1.Applications and prospects of 5G+helicopter medical rescue
Wei HAN ; Danni HUANG ; Junchao WANG ; Yuanting LI ; Changgen CHEN ; Xiang LI ; Zhongliang JI ; Qin LI ; Zhuang LI
Chinese Journal of Aerospace Medicine 2025;36(1):72-78
Objective:To review the applications of key technologies of 5G+helicopter medical rescue and predict future developments. Literature resource and selection Related literature in this field that was published at home and abroad. Literature quotation Forty articles published at home and abroad. Literature synthesis 5G+helicopter medical rescue is a new medical rescue model that integrates airborne 5G network technology, body area network disease awareness technology and 5G air-ground collaborative rapid diagnosis and treatment technology. It can shorten the time and space distance of medical rescue and improve the efficiency. The clinical applications of 5G+helicopter medical rescue, including the development of rescue schemes, daily and disaster scenarios 5G networking schemes, and air-ground collaborative emergency rescue information sharing platforms, have delivered remarkable results in the field of medical rescue. Despite the challenges facing 5G technology such as high cost and inconsistent technical standards, its development will promote innovation and progress in low-airspace helicopter medical rescue and offer more efficient, more accurate and safer rescue services. Conclusions:It is recommended that 5G network be given more weight, the auto-flight technology of helicopters developed, rescue command and dispatch platforms established, rescue personnel better-trained and supervision and safety guarantee be enhanced.
2.Applications and prospects of 5G+helicopter medical rescue
Wei HAN ; Danni HUANG ; Junchao WANG ; Yuanting LI ; Changgen CHEN ; Xiang LI ; Zhongliang JI ; Qin LI ; Zhuang LI
Chinese Journal of Aerospace Medicine 2025;36(1):72-78
Objective:To review the applications of key technologies of 5G+helicopter medical rescue and predict future developments. Literature resource and selection Related literature in this field that was published at home and abroad. Literature quotation Forty articles published at home and abroad. Literature synthesis 5G+helicopter medical rescue is a new medical rescue model that integrates airborne 5G network technology, body area network disease awareness technology and 5G air-ground collaborative rapid diagnosis and treatment technology. It can shorten the time and space distance of medical rescue and improve the efficiency. The clinical applications of 5G+helicopter medical rescue, including the development of rescue schemes, daily and disaster scenarios 5G networking schemes, and air-ground collaborative emergency rescue information sharing platforms, have delivered remarkable results in the field of medical rescue. Despite the challenges facing 5G technology such as high cost and inconsistent technical standards, its development will promote innovation and progress in low-airspace helicopter medical rescue and offer more efficient, more accurate and safer rescue services. Conclusions:It is recommended that 5G network be given more weight, the auto-flight technology of helicopters developed, rescue command and dispatch platforms established, rescue personnel better-trained and supervision and safety guarantee be enhanced.
3.Key Techniques of Three-Dimensional Electrophysiology Catheter Positioning Based on Magnetic-Electric Fusion
Yu CHEN ; Zehui SUN ; Xianliang HE ; Changgen CHEN ; Bingbing XUE ; Libin MENG ; Ye LI
Chinese Journal of Medical Instrumentation 2024;48(6):631-638
In cardiac ablation procedures,the accuracy of catheter positioning determines the authenticity of the cardiac model and the accuracy of the ablation target.This article reviews the literature on catheter positioning in electrophysiology and summarizes the key technologies for catheter positioning,such as magnetic-electric fusion and interference suppression.Addressing the limitations of electric and magnetic positioning individually,the paper elaborates on the rationale for catheter positioning technology based on magnetic-electric fusion.It also outlines the framework of a complex catheter positioning system.Specifically,the magnetoelectric conversion matrix is established first,followed by the optimization of the catheter shape.The interference factors such as magnetic field interference,body movement,respiration,and heartbeat in catheter positioning and their suppression methods are analyzed and discussed in detail.Finally,the development trend of three-dimensional electrophysiology catheter positioning technology is prospected,offering feasible insights for the research on catheter positioning technology based on magnetic-electric fusion.
4.Platelets promote the enhanced tumor metastasis of bone marrow mesenchymal stem cells
Zhuqian LI ; Qianqian WANG ; Changgen XU ; Hongge JI ; Yilong LU ; Xiangdong ZHAO ; Rong QIU ; Li SUN ; Bin CHEN ; Mei WANG ; Wenrong XU ; Wei ZHU
Chinese Journal of Clinical Laboratory Science 2018;36(2):148-151
Objective To investigate the effect of human bone marrow mesenchymal stem cells (BM-MSCs) stimulated by platelets in vitro on the metastasis of cancer cells.Methods The BM-MSCs were isolated and cultured in vitro and platelets from the peripheral blood of healthy persons were purified.The MSCs (control),platelets + MSCs,and platelets treated with culture media (CM) of SGC-7901 tumor cells + MSCs (T-platelets + MSCs) were cultured,respectively,and the MSCs and supernatants (MSCs-CM and SGC-7901-CM) were collected,respectively,after 24 hours.The expressions of markers of cancer-associated fibroblasts (CAF),such as α-SMA and Vimentin,were determined by Western-blotting.The immigration ability of BM-MSCs were analyzed by Transwell assay.The levels of P-selectin in platelets stimulated by MSCs-CM or SGC-7901-CM were detected with flow cytometry.The metastasis model of gastric cancer SGC-7901 cells was established in BALB/c nude mice by the injection of tail vein,and the tumor metastasis in vivo was observed.Results The expression levels of P-selectin in platelets stimulated by MSCs-CM ([21.37 ± 1.00] %) or SGC-7901-CM ([31.4 ± 1.71] % were significantly higher than that in the control ([3.17 ± 0.40] %,t =27.85 and 29.18,P < 0.01).The expression levels of α-SMA and Vimentin in platelets + MSCs group (0.79 ± 0.08 and 0.88 ± 0.01) and T-platelets + MSCs group (0.90 ±0.06 and 0.96 ±0.04) were significantly higher than that in the control (0.64 ±0.02 and 0.75 ±0.05,t =2.96 and 6.45 forα-SMA,t =4.73 and 5.73 for Vimentin,P <0.01).The amounts of immigration cells in platelets + MSCs group (340.3 ±27.7) and T-platelets ± MSCs group (424.3 ± 17.6) were significantly higher than that in the control (220.7 ± 19.4,t =6.14 and 13.48,P < 0.01).The in vivo experimental results showed that the metastatic foci in platelets ± MSCs group (4 ± 2) and T-platelets ± MSCs group (21 ± 4) were significantly higher than that in the control (0.33 ± 0.06,t =3.051 and 8.857,P < 0.01).Conclusion Platelets promote the immigration and the enhanced tumor metastasis in vivo of BM-MSCs.
5.Relationship between hemorrheologic alteration and the femoral head necrosis after long-term glucocorticoid treatment
Changgen HU ; Junchang CHEN ; Xijing HE ; Kunzheng WANG ; Qiang LIU
Journal of Xi'an Jiaotong University(Medical Sciences) 2003;0(06):-
Objective To explore the relationship between blood flow viscosity and femoral head necrosis after long-term glucocorticoid treatment (FHNG). Methods Blood and plasma viscosity, blood flow speed, RBC fragility, electrophoresis time, and the speed of blood flow were measured. Cellular ultrastructural changes of FHNG were studied with electron microscope. Results Blood viscosity of the treatment group increased obviously at the 8th week compared with that of control group (P
6.Mechanism of femoral head necrosis induced by long term glucocorticoid treatment in rabbit model
Changgen HU ; Junchang CHEN ; Qiang LIU
Chinese Journal of Orthopaedics 2001;0(06):-
Objective To explore the mechanism of the femoral head necrosis induced with long term glucocorticoid treatment by means of microvascular density and cellular ultrastructure. Methods 40 Japanese rabbits were used to establish an animal model of the femoral head necrosis induced by long term glucocorticoid treatment using injection with methylprednisolone 8 mg/kg weekly. In studying cellular ultrastructure and microvascular density of the femoral head necrosis models, the slides were made after vascular infusion with Chinese ink on 4th, 8th, and 12th week of the experiment. The network of microvasculature of the rabbit ear was photographied as a reference data before and after methylprednisolone treatment. Results Microvascular density in bilateral cancellous and compact bone of the femoral head became decreased statistically after 12 weeks of glucocorticoid treatment(P

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