Thyroid carcinoma is closely related to environmental factors. Gene mutations and molecular biological changes of gland tissue caused by environmental changes are important factors inducing thyroid carcinoma. Although the molecular mechanism of thyroid carcinoma has not been fully elucidated,increasingly specific genetic changes and molecular markers for thyroid carcinoma have been discovered with the development of molecular biology techniques. This article reviews the recent progresses on the etiology,specific molecular markers,diagnosis and targeted therapies of thyroid carcinoma,so as to provide theoretical support for the clinical diagnosis and treatment of thyroid carcinoma.

Objective:To study the effect of doctor-nurse cooperation responsibility system in medical care in patients with pulmonary thromboembolism.Methods:A total of 208 patients with suspected pulmonary thromboembolism were selected as research objects from Oct 1 st, 2017 to Oct 1 st, 2018. Among them, there were 144 patients with high risk pulmonarythromboembolism, 64 patients with diagnosed pulmonary thromboembolism. They were divided into control group and experimental group randomly by admission time, 104 patients for each group. Therein, there were 74 patients with high risk pulmonary thromboembolism, and 30 patients with diagnosed pulmonary thromboembolism in control group, 70 patients with high risk pulmonary thromboembolism, and 34 patients with diagnosed pulmonary thromboembolism in study group. The patients in control group were given conventional nursing management mode and patients in study group were given all-in-one nursing mode in medical care. The nursing effects were compared between the two groups. Results:The missing report rate in the control group was 8.1% (6/74), high risk identification leakage rate was 12.2% (9/74), the preventive drug treatment leakage rate was 8.1% (6/74), and the physical preventive leakage treatment rate was 9.5% (7/74). The experimental group about the missing report rate was 2.9% (2/70), high risk identification leakage rate was 4.3%(3/74), The preventive drug treatment leakage rate was 2.9% (2/70), physical preventive leakage treatment rate was 4.3% (3/70), all of these items were lower than those of the control group, and patient satisfaction of the high risk patients had significant differences between the two groups ( χ2 values were 6.08-7.51, P<0.05). And the inspection checklist leakage rate of the control group [43.3% (13/30)] was higher than that of the experimental group [17.6% (6/34)], the health education awareness rate of the control group was [36.7% (11/30)], lower than that of the experimental group [91.2%(31/34)], patient satisfaction of the control group [40.0% (12/30)] was lower than that of the experimental group [94.1% (32/34)], these items had significant differences between the two groups ( χ2 values were 10.26, 4.57, 4.22, P<0.05). Conclusions:Doctor-nurse cooperation responsibility system in medical care have improved the implementation rate of prevention and treatment intervention of pulmonary thromboembolism, and improve the health education awareness rate and satisfaction rate of patients. It makes the prevention and control management of pulmonary thromboembolism for patients more effectively.