Cytidine/uridine monophosphate kinase 2(CMPK2)is an interferon-stimulated gene that plays an important role against viral infections.CMPK2 is also a rate-limiting enzyme in mitochon-dria that maintains intracellular levels of UTP/CTP and can affect inflammation triggered by path-ogenic infections and other causes of alterations in mitochondria.In this article,we review the structure and distribution of CMPK2,its role in responding to pathogenic infections and the regu-lation of inflammation,and the associated signaling pathways.

Cytidine/uridine monophosphate kinase 2(CMPK2)is an interferon-stimulated gene that plays an important role against viral infections.CMPK2 is also a rate-limiting enzyme in mitochon-dria that maintains intracellular levels of UTP/CTP and can affect inflammation triggered by path-ogenic infections and other causes of alterations in mitochondria.In this article,we review the structure and distribution of CMPK2,its role in responding to pathogenic infections and the regu-lation of inflammation,and the associated signaling pathways.

Objective To explore the impact of pregnancy knowledge training on contraception and further unplanned pregnancies in outpatient induced abortion patients. Methods Select 114 case of abortion patients in our hospital during March 2015～November 2016, randomly divide them to intervention group (pregnancy knowledge training, 57 cases) and routine group (routine follow-up, 57 cases). Two groups of patients were followed up for 1 year after intervention, compared the mastery of contraceptive knowledge, the incidence of unwanted pregnancies again and satisfaction. Results The intervention group patients health knowledge to master the excellent and good rate was significantly higher than the conventional group (87. 72％ vs. 56. 14％, P＜0. 05). The rate of unexpected pregnancy again was significantly lower in the dry group than in the conventional group (3. 51％ vs. 19. 30％, P＜0. 05). The intervention group patients satisfaction was significantly higher than the conventional group. Conclusion Pregnancy knowledge training in outpatient abortion patients can effectively improve the control of patients with contraceptive knowledge and reduce the incidence of postoperative unwanted pregnancies and improve patient satisfaction.