1.Predictors of blood loss, operative time, and length of stay in adult spinal deformity surgery: a retrospective cohort study in Southeastern United States
Anthony E. BISHAY ; Harsh JAIN ; Hani CHANBOUR ; Jeffrey W. CHEN ; Tyler METCALF ; Alexander T. LYONS ; Amir M. ABTAHI ; Iyan YOUNUS ; Byron F. STEPHENS ; Scott L. ZUCKERMAN
Asian Spine Journal 2025;19(6):904-915
Methods:
Inclusion criteria: ≥5-level fusion, sagittal/coronal deformity, and minimum 2-year follow-up. Primary outcomes were the highest quartile of EBL (mL), operative time (minutes), and LOS (days). EBL was calculated based on the hemoglobin drop. Bivariate analysis and multivariable logistic regression were performed, controlling for age, comorbidities, and preoperative radiographic parameters.
Results:
Among 238 patients (mean age, 63.4±17.4 years), the highest EBL quartile (2,594.0±1,550.5 mL) had more three-column osteotomies (3CO) (30.5% vs. 14.8%, p=0.008). Multivariable predictors of highest EBL were older age (odds ratio [OR], 1.03; p=0.039) and 3CO (OR, 3.60; p=0.007). The highest operative time quartile (618.9±99.4 minutes) had more 3CO (27.1% vs. 15.3%, p=0.041) and higher rod fracture rates (30.5% vs. 15.8%, p=0.014). Multivariable predictors of the highest operative time were higher total instrumented levels (TIL) (OR, 1.26; p<0.001) and older age (OR, 1.05; p=0.003). The highest LOS quartile (14.5±18.5 days) had more 3CO (27.3% vs. 14.3%, p=0.045). The multivariable predictor of highest LOS was higher TIL (OR, 1.23; p<0.001).
Conclusions
Three-column osteotomy was the strongest predictor of perioperative morbidity in ASD surgery, consistently associated with higher blood loss, longer operative times, and prolonged hospital stays. Recognizing its impact can inform surgical strategies to improve patient outcomes.
2.Diagnosing ectopic pregnancy in the emergency setting.
Robert LEE ; Carolyn DUPUIS ; Byron CHEN ; Andrew SMITH ; Young H KIM
Ultrasonography 2018;37(1):78-87
Ectopic pregnancy is the implantation of a fertilized egg outside the uterine endometrial cavity. For women presenting to the emergency department with abdominal pain and/or vaginal bleeding, ectopic pregnancy is an important diagnostic consideration. The diagnosis is made based on laboratory values and ultrasound imaging findings. The ultrasound appearance of both normal early pregnancy and ectopic pregnancy are variable and often subtle, presenting diagnostic challenges for radiologists. This pictorial essay describes and illustrates the sonographic findings of ectopic pregnancy and reviews the differential diagnoses that can mimic ectopic pregnancy on ultrasound. With the possibility of medical management, the value of early detection and prompt initiation of treatment has increased in improving clinical outcomes and preventing the complications of ectopic pregnancy.
Abdominal Pain
;
Diagnosis
;
Diagnosis, Differential
;
Emergencies*
;
Emergency Service, Hospital
;
Female
;
Humans
;
Methotrexate
;
Pregnancy
;
Pregnancy, Ectopic*
;
Ultrasonography
;
Uterine Hemorrhage
;
Zygote
3.Ultrasonography of intrauterine devices.
Kristina M NOWITZKI ; Matthew L HOIMES ; Byron CHEN ; Larry Z ZHENG ; Young H KIM
Ultrasonography 2015;34(3):183-194
The intrauterine device (IUD) is gaining popularity as a reversible form of contraception. Ultrasonography serves as first-line imaging for the evaluation of IUD position in patients with pelvic pain, abnormal bleeding, or absent retrieval strings. This review highlights the imaging of both properly positioned and malpositioned IUDs. The problems associated with malpositioned IUDs include expulsion, displacement, embedment, and perforation. Management considerations depend on the severity of the malposition and the presence or absence of symptoms. Three-dimensional ultrasonography has proven to be more sensitive in the evaluation of more subtle findings of malposition, particularly side-arm embedment. Familiarity with the ultrasonographic features of properly positioned and malpositioned IUDs is essential.
Contraception
;
Contraceptive Devices, Female
;
Hemorrhage
;
Humans
;
Intrauterine Devices*
;
Pelvic Pain
;
Recognition (Psychology)
;
Ultrasonography*
4.The role of androgen receptor gene CAG polymorphism in prostate cancer
Yue CHEN ; Yongzhi TANG ; Hui MENG ; J BEILIN ; D J ZAJAC ; N J FAVALORO ; R DAVEY ; K BYRON ; H HAREWOOD
Journal of Clinical Urology 2001;16(2):51-53
Purpose:To further assess the role of androgen receptor gene CAG polymorphism in prostate cancer. Methods:DNA from 358 patients with prostate cancer were assayed for the number of CAG repeats. The length of CAG triplets and different clinical parameters were evaluated including age, PSA, stage, grade. Results:Only significant association between age at diagnosis and the length of CAG repeats was observed(P=0.007,γ=0.114).Conclusions:It was revealed from this study that the decreased number of AR gene CAG triplets was associated with the younger patient with prostate cancer at diagnosis.

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