OBJECTIVE: This study aimed to determine the efficacy of evening primrose oil versus dinoprostone gel as a cervical priming agent prior to operative hysteroscopy.

METHODOLOGY: Nine patients were randomized to receive either oral Evening Primrose Oil 1000mg/capsule one capsule three times a day for 7 days (n=4) versus 500 mcg intracervical dinoprostone gel 12 hours (n=5) prior to the procedure. The primary outcome measures were baseline cervical width prior to operative hysteroscopy. The secondary outcomes were surgeons' subjective assessments of insertion difficulty, number of patients requiring cervical dilatation, duration of cervical dilatation, pre-operative pain, adverse effects and complications.

RESULTS: Both agents, Evening primrose oil and dinoprostone gel, were effective for cervical dilatation with a mean cervical diameter of 8.0 ± 1.4mm and 8.2 ± 1.3mm, respectively (P=0.832). There were no significant difference in the mean cervical diameter, ease of insertion of operative hysteroscope, time required for and number of patients requiring cervical dilatation. More patients in the dinoprostone complained of hypogastric pain prior to the procedure. No perioperative complications were observed in both groups.

CONCLUSION: Both oral Evening primrose oil and intracervical dinoprostone gel were equally effective in inducing proper cervical priming prior to operative hysteroscopy. Nevertheless, Evening primrose oil may be superior due to its oral route, reduced cost, patient convenience and acceptability.

Human ; Female ; Primula ; Dinoprostone ; Cervix Uteri ; Hysteroscopy

OBJECTIVE

This study aimed to determine the efficacy of evening primrose oil versus dinoprostone gel as a cervical priming agent prior to operative hysteroscopy.

METHODOLOGY

Nine patients were randomixed to receive either oral Evening Primrose Oil 1000mg/capsule one capsule three times a day for 7 days (n=4) versus 500 mcg intracervical dinoprostone gel 12 hours (n=5)prior to the procedure. The primary outcome measures were baseline cervical width prior to operative hysteroscopy. The secondary outcomes were surgeons' subjective assessments for insertion difficulty, number of patients requiring cervical dilatation, duration of cervical dilatation, pre-operative pain, adverse effects and complications.

RESULTS

Both agents, Evening primrose oil and dinoprostone gel, were effective for cervical dilatation with a mean cervical diameter of 8.0+1.4 mm and 8.2+1.3 mm, respectively (P=0.832). There are no significant difference in the mean cervical diameter, ease of insertion of operative hysteroscope, time required for and number of patients requiring cervical dilatation. More patients in the dinoprostone complained of hypogastric pain prior to the procedure. No perioperative complications were observed in both groups.

CONCLUSION

Both oral Evening primrose oil and intracervical dinoprostone gel were equally effective in inducing proper cervical priming prior to operative hysteroscopy. Nevertheless, Evening primrose oil may be superior due to its oral route, reduced cost, patient convenience and acceptability.

Dinoprostone ; Evening Primrose Oil

This is a case of a 23 years-old single, nulligravid with primary amenorrhea, sexual infantilism, tall stature who presented with abdominal enlargement. Ultrasound showed a small uterus, thin tall stature who presented with abdominal enlargement. Ultrasound showed a small uterus, thin endometrium, bilateral adnexal solid masses. Extensive diagnostic work-up for the etiology of the priamry amenorrhea led to the diagnosis of Swyer syndrome. Karyotyping showed 46, XY. On laparotomy, both gonads were solid with tumor implants on the omentum, mesentery and serosa of the small uterus. Total hysteroctomy with bilateral salpingo-gonadectomy, infracolic omentectomy, tumor debulking and biopsy of implants were done. Histopathologic report showed yolf sac (endodermal sinus tumor), both gonads and aforementioned implants. The risk of neoplasia in such cases is discussed.
Human ; Female ; Young Adult ; ENDODERMAL SINUS TUMOR ; GONADAL DYSGENESIS, 46,XY ; GONADAL DYSGENESIS ; GONADOBLASTOMA ; ENDODERMAL SINUS TUMOR