a novel treatment option, MST requires further large-scale clinical trials to explore in the future.