The long-term prognosis of complex regional pain syndrome is difficult to predict because of its unclear pathophysiology. The syndrome can spontaneously spread to other regions in the body. We report a case in which a complex regional pain syndrome that occurred in a 75-year-old male patient after a stroke spread to the opposite side.
Aged ; Causalgia ; Humans ; Male ; Prognosis ; Reflex Sympathetic Dystrophy ; Stroke

Complex regional pain syndrome (CRPS) type II is a syndrome that develops after nerve injury. Symptoms may be severe, and vary depending on the degree of sympathetic nerve involvement. As yet, there is no satisfactory treatment. We report the case of a female patient who had an L5 left transverse process fracture and an S2 body fracture, who developed symptoms of CRPS type II in her left lower leg that were aggravated during ambulation in spite of absolute bed rest for one month after the trauma. Several treatments, including bed rest, medication, and numerous nerve blocks were attempted, but the pain persisted. We finally tried injection of polydeoxyribonucleotide (PDRN) solution at the left L5 transverse process fracture site because we knew of the anti-inflammatory effect of PDRN. One day after this treatment, her symptoms had almost disappeared and three days later, she was discharged. We will also further discuss the possibility of using PDRN solution for the treatment of CRPS.
Bed Rest ; Causalgia* ; Female ; Humans ; Leg ; Nerve Block ; Polydeoxyribonucleotides ; Walking

The superficial peroneal nerve is vulnerable to damage from ankle sprain injuries and fractures as well as surgery to this region. And it is also one of the most commonly involved nerves in complex regional pain syndrome type II in the foot and ankle region. We report two cases of ultrasound-guided pulsed radiofrequency treatment of superficial peroneal nerve for reduction of allodynia in CRPS patients.
Ankle ; Ankle Injuries ; Causalgia ; Foot ; Humans ; Hyperalgesia* ; Neuralgia ; Peripheral Nerves ; Peroneal Nerve* ; Pulsed Radiofrequency Treatment* ; Ultrasonography

PURPOSE: The purpose of this study was to report the clinical outcome of "modified Bouquet technique", as a simple and effective internal fixation with Kirschner-wire for the metacarpal neck fractures. METHODS: Sixty-seven patients with metacarpal neck fracture treated by modified Bouquet technique were retrospectively reviewed. The operation time and removal time were evaluated. For radiologic evaluation, posterior angulation of fracture and metacarpal shortening were measured pre and postoperatively. For clinical evaluation, range of motion of metacarpophalangeal joint, Green and O'Brien score were evaluated. RESULTS: Preoperative neck shaft angle of metacarpal bone was 46.0° and length of metacarpal bone was 51.2 mm, and postoperative neck shaft angle was 24.4° (p=0.003) and length of metacarpal length was 52.8 mm (p=0.031) in average. The mean range of motion was 86.6° and Green and O'Brien score was 96.1 points at last visit. We had one complicated case with type II complex regional pain syndrome of affected hand with hypertrophic scar formation. CONCLUSION: Modified Bouquet technique for metacarpal neck fracture is a good method using just two K-wires, plier and mallet without electric devices in short operation time. The technique can correct angulation of fracture site, rotation of finger and metacarpal shortening by controlling inserted K-wires with high bone union rate with less joint stiffness.
Causalgia ; Cicatrix, Hypertrophic ; Fingers ; Hand ; Humans ; Joints ; Metacarpophalangeal Joint ; Methods ; Neck* ; Range of Motion, Articular ; Retrospective Studies

Complex regional pain syndrome (CRPS) is often a devastating neuropathic condition that has been recognized with increasing frequency in the lower extremities. Patients with CRPS may worsen to such a degree that the individual may never return to a satisfactory and productive life. Spinal cord stimulation (SCS) is one of the most minimally invasive and effective treatments for intractable pain such as CRPS. The most important factor for successful stimulation of the spinal cord is proper lead position that stimulation and pain regions match completely. A 39-year-old male patient, suffering from CRPS type II in his lower extremity, visited our pain clinic. It was a difficult case that the electrode for spinal cord stimulation was positioned at the proper site due to the adhesion of the epidural space by frequent epidural blocks and procedures. We report the efficacy of a steerable epidural catheter for adhesiolysis on the setting the electrode to the proper site in the epidural space.
Adult ; Catheters ; Causalgia ; Electrodes ; Epidural Space ; Humans ; Lower Extremity ; Male ; Pain Clinics ; Pain, Intractable ; Spinal Cord ; Spinal Cord Stimulation ; Stress, Psychological

BACKGROUND: An independent medical examination (IME) is a critical process for awarding reparation for injury. However, conducting an IME in pain medicine is very difficult, not only because pain is a subjective symptom, but also because there are no proper objective methods to demonstrate it. This study was conducted to compare IME reports and the court decisions on the disability status of the patients. METHODS: We analyzed 79 IME reports and 25 corresponding court decisions on the disability status of patients. The diagnoses, causal relationships between the patients' status and the trauma, McBride's degree of disability, the American Medical Association's impairment ratings, the estimated annual cost for future treatment, and the necessity of care-giving were compared and analyzed. RESULTS: The diagnoses in the 79 cases were complex regional pain syndrome (CRPS) type I (58 cases), CRPS type II (7 cases), peripheral neuropathy (5 cases), myofascial pain syndrome (4 cases), herniated intervertebral disc (2 cases), and fibromyalgia (1 case). The types of accidents were road traffic accidents (50 cases), military injuries (14 cases), industrial accidents (11 cases), and others (4 cases). The IME reports and the court decisions stated considerably different McBride's degrees of disability (P = 0.014). However, there was no significant difference in the estimated cost for future treatment between the IME reports and the court decisions (P = 0.912). CONCLUSION: IME reports should be accurate, fair, and based on objective findings. Feedback on IMEs from the court decisions is helpful for reference use.
Accidents, Occupational ; Accidents, Traffic ; Awards and Prizes ; Causalgia ; Disability Evaluation ; Fibromyalgia ; Humans ; Intervertebral Disc ; Jurisprudence ; Military Personnel ; Myofascial Pain Syndromes ; Peripheral Nervous System Diseases

A 54-year-old man experienced injury to the second finger of his left hand due to damage from a paintball gun shot 8 years prior, and the metacarpo-phalangeal joint was amputated. He gradually developed mechanical allodynia and burning pain, and there were trophic changes of the thenar muscle and he reported coldness on his left hand and forearm. A neuroma was found on the left second common digital nerve and was removed, but his symptoms continued despite various conservative treatments including a morphine infusion pump on his left arm. We therefore attempted median nerve stimulation to treat the chronic pain. The procedure was performed in two stages. The first procedure involved exposure of the median nerve on the mid-humerus level and placing of the electrode. The trial stimulation lasted for 7 days and the patient's symptoms improved. The second procedure involved implantation of a pulse generator on the left subclavian area. The mechanical allodynia and pain relief score, based on the visual analogue scale, decreased from 9 before surgery to 4 after surgery. The patient's activity improved markedly, but trophic changes and vasomotor symptom recovered only moderately. In conclusion, median nerve stimulation can improve chronic pain from complex regional pain syndrome type II.
Arm ; Burns ; Causalgia ; Chronic Pain ; Cold Temperature ; Electrodes ; Fingers ; Forearm ; Hand ; Humans ; Hyperalgesia ; Infusion Pumps ; Joints ; Median Nerve ; Middle Aged ; Morphine ; Muscles ; Neuroma

BACKGROUNDDeafferentation pain is a kind of chronic pain syndrome and hard to manipulate. To evaluate the effectiveness and safety of junctional dorsal root entry zone (DREZ) coagulation, 23 consecutive patients with intractable deafferentation pain syndrome were studied.

METHODSTwenty-three patients underwent junctional DREZ coagulation (C5-T1 for upper extremities and L2-S1 for lower extremities) under general anesthesia. The pain severity was evaluated by the short McGill pain questionnaire (MPQ) and the visual analog scale (VAS), and the depression and anxiety of patients were assessed by Hamilton rating scale for depression (HRSD), Hamilton anxiety scale (HAMA), self-rating anxiety scale (SAS) and self-rating depression scale (SDS).

RESULTSAll the patients experienced significant pain reduction immediately after surgery. The scales of short MPQ and VAS at pre-operation, 6-month and 12-month follow-up were 31.5 +/- 3.4 and 8.8 +/- 1.5, 6.5 +/- 1.9 and 2.5 +/- 2.2, 7.1 +/- 2.1 and 2.9 +/- 1.9, respectively. The postoperative scores comparing to pre-operative scores showed a statistically significant difference (P < 0.01). The depression and anxiety state was also significantly relieved. At 12-month follow-up 6 patients had complete pain relief, 11 had excellent results with more than 75% pain relief, 17 had good results with more than 50% pain relief (73.9%). The main postoperative complications were transient slight hemiplegia (8), hypesthesia and paresthesia (15), a bearing down feeling of affected extremity (6), and deep sensory disability in the lower limbs (4) on the operated side. Because of the long time and prone position of the operation, 13 cases had a transient hyperalgesia in the upper chest.

CONCLUSIONDREZ coagulation is a safe and effective procedure in the treatment of deafferentation pain syndromes.

Adult ; Aged ; Causalgia ; pathology ; physiopathology ; surgery ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Neurosurgical Procedures ; methods ; Pain Measurement ; Spinal Nerve Roots ; surgery ; Treatment Outcome

Complex Regional Pain Syndromes (CRPS) type I and type II are neuropathic pain conditions that are being increasingly recognized in children and adolescents. The special distinctive features of pediatric CRPS are the milder course, the better response to treatment and the higher recurrence rate than that of adults and the lower extremity is commonly affected. We report here on a case of pediatric CRPS that was derived from ankle trauma and long term splint application at the left ankle. The final diagnoses were CRPS type I in the right upper limb, CRPS type II in the left lower limb and unclassified neuropathy in the head, neck and precordium. The results of various treatments such as medication, physical therapy and nerve blocks, including lumbar sympathetic ganglion blocks, were not effective, so implantation of a spinal cord stimulator was performed. In order to control the pain in his left lower limb, one electrode tip was located at the 7th thoracic vertebral level and two electrode tips were located at the 7th and 2nd cervical vertebral levels for pain control in right upper limb, head, neck and right precordium. After the permanent insertion of the stimulator, the patient's pain was significantly resolved and his disabilities were restored without recurrence. The patient's pain worsened irregularly, which might have been caused by psychological stress. But the patient has been treated with medicine at our pain clinic and he is being followed up by a psychiatrist.
Adolescent ; Adult ; Ankle ; Causalgia ; Child ; Complex Regional Pain Syndromes ; Diagnosis ; Electrodes ; Ganglia, Sympathetic ; Head ; Humans ; Lower Extremity ; Neck ; Nerve Block ; Neuralgia ; Pain Clinics ; Psychiatry ; Recurrence ; Spinal Cord Stimulation* ; Spinal Cord* ; Splints ; Stress, Psychological ; Upper Extremity

The complex regional pain syndromes (CRPS I and CRPS II), also known as reflex sympathetic dystrophy and causalgia, have been recognized for the past 2,500 years. Despite its long history, the diagnosis and treatment of CRPS are still challenging. These syndromes can be characterized by discrete sensory, motor, and autonomic findings, but many patients with CRPS continue to suffer for years without the diagnosis. Although much progress has been made in the understanding of CRPS, many questions still remain unanswered. CRPS is probably a disease of the central nervous system. Yet, peripheral inflammatory processes, abnormal sympathetic- afferent coupling, and adrenoreceptor pathology may also be part of the picture. A close multidisciplinary approach amongst the pain medicine consultants, psychologist, physical and occupational therapists, and neurologist is necessary to achieve the maximum treatment outcomes. If conventional treatment (e.g. pharmacotherapy) fails to show a significant response within 12 weeks, an interventional technique such as spinal cord stimulation (SCS) needs to be tried. The current concepts of CRPS could be replaced by a new mechanism-based term or group of terms in the near future leading to improved clinical guidelines. This article reviews the different aspects of CRPS including its definition, classification, epidemiology and natural history, clinical presentation, pathophysiology and management.
Causalgia ; Central Nervous System ; Classification ; Complex Regional Pain Syndromes ; Consultants ; Diagnosis* ; Epidemiology ; Humans ; Natural History ; Pathology ; Psychology ; Reflex Sympathetic Dystrophy ; Spinal Cord Stimulation