1.A case report of unilateral tibia and fibula oligometastasis from prostate cancer
Journal of Modern Urology 2026;31(6):603-605
Objective To investigate the diagnosis and treatment of oligometastatic prostate cancer with unilateral tibia and fibula involvement, so as to provide reference for the management of this condition. Case Report An 85-year-old male sought medical attention for left lower extremity swelling and pain.Diagnostic workup included computed tomography (CT), magnetic resonance imaging (MRI), pathological and immunohistochemical analysis of a left tibial biopsy, prostate biopsy, and a whole-body bone scan.These investigations confirmed prostate acinar adenocarcinoma with a Gleason score of 9 (4+5).The bone scan demonstrated foci of increased radiotracer uptake in the left tibia and fibula, establishing the final diagnosis of prostate cancer with unilateral oligometastasis to these bones.Following endocrine therapy, follow-up revealed a significant decrease in prostate-specific antigen (PSA) level along with shrinkage of the primary lesion on prostate MRI. Conclusion Prostate cancer can rarely manifest with distal limb oligometastases as its initial presentation, a condition prone to misdiagnosis as osteomyelitis or other bone disorders.This possibility should be considered and promptly screened in elderly males with unexplained bone pain.
2.A comparison of the Barthel Index with functional independence measures for assessing ability in the activities of daily living after a stroke
Qingqing ZHOU ; Jiajia SHI ; Boye NI
Chinese Journal of Physical Medicine and Rehabilitation 2021;43(7):602-606
Objective:To observe the relationship between extended Barthel index (EBI) values and functional independence measures (FIMs) in quantifying the ability in the activities of daily living (ADL) of stroke survivors.Methods:Eighty-six stroke survivors′ ADL ability was assessed using the FIM and the EBI and the results were compared.Results:The inter-rater reliability (ICC) of the EBI was 0.866 and the Spearman correlation coefficient relating the EBI and FIM results was 0.972. The 4 ADL functional levels of the EBI were strongly correlated with the 8 ADL functional levels of the FIMs ( χ2=187, P≤0.001). The complete dependence and extreme dependence ratings of the FIMs (18-35 points) corresponded to the EBI′s " completely needed" . Severe and moderate dependence (36-71 points) corresponded to a lot of help needed. Mild dependence, conditional independence or very mild dependence (72-107 points) corresponded to some help needed. Basic independence and complete independence (108-126 points) corresponded to self-care. Conclusions:The EBI has high reliability and good validity, and its 4 ADL functional levels correspond well with the FIMs′ 8 ADL function levels. The EBI has good clinical applicability.

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