1.Exploration and Practice of Performance Evaluation System for Large Medical Equipment Based on Internet of Things Technology.
Chang SU ; Caixian ZHENG ; Linling ZHANG ; Yunming SHEN ; Kai FAN ; Tingting DONG ; Hangyan ZHAO ; Xiaofeng WANG ; Dawei QIAO ; Kun ZHENG
Chinese Journal of Medical Instrumentation 2025;49(2):191-196
Medical equipment, as an important indicator of smart hospital evaluation, plays a vital role in hospital operations. To ensure the safe and efficient operation of medical equipment, a reasonable performance evaluation system is indispensable. This study introduces a platform based on Internet of Things (IoT) technology that connects medical devices and collects data, achieving standardized and structured data processing, and supporting online operational supervision. Through the Delphi method, a performance evaluation system for large medical equipment is constructed, including 4 primary indicators and 22 secondary indicators. DICOM data acquisition devices are used to achieve functions such as efficiency analysis, benefit analysis, usage evaluation, and decision-making support for medical equipment. The study is still in its early stages, and in the future, it is expected to integrate more types of equipment, achieve rational resource allocation, and significantly impact decision-making for the development of public hospitals.
Internet of Things
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Delphi Technique
2.Study on the Clinical Application Effect of Low-Field Infant MRI.
Caixian ZHENG ; Siwei XIANG ; Chang SU ; Linyi ZHANG ; Can LAI ; Tianming YUAN ; Lu ZHOU ; Yunming SHEN ; Kun ZHENG
Chinese Journal of Medical Instrumentation 2025;49(5):501-506
OBJECTIVE:
Evaluate the clinical application effect of low-field infant MRI.
METHODS:
Using literature review, expert consultation, and two rounds of Delphi to determine the evaluation index system. Then retrospectively analyze and compare the data of low-field infant MRI and high-field MRI from January 2023 to December 2024.
RESULTS:
There is a certain gap between low-field infant MRI and high-field MRI in terms of signal-to-noise ratio, image uniformity, software system reliability, scanning time, user interface friendliness and image result consistency. However, there was no difference in terms of spatial resolution and image quality. The noise, hardware system reliability, mean time between failure and the rate of examination completed without sedation are better than that of high-field MRI.
CONCLUSION
Low-field infant MRI meets needs of clinical diagnostic and has stable performance. It can be used as a routine screening tool for brain diseases near the bed.
Magnetic Resonance Imaging/methods*
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Humans
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Infant
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Retrospective Studies
;
Signal-To-Noise Ratio
;
Reproducibility of Results
;
Brain Diseases/diagnostic imaging*
;
Brain/diagnostic imaging*
;
Software
3.Reduction of head and neck lymphedema by placing dose limiting rings in the anterior and posterior regions of the neck for treating early nasopharyngeal carcinoma using intensity-modulated radiotherapy:A dosimetric perspective
Kai LIAO ; Yunhong TIAN ; Ronghui ZHENG ; Caixian HE ; Jiyong PENG ; Huijun LI
The Journal of Practical Medicine 2024;40(12):1659-1664
Objective To establish an optimal limiting dose for dose limiting rings placed in the anterior and posterior regions of the neck for reducing head and neck lymphedema under intensity-modulated radiation therapy(IMRT)for early nasopharyngeal carcinoma(NPC)from a dosimetric perspective.Method Fifteen newly diagnosed early-stage nasopharyngeal carcinoma patients who underwent CT localization for radiotherapy at the Cancer Hospital of Guangzhou Medical University from January to September 2022 were included in the study.Each case was designed with five sets of radiotherapy plans.Plan A consisted of conventional unlimited-field plans,while Plans B-E consisted of limited-field plans with dose constraints set at 20,18,16,and 14 Gy,respectively,with the remaining parameters consistent with Plan A.The impact on target coverage and organ-at-risk constraints was evaluated through variance analysis and pairwise multiple comparisons using a randomized block design to determine the optimal dose limits.Results The gradient of 16Gy was determined as the optimal dose limiting cutoff point for achieving the balance between target coverage and organ limiting dose.Compared with the conventional plan,The plans with the placement of a cervical anterior and posterior dose limiting ring(16Gy)did not change the target dose coverage(P>0.05),but only yielded a slight change in the homogeneity index(P<0.05).It did not cause any changes of the dosage in the inner ear,mandible,and brainstem(all P>0.05),but lead to statisti-cally significant reductions in the oral cavity,throat,and thyroid(all P<0.05).It caused a slight increase of the dose in the parotid gland and spinal cord(both P<0.05),but the increased dose was anyhow within the tolerance range.Conclusion The dosimetric investigation determines an optimal dose limit cutoff point for the cervical ante-rior and posterior dose limiting rings.It is expected to provide a design method for IMRT plans to reduce head and neck lymphedema after radiotherapy for early NPC.
4.Study on the differences of clinical application in pediatric patients for different brands infrared ear thermometers
Lin WANG ; Caixian ZHENG ; Linxiang HE ; Kun ZHENG ; Baiping LI ; Yunming SHEN
China Medical Equipment 2024;21(6):214-216
Objective:To explore the differences in the clinical application of different brands of infrared ear thermometers in pediatric patients,and to guide the rational use of infrared ear thermometers.Methods:A total of 164 inpatients and outpatients who received treatment in the Children's Hospital of Zhejiang University School of Medicine from May 2023 to July 2023 were randomly selected,and three different brands of ear thermometers were used to measure the ear temperature of the children in the same measurement method.The differences in temperature and time measured by different brands of ear thermometers in children of different ages were compared.Results:The temperature and time measurements of the three ear thermometers were compared,the difference was statistically significant(F=5.007,264.988,P<0.05).The temperature of children aged≤3 months was measured by the three ear thermometers,and the difference was statistically significant(F=3.868,P<0.05).there was no difference in children aged over 3 months.Conclusion:For children of different ages,medical institutions can make choices based on the comprehensive consideration of the use cost,the speed of measurement time and other factors.For children aged over 3 months,choose product B with lower cost and faster measurement time,for children aged 0-3 months,it is recommended to choose product A with more accurate temperature measurement values.
5.Construction of a skill training practice system for port health quarantine
Ming XIAO ; Xianfeng WU ; Haibin ZOU ; Caixian LI
Chinese Journal of Medical Education Research 2023;22(8):1127-1132
Based on cognitive psychology, the business attributes of port health quarantine, the requirements for team building, the current status of skill training. This article proposes to strengthen the training of port health quarantine skills. Under the guidance of medical licensing examination for public health, it is recommended to enhance the construction of a standardized skill training practice system, establish a basic skill training center and a field operation training site, develop new skill training courses, innovate skills training and teaching methods, and build a team of high-quality skill training teachers, thereby constructing a standardized skill training and practice system for port health quarantine. The preliminary establishment of the skill training system for port health quarantine at Huangpu Customs shows the feasibility and effectiveness of the construction of skill training and practice system.
6.Risk factors for medical adhesive-related skin injury at peripherally inserted central catheters catheterization site in patients with tumor palliative care
Chinese Journal of Modern Nursing 2023;29(14):1917-1920
Objective:To analyze risk factors of medical adhesive-related skin injury (MARSI) at the site of peripherally inserted central catheters (PICC) in patients with tumor palliative care.Methods:A total of 315 patients who underwent tumor palliative care in the People's Hospital of Guangxi Zhuang Autonomous Region from June 2019 to June 2020 were selected as the research objects by the convenient sampling method, and they were divided into the occurrence group and the non-occurrence group according to whether they had MARSI. The differences of general and clinical data between the two groups were compared. Logistic regression analysis was used to analyze the risk factors of MARSI.Results:Among 315 tumor palliative care patients, 100 cases (31.75%) had MARSI at PICC catheterization site. Compared with the non-occurrence group, the occurrence group showed an increase in the proportion of PICC puncture site on the medial side of the biceps brachii, PICC catheterization frequency greater than or equal to 2 times, large angle removal of the dressing, semi permeable dressing type, dressing replacement frequency of 2 times per week and delayed maintenance of PICC catheters, and the differences were statistically significant ( P<0.05). Logistic regression analysis showed that PICC puncture site on the medial side of the biceps brachii, PICC catheterization frequency greater than or equal to 2 times, large angle removal of the dressing, semi permeable dressing type, dressing replacement frequency of 2 times per week and delayed maintenance of PICC catheters were all risk factors for MARSI at the PICC catheterization site in tumor palliative treatment patients ( P<0.05) . Conclusions:There are many risk factors for MARSI at the PICC catheter site in patients undergoing tumor palliative care and targeted preventive measures need to be taken in clinical practice to reduce MARSI.
7.Evidence-based practice of radiotherapy-induced oral mucositis care blueprint based on action studies
Yan JIA ; Caixian YE ; Hongying PAN ; Xuefeng CHEN ; Xiaowei FU
Chinese Journal of Modern Nursing 2022;28(11):1483-1489
Objective:To formulate a blueprint for the care of radiotherapy-induced oral mucositis (RIOM) in patients with nasopharyngeal carcinoma, to implement and observe the effect.Methods:Using the convenient a sampling method, a total of 182 patients with nasopharyngeal carcinoma who underwent radiotherapy and chemotherapy in Cancer Hospital of The University of China Academy of Sciences from July 2019 to June 2020 were selected as the research objects. A total of 91 patients from July to December 2019 were set as the control group and they received conventional radiotherapy care. A total of 91 patients from January to June 2020 were set as the intervention group. On the basis of the control group, the intervention group adopted conventional radiotherapy nursing and implemented the care blueprint based on the action study method. The incidence, severity and pain of RIOM were compared between the two groups.Results:In the 3rd to 5th week of radiotherapy, the incidences of RIOM in the intervention group were lower than those in the control group, and the differences were statistically significant ( P<0.05) . At week 3 and after radiotherapy, the severity of RIOM in the intervention group were less than those in the control group, and the differences were statistically significant ( P <0.05) . At the end of radiotherapy, the degree of oral pain in the intervention group was lighter than that in the control group, and the difference was statistically significant ( P< 0.05) . Conclusions:RIOM care blueprint constructed in this study is scientific and valid. Evidence-based RIOM care blueprint can reduce the incidence and severity of RIOM in nasopharyngeal cancer patients and relieve oral pain, which is worthy of clinical application.
8.Establishment of UPLC Fingerprint of Pyrrosia petiolosa from Southwest China and Content Determination of Phenolic Acids Component
Yunjing QIU ; Caixian SUO ; Liye PAN ; Minyou HE ; Xiangdong CHEN ; Guowei LI
China Pharmacy 2021;32(9):1093-1099
OBJECTIVE:To esta blish a UPLC fingerprint of Pyrrosia petiolosa from southwest China ,and to determine the contents of 4 kinds of phenolic acids (neochlorogenic acid ,caffeic acid ,chlorogenic acid and cryptochlorogenic acid ). METHODS:The determination was performed on Waters Cortecs T 3 C18 column(100 mm×2.1 mm,1.6 μm)with mobile phase consisted of methanol- 0.1% phosphoric acid (gradient elution )at the flow rate of 0.35 mL/min. The detection wavelength was set at 326 nm. The column temperature was 30 ℃,and injection volume was 1 μL. UPLC method was used to establish the UPLC fingerprint of P. petiolosa in combination with the Similarity Evaluation System of TCM Chromatographic Fingerprints (2012 edition). Cluster analysis and principle component analysis (PCA)were performed by using SPSS 20.0 software. The contents of 4 kinds of phenolic acids in 20 batches of P. petiolosa were determined by external standard method. RESULTS :There were 9 common peaks for the UPLC fingerprint of P. petiolosa . Peaks 1,3,4,5 and 9 were identified as neochlorogenic acid ,caffeic acid,chlorogenic acid ,cryptochlorogenic acid and isochlorogenic acid C ,respectively. RSDs of the relative retention time of each peak in different batches of P. petiolosa were 0-0.68%,and the RSDs of the relative peak area were 0-62.35%. The similarities between the fingerprint of 20 batches of medicinal materials and the control chromatogram were not less than 0.990. The result of cluster analysis showed that P. petiolosa from different regions could be sorted into three species. Results of PCA showed the differences among P. petiolosa from different regions. The linear range of neochlorogenic acid ,caffeic acid ,chlorogenic acid and cryptochlorogenic acid were 0.61-61.41,0.18-17.60,2.00-200.11,0.62-61.51 μ g/mL (R2>0.999 9). RSDs of precision , reproducibility and stability tests were all lower than 2.00%. The recoveries were 96.23%-98.17%(RSD=0.96%-2.28%, n=6). Among 20 batches of samples ,the contents of above 4 kinds of phenolic acids were 0.385 3-1.891 9,0.018 0-0.129 5,2.569 5-10.676 0,0.563.5-1.860 5 mg/g. CONCLUSIONS : The established UPL C fingerprint could reflect the main chemical constituents of P. pedunculata . Phenolic acids could be used as the main evaluation indexes for the quality of P. petiolosa . The quality order of P. petiolosa from southwest China was Chongqing product>Sichuan product >Guizhou product.
9.Effects of two common acellular methods on the physicochemical properties of dermal acellular matrix.
Caixian YANG ; Jiqiang GUO ; Jinghui WANG ; Jiayu FAN ; Yanxue XING ; Li ZHANG ; Meiwen AN
Journal of Biomedical Engineering 2021;38(5):911-918
At present, acellular matrix is an effective replacement material for the treatment of skin damage, but there are few systematic evaluation studies on its performance. The experimental group of this study used two decellularization methods to prepare the matrix: one was the acellular matrix which sterilized with peracetic acid first (0.2% PAA/4% ethanol solution) and then treated with hypertonic saline (group A), the other was 0.05% trypsin/EDTA decellularization after γ irradiation (group B); and the control group was soaked in PBS (Group C). Then physical properties and chemical composition of the three groups were detected. Hematoxylin eosin (HE) staining showed that the acellular effect of group B was good. The porosity of group A and B were both above 84.9%. In group A, the compressive modulus of elasticity was (9.94 ± 3.81) MPa, and the compressive modulus of elasticity was (12.59 ± 5.50) MPa in group B. There was no significant difference between group A or B and group C. The total content of collagen in acellular matrix of group A and B was significantly lower than that of group C (1. 662 ± 0.229) mg/g, but there was no significant difference in the ratio of collagen Ⅰ/Ⅲ between group B and group C. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) showed that there was no significant difference in microstructure. Qualitative detection of fibronectin and elastin in each group was basically consistent with that in group C. Therefore, acellular matrix of group B had better performance as scaffold material. The experimental results show that the acellular matrix prepared by γ-ray sterilization and decellularization of 0.05% Trypsin enzyme/EDTA could be used for the construction of tissue-engineered skin. It could also provide reference for the preparation and mounting of heterogeneous dermal acellular matrix. It was also could be used for electrostatic spinning or three-dimensional printed tissue engineered skin scaffold which could provide physical and chemical parameters for it.
Acellular Dermis
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Cells, Cultured
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Extracellular Matrix
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Porosity
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Tissue Engineering
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Tissue Scaffolds
10.Effects of Perfusion Velocity on Suspended Cells in Microchannels
Yanxue XING ; Hui SONG ; Caixian YANG ; Jiayu FAN ; Meiwen AN
Journal of Medical Biomechanics 2021;36(6):E910-E915
Objective To establish a finite element model of cell perfusion culture, and study the effect of different perfusion speeds on the movement of suspended cells. Methods The two-dimensional (2D) model of cell and microchannels was established using COMSOL Multiphysics and meshed. Three groups were established according to the perfusion speed, namely, u0=0.196 mm/s, u1=0.117 mm/s, u2=0.04 mm/s. The fluid-structure interaction module was used for calculation. Results The flow field distribution in the microchannel was relatively uniform. During the equal period of time, the ratio of cell suspension perfusion speed was u0∶u1∶u2=5∶3∶1, and the ratio of cell displacement in the microchannel was D0∶D1∶D2=4.1∶ 2.9∶1. When the speed was proportional, the displacement of cells also roughly followed the corresponding proportional change. With the increase of perfusion speed, stress concentration in cells during movement would occur. The stress and fluid shear force (FSS) of cells during movement were within the safe value range, and cell destruction would not occur. Conclusions The suspended cells can enter into the microchannel without injury at a certain perfusion speed. Perfusion techniques can be used in cell implantation of in vitro tissue engineering products.

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