1.Expert consensus on endobronchial balloon occlusion in the treatment of hemoptysis (2025 edition).
Chinese Journal of Internal Medicine 2025;64(11):1055-1064
Hemoptysis is a serious medical emergency associated with high mortality rates. Notably, it poses significant therapeutic challenges owing to the complexities in rapidly identifying the bleeding site and underlying cause. In severe cases, it can lead to death by asphyxia, thus necessitating prompt intervention. Bronchoscopy-guided endobronchial balloon occlusion (EBBO) is a vital procedure for blocking the bleeding bronchus, allowing time for subsequent embolization of the responsible vessel and definitive treatment. While traditional techniques for EBBO are intricate and demanding, recent advancements in balloon technology, along with procedural refinements, have simplified the process, reduced operation times, and enhanced medical staff proficiency. Nevertheless, a lack of standardized protocols and technical guidelines has hindered the widespread adoption of this technique in China. Accordingly, the Internal Medicine of Chinese Medical Association convened a group of experts to develop the "Expert consensus on endobronchial balloon occlusion in the treatment of hemoptysis (2025 edition)" to standardize this procedure. This consensus, grounded in evidence-based medicine and clinical practice both domestically and internationally, covers seven essential elements: treatment strategies, equipment, indications and contraindications, preoperative preparation, technical procedures and specifications, integration with other therapeutic techniques, efficacy assessment, and follow-up. By offering comprehensive guidance, the consensus aims to standardize and promote the use of EBBO for hemoptysis management in China.
Humans
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Hemoptysis/therapy*
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Balloon Occlusion/methods*
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Bronchoscopy
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Consensus
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Evidence-Based Medicine
2.Thermal Ablation of Pulmonary Nodules by Electromagnetic Navigation Bronchoscopy Combined With Real-Time CT-Based 3D Fusion Navigation:Report of One Case.
Yuan XU ; Qun LIU ; Chao GUO ; Yi-Bo WANG ; Xiao-Fang WU ; Chen-Xi MA ; Gui-Ge WANG ; Qian-Shu LIU ; Nai-Xin LIANG ; Shan-Qing LI
Acta Academiae Medicinae Sinicae 2025;47(1):137-141
A nodule in the right middle lobe of the lung was treated by a combination of cone-beam CT,three-dimensional registration for fusion imaging,and electromagnetic navigation bronchoscopy-guided thermal ablation.The procedure lasted for 90 min,with no significant bleeding observed under the bronchoscope.The total radiation dose during the operation was 384 mGy.The patient recovered well postoperatively,with only a small amount of blood in the sputum and no pneumothorax or other complications.A follow-up chest CT on the first day post operation showed that the ablation area completely covered the lesion,and the patient was discharged successfully.
Humans
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Bronchoscopy/methods*
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Catheter Ablation/methods*
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Cone-Beam Computed Tomography
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Electromagnetic Phenomena
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Imaging, Three-Dimensional
;
Lung Neoplasms/diagnostic imaging*
;
Tomography, X-Ray Computed
3.Endobronchial Metastasis From Rectal Cancer Treated by High-Frequency Electrocautery Ablation via Bronchoscope and Targeted Drugs:Report of One Case.
Jian-Hua YUAN ; Zong-Zhou XIE ; Y U WEI-LING ; Rong-Hua CUI ; L I JIAN-WANG
Acta Academiae Medicinae Sinicae 2025;47(1):142-145
The lungs are the most common sites of metastases from non-pulmonarymalignancies. Endobronchial metastases are rare and have no specificity in clinical manifestations,thus being prone to misdiagnosis and delayed treatment.The common tumors associated with endobronchial metastasis are renal,breast,and colorectal cancers.This article reported one case of postoperative rectal cancer with endobronchial and lung metastases,which was relieved by high-frequency electrocautery ablation via bronchoscope,chemotherapy,and targeted drugs,aiming to provide a reference for clinical diagnosis and treatment.
Humans
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Rectal Neoplasms/pathology*
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Electrocoagulation/methods*
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Bronchial Neoplasms/drug therapy*
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Bronchoscopy
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Lung Neoplasms/secondary*
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Bronchoscopes
4.Clinical and bronchoscopy features of tracheobronchial tuberculosis in children.
Shuai PENG ; Guang-Li ZHANG ; Jing-Xian HONG ; Hao DING ; Chong-Jie WANG ; Jian LUO ; Zheng-Xiu LUO
Chinese Journal of Contemporary Pediatrics 2023;25(4):381-387
OBJECTIVES:
To study the clinical and bronchoscopic characteristics of tracheobronchial tuberculosis (TBTB) in children and to identify factors influencing residual airway obstruction or stenosis.
METHODS:
The clinical data of children with TBTB were retrospectively collected. The children were divided into two groups based on the last bronchoscopic result within one year of follow-up: a group with residual airway obstruction or stenosis (n=34) and a group without residual airway obstruction or stenosis (n=58). A multivariate logistic regression analysis was used to identify the factors influencing residual airway obstruction or stenosis in children with TBTB. Receiver operating characteristic (ROC) curves were used to analyze the predictive value of the factors influencing residual airway obstruction or stenosis in children with TBTB.
RESULTS:
A total of 92 children with TBTB were included, and the main symptoms were cough (90%) and fever (68%). In children under 1 year old, the incidence rates of dyspnea and wheezing were significantly higher than in other age groups (P<0.008). Chest CT findings included mediastinal or hilar lymph node enlargement (90%) and tracheobronchial stenosis or obstruction (61%). The lymphatic fistula type was the main type of TBTB observed bronchoscopically (77%). All children received interventional treatment, and the effective rate was 84%. During one year of follow-up, 34 children had residual airway obstruction or stenosis. The TBTB diagnostic time and the initiation of interventional treatment were significantly delayed in the group with residual airway obstruction or stenosis compared with the group without residual airway obstruction or stenosis (P<0.05). The multivariate logistic regression analysis showed that the TBTB diagnostic time was closely related to residual airway obstruction or stenosis in children (P<0.05). ROC curve analysis showed that at the cut-off value of 92 days of TBTB diagnostic time, the area under the curve for predicting residual airway obstruction or stenosis in children with TBTB was 0.707, with a sensitivity of 58.8% and a specificity of 75.9%.
CONCLUSIONS
The clinical manifestations of TBTB are nonspecific, and symptoms are more severe in children under 1 year old. TBTB should be suspected in children with tuberculosis and chest imaging indicating airway involvement. Delayed diagnosis of TBTB is associated with the development of residual airway obstruction or stenosis.
Infant
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Child
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Humans
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Bronchoscopy/methods*
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Constriction, Pathologic/complications*
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Bronchial Diseases/therapy*
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Retrospective Studies
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Tuberculosis/diagnosis*
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Airway Obstruction/therapy*
7.Application and Progress of Electromagnetic Navigation Bronchoscopy in Department of Thoracic Surgery.
Chao GUO ; Xiayao DIAO ; Cheng HUANG ; Yeye CHEN ; Ye ZHANG ; Shanqing LI
Chinese Journal of Lung Cancer 2022;25(2):118-123
Lung cancer ranks the first cancer-related morbidity and mortality in China. With the development and penetration of imaging technology, increasing small pulmonary peripheral Nodules (SPPNs) have been detected. However, precise location and diagnosis of SPPNs is still a tough problem for clinical diagnosis and treatment in department of thoracic surgery. With the development of electromagnetic navigation bronchoscopy (ENB), it provides a novel minimally invasive method for the diagnosis and treatment of SPPNs. In this review, we summarized the application and progress of ENB in preoperative positioning, diagnosis, and local treatment, then, discussed the clinical application of ENB in the hybrid operating room.
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Bronchoscopy/methods*
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Electromagnetic Phenomena
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Humans
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Lung Neoplasms/surgery*
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Multiple Pulmonary Nodules/diagnosis*
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Thoracic Surgery
8.In Vitro Fatigue Test of Lung Volume Reduction Loop.
Juan-Jie WU ; Shu-Han WANG ; Wen-Liang LIU ; Fu-Hui-Ling LIU ; Kui-Yuan ZHU ; Si-Rui PENG ; Jing-Li ZHOU ; Yao LIU ; Hong-Wei LIU
Chinese Journal of Medical Instrumentation 2022;46(3):332-335
Lung volume reduction loop uses bronchoscopic lung volume reduction(BLVR) technology to compress and collapse the necrotic emphysema tissue and exhaust the internal gas to achieve the purpose of lung volume reduction to treat emphysema. After the lung volume reduction loop is implanted into the human body, the compressed part of the lung tissue tends to expand with breathing, which makes the lung volume reduction loop expand into a linear trend periodically. Fatigue resistance is one of the most important performance indexes of the lung volume reduction loop. In the paper, Z-direction vibration fatigue machine was used to simulate the changes of human respiratory cycle movement to test the fatigue performance of lung volume reduction loop, which can provide some reference for the test method of in vitro fatigue performance of lung volume reduction related products in the future.
Bronchoscopy/methods*
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Emphysema/surgery*
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Humans
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Lung
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Pneumonectomy/methods*
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Pulmonary Emphysema/surgery*
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Treatment Outcome
9.Recent advances in diagnosis of pulmonary nodule.
Chinese Journal of Surgery 2022;60(5):498-503
With the popularization of health screening and the widespread use of low-dose computed tomography, the detection rate of lung nodules has increased year after year. However, the false positive rates testified by surgery of these lung nodules are still high. Therefore, it is vital in clinical practice to avoid overtreatment or undertreatment. But a series of problems on how to make an accurate diagnosis, how to reduce the psychological pressure of patients and follow up with regular imaging, how to clarify the indications for surgery and adopt the most minimally invasive diagnosis and treatment methods, etc. remain unsolved. Over the past decade, the diagnostic techniques for pulmonary nodules have improved significantly, including imaging progress such as the optimization of traditional imaging techniques (CT, MRI) and the emergence of new technologies (radiomics, artificial intelligence). In addition, histological improvements including percutaneous transthoracic needle biopsy, bronchoscopy, and minimally invasive surgical biopsy, etc. have brought more reliable and precise options for characterization of pulmonary nodules.
Artificial Intelligence
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Biopsy, Needle/methods*
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Bronchoscopy
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Humans
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Lung Neoplasms/diagnosis*
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Tomography, X-Ray Computed
10.Efficacy of bronchoscopic thermal vapor ablation in patients with heterogeneous emphysema and lobar quantification by three-dimensional ventilation/perfusion single-photon emission computed tomography/computed tomography: a prospective pilot study from China.
Wenjun ZHU ; Yuchen ZHANG ; Felix J F HERTH ; Dan LIU ; Hui ZHU ; Jingyu SHI ; Chujie ZHANG ; Gongshun TANG ; Fengming LUO
Chinese Medical Journal 2022;135(17):2098-2100

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