1.Diagnostic Validity of the Comprehensive Attention Test in Patients With Attention-Deficit/Hyperactivity Disorder
Hyunju LEE ; Hannah HUH ; Woo Young KIM ; Eun Kyoung LEE ; Bum-Sung CHOI ; Bongseog KIM ; Hanik YOO
Journal of the Korean Academy of Child and Adolescent Psychiatry 2024;35(4):243-249
Objectives:
This study verified the diagnostic validity of the Comprehensive Attention Test (CAT) for attention-deficit/hyperactivity disorder (ADHD).
Methods:
A total of 336 participants were recruited in this study, including 168 patients with ADHD and 168 control group participants who were one-to-one matched for sex and age. We measured selective attention (visual and auditory), sustained attention, interferenceselective attention, divided attention, and working memory in the ADHD and control groups using the CAT. The sensitivity, specificity, positive predictive value, and negative predictive value of the CAT were calculated.
Results:
In this study, it was found that the sensitivity and specificity of the CAT were 0.879 and 0.846 in children, 0.855 and 0.838 in adolescents, and 0.800 and 0.733 in adults, respectively.
Conclusion
These results indicate that the CAT has a high diagnostic validity for ADHD from childhood to adulthood.
2.Beyond Attention-Deficit Hyperactivity Disorder:Exploring Psychiatric Comorbidities and Their Neuropsychological Consequences in Adults
Hyun Jae ROH ; Geon Ho BAHN ; Seung Yup LEE ; Yoo-Sook JOUNG ; Bongseog KIM ; Eui-Jung KIM ; Soyoung Irene LEE ; Minha HONG ; Doug Hyun HAN ; Young Sik LEE ; Hanik K YOO ; Soo-Young BHANG
Journal of the Korean Academy of Child and Adolescent Psychiatry 2023;34(4):275-282
Objectives:
This study aimed to identify the psychiatric comorbidity status of adult patients diagnosed with attention-deficit hyperactivity disorder (ADHD) and determine the impact of comorbidities on neuropsychological outcomes in ADHD.
Methods:
The study participants were 124 adult patients with ADHD. Clinical psychiatric assessments were performed by two boardcertified psychiatrists in accordance with the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. All participants were assessed using the Mini-International Neuropsychiatric Interview Plus version 5.0.0 to evaluate comorbidities. After screening, neuropsychological outcomes were assessed using the Comprehensive Attention Test (CAT) and the Korean version of the Wechsler Adult Intelligence Scale, Fourth Edition (K-WAIS-IV).
Results:
Mood disorders (38.7%) were the most common comorbidity of ADHD, followed by anxiety (18.5%) and substance use disorders (13.7%). The ADHD with comorbidities group showed worse results on the Perceptual Organization Index and Working Memory Index sections of the K-WAIS than the ADHD-alone group (p=0.015 and p=0.024, respectively). In addition, the presence of comorbidities was associated with worse performance on simple visual commission errors in the CAT tests (p=0.024).
Conclusion
These findings suggest that psychiatric comorbidities are associated with poor neuropsychological outcomes in adult patients with ADHD, highlighting the need to identify comorbidities in these patients.
3.How the COVID-19 Pandemic Affects the Mental Health of University Hospital Nurses?: Focusing on Resilience, Stress, Depression, Anxiety, and Sleep
Journal of Korean Neuropsychiatric Association 2023;62(1):54-62
Objectives:
This study aimed to explore how the coronavirus disease-2019 (COVID-19) pandemic affected the mental health of university hospital nurses with a focus on their resilience, stress, depression, anxiety, and sleep.
Methods:
A total of 220 nurses working at a university hospital in South Korea during the COVID-19 pandemic participated in this study. The collected data were subjected to analysis based on the percentage, mean, standard deviation, Kruskall-Wallis test, Mann-Whitney test, and Pearson correlation coefficient using the IBM SPSS Statistics 25 program.
Results:
The range of the Brief Resilience Scale was 1.3 to 5.0 (3.2±0.6), Perceived Stress Scale was 4 to 34 (18.6±5.3), Pittsburgh Sleep Quality Index was 2 to 17 (7.4±3.1), Patient Health Questionnaire was 0 to 18 (5.0±4.0), and General Anxiety Disorder-7 was 0 to 16 (3.4±3.4). The range of the difference in job stress before and after the COVID-19 pandemic outbreak was -5 to +7 (2.2±1.9). There was a negative correlation between the nurses’ resilience and stress, depression, anxiety, and sleep.
Conclusion
Most of the nurses experienced high levels of stress, depression, anxiety, and poor sleep quality during the COVID-19 pandemic. The mental health of nurses should be carefully monitored with interest, and various compensatory systems should be developed to help them cope with the situation.
4.The Loudness Dependence of Auditory Evoked Potentials is associated with the Symptom Severity and Treatment in Boys with Attention Deficit Hyperactivity Disorder
Eun Jin PARK ; Young-Min PARK ; Seung-Hwan LEE ; Bongseog KIM
Clinical Psychopharmacology and Neuroscience 2022;20(3):514-525
Objective:
The loudness dependence of the auditory evoked potential (LDAEP) is associated with central serotonergic neurotransmission. Recent studies have proposed that LDAEP is also influenced by dopaminergic activity. Evidence shows attention deficit hyperactivity disorder (ADHD) symptoms are associated with dopamine dysfunction. This study aimed to evaluate the relation between ADHD symptoms and LDAEP, as well as medication-mediated changes of LDAEP.
Methods:
A total of 38 male children (6−12 years old) with ADHD were analyzed in this study. Symptom severity was assessed using the ADHD rating scale (ARS) and the continuous performance test. To determine LDAEP, the auditory event-related potential was evaluated before medication. Changes in LDAEP were measured after 12 weeks of treatment with methylphenidate.
Results:
The subjects had a mean age of 9.24 ± 1.74 years with an average IQ of 109.4 ± 13.8. Before pharmacological treatment with methylphenidate, LDAEP was positively associated with the ARS score after adjusting for age and IQ (r = 0.592, p = 0.005). LDAEP was correlated with inattention (r = 0.522, p = 0.015) and hyperactivity-impulsivity (r = 0.6, p = 0.004). However, the LDAEP of 15 subjects decreased following methylphenidate treatment (Z = −1.988, p = 0.047).
Conclusion
In boys with ADHD, LDAEP appears to be associated with symptom severity. LDAEP showed a significant association with impulsivity and inattention. Importantly, LDAEP was shown to decrease after drug treatment. Our findings support the utility of LDAEP as a noninvasive and clinically useful method to assess symptom severity in children with ADHD.
5.Changes in Children with Autism Spectrum Disorder after Theraplay Application
Yoonyoung CHANG ; Bongseog KIM ; Miwon YOUN
Journal of the Korean Academy of Child and Adolescent Psychiatry 2021;32(3):112-117
Objectives:
This study identified changes in social communication and interaction among children with autism spectrum disorder (ASD) through Theraplay.
Methods:
This study included 20 children who were diagnosed with ASD by a child and adolescent psychiatrist and were recommended to undergo Theraplay in 2012–2017. The Marschak interaction method was used to identify and analyze the interactions between parents and their children. The Korean version of the Social Communication Questionnaire (K-SCQ) was used to evaluate symptoms of ASD. The Wilcoxon signed-rank test was used to compare the differences before and after Theraplay.
Results:
Upon comparing the differences in total K-SCQ scores, there were statistically significant changes (z=-3.269, p=0.001) in children with ASD. Changes were also confirmed in each category, namely social interaction, communication, and limited and repetitive behavior patterns (p=0.011, p=0.025, p=0.039, respectively).
Conclusion
This study found that Theraplay may cause significant changes in social communication in children with ASD. Further studies are needed to establish the effectiveness of Theraplay in children with ASD.
6.Changes in Children with Autism Spectrum Disorder after Theraplay Application
Yoonyoung CHANG ; Bongseog KIM ; Miwon YOUN
Journal of the Korean Academy of Child and Adolescent Psychiatry 2021;32(3):112-117
Objectives:
This study identified changes in social communication and interaction among children with autism spectrum disorder (ASD) through Theraplay.
Methods:
This study included 20 children who were diagnosed with ASD by a child and adolescent psychiatrist and were recommended to undergo Theraplay in 2012–2017. The Marschak interaction method was used to identify and analyze the interactions between parents and their children. The Korean version of the Social Communication Questionnaire (K-SCQ) was used to evaluate symptoms of ASD. The Wilcoxon signed-rank test was used to compare the differences before and after Theraplay.
Results:
Upon comparing the differences in total K-SCQ scores, there were statistically significant changes (z=-3.269, p=0.001) in children with ASD. Changes were also confirmed in each category, namely social interaction, communication, and limited and repetitive behavior patterns (p=0.011, p=0.025, p=0.039, respectively).
Conclusion
This study found that Theraplay may cause significant changes in social communication in children with ASD. Further studies are needed to establish the effectiveness of Theraplay in children with ASD.
7.A Brief Replication Study Comparing Stimulants and Non-Stimulants for Attention-Deficit/Hyperactivity Disorder Treatment with a Focus on the Compliance, Efficacy, and Satisfaction
Journal of the Korean Academy of Child and Adolescent Psychiatry 2021;32(1):10-16
Objectives:
The aim of this study was to compare the compliance, efficacy, and satisfaction associated with methylphenidate and atomoxetine for treating attention-deficit/hyperactivity disorder (ADHD).
Methods:
The subjects were 44 patients who met the Diagnostic and Statistical Manual of Mental Disorder-5 diagnostic criteria for ADHD and were treated with methylphenidate or atomoxetine. The methylphenidate formulations included immediate release (IR), extended release (ER), and osmotic-controlled release oral delivery system (OROS). Patients and parents reported the average number of days per week the medication was taken. Efficacy was assessed using the ADHD Rating Scale. Satisfaction with medication scale (SAMS)–parent report form and SAMS–self-report form were used to evaluate parents’ and patients’ satisfaction, respectively.
Results:
Patients and parents were more satisfied with methylphenidate than with atomoxetine. There were no significant differences in the compliance with and efficacy of methylphenidate and atomoxetine. Compliance with methylphenidate IR and ER was markedly lower than that with OROS methylphenidate or atomoxetine.
Conclusion
Methylphenidate OROS formulation can be considered a suitable option given its high rates of compliance, satisfaction, and efficacy.
8.Development of the Korean Practice Parameter for Adult Attention-Deficit/Hyperactivity Disorder
Geon Ho BAHN ; Young Sik LEE ; Hanik K. YOO ; Eui-Jung KIM ; Subin PARK ; Doug Hyun HAN ; Minha HONG ; Bongseog KIM ; Soyoung Irene LEE ; Soo Young BHANG ; Seung Yup LEE ; Jin Pyo HONG ; Yoo-Sook JOUNG
Journal of the Korean Academy of Child and Adolescent Psychiatry 2020;31(1):5-25
Objectives:
Adult attention-deficit/hyperactivity disorder (ADHD) is an important mental health problem that needs resolution, especially considering the high rates of ADHD continuation from childhood to adolescence/adulthood and the high prevalence of ADHD in adults. Adults with ADHD have lifelong negative impacts and require close monitoring with long-term follow-up. Hence, the establishment of a Korean practice parameter for adult ADHD is necessary to minimize discontinuation of treatment and enable information sharing among Korean mental health professionals.
Methods:
The Korean practice parameter was developed using an evidence-based approach consisting of expert consensus survey coupled with literature review.
Results:
According to the expert consensus survey, the most commonly used diagnostic methods were clinical psychiatric interview (20.66%) and self-report scales (19.25%) followed by attention (14.71%) and psychological tests (14.24%). Key evaluation instruments currently available in Korea are the World Health Organization Adult ADHD Self-Report Rating Scale, Korean Adult ADHD Rating Scale, Diagnostic Interview for ADHD in Adults, Barkley Deficits in Executive Functioning Scale for adults, Comprehensive Attention Test, Conners’ Continuous Performance Test, and the subtests of Wechsler Adult Intelligence Scale, Digit Span and Letter-Number Sequencing. Although pharmacotherapy is recommended as the first-line of treatment for adult ADHD, we recommend that it be followed by a multimodal and multidisciplinary approach including psychoeducation, pharmacotherapy, cognitive behavior therapy and coaching.
Conclusion
The Korean practice parameter introduces not only general information for the diagnosis and treatment of adult ADHD on a global scale, but also the process of diagnosis and treatment options tailored to the Korean population.
9.Development of the Korean Practice Parameter for Adult Attention-Deficit/Hyperactivity Disorder
Geon Ho BAHN ; Young Sik LEE ; Hanik K. YOO ; Eui-Jung KIM ; Subin PARK ; Doug Hyun HAN ; Minha HONG ; Bongseog KIM ; Soyoung Irene LEE ; Soo Young BHANG ; Seung Yup LEE ; Jin Pyo HONG ; Yoo-Sook JOUNG
Journal of the Korean Academy of Child and Adolescent Psychiatry 2020;31(1):5-25
Objectives:
Adult attention-deficit/hyperactivity disorder (ADHD) is an important mental health problem that needs resolution, especially considering the high rates of ADHD continuation from childhood to adolescence/adulthood and the high prevalence of ADHD in adults. Adults with ADHD have lifelong negative impacts and require close monitoring with long-term follow-up. Hence, the establishment of a Korean practice parameter for adult ADHD is necessary to minimize discontinuation of treatment and enable information sharing among Korean mental health professionals.
Methods:
The Korean practice parameter was developed using an evidence-based approach consisting of expert consensus survey coupled with literature review.
Results:
According to the expert consensus survey, the most commonly used diagnostic methods were clinical psychiatric interview (20.66%) and self-report scales (19.25%) followed by attention (14.71%) and psychological tests (14.24%). Key evaluation instruments currently available in Korea are the World Health Organization Adult ADHD Self-Report Rating Scale, Korean Adult ADHD Rating Scale, Diagnostic Interview for ADHD in Adults, Barkley Deficits in Executive Functioning Scale for adults, Comprehensive Attention Test, Conners’ Continuous Performance Test, and the subtests of Wechsler Adult Intelligence Scale, Digit Span and Letter-Number Sequencing. Although pharmacotherapy is recommended as the first-line of treatment for adult ADHD, we recommend that it be followed by a multimodal and multidisciplinary approach including psychoeducation, pharmacotherapy, cognitive behavior therapy and coaching.
Conclusion
The Korean practice parameter introduces not only general information for the diagnosis and treatment of adult ADHD on a global scale, but also the process of diagnosis and treatment options tailored to the Korean population.
10.Comparison of Attention-Deficit/Hyperactivity Disorder Practice in Adults According to a Training Background in Child Psychiatry
Minha HONG ; Seung Yup LEE ; Young Sik LEE ; Bongseog KIM ; Yoo Sook JOUNG ; Hanik K YOO ; Eui Jung KIM ; Soyoung Irene LEE ; Su Bin PARK ; Soo Young BHANG ; Doughyun HAN ; Geon Ho BAHN
Journal of the Korean Academy of Child and Adolescent Psychiatry 2019;30(3):121-126
OBJECTIVES: Awareness of attention-deficit/hyperactivity disorder (ADHD) in adults has significantly increased; however, clinical data specific to the Korean population are insufficient. Clinical experience of ADHD may differ based on whether psychiatrists have received pediatric psychiatry-specific training. In order to prepare a practice parameter for adult ADHD patients in Korea, we examined questionnaire data to observe how pediatric psychiatry training could affect clinical practice for adults with ADHD. METHODS: A questionnaire about the diagnosis and treatment process was distributed to both general psychiatrists (GPsy) and child and adolescent psychiatrists (CAP) at the summer and winter workshop meetings of Korean Academy of Child and Adolescent Psychiatry. RESULTS: In total, 142 psychiatrists participated in the survey (86 GPsy, 56 CAP). GPsy and CAP preferred pharmacotherapy (GPsy 82.40%, CAP 64.30%) as the primary treatment option and answered that the clinical psychiatric interview is the most necessary step in diagnostic assessment (GPsy 22.16%, CAP 19.00%). The GPsy responded with an optimal and average treatment duration that was shorter than that reported by CAP. CONCLUSION: Identification of the initial presenting symptom as the correct diagnosis and the optimal duration of pharmacotherapy differed between GPsy and CAP in practice, whereas concepts in diagnosis and treatment of ADHD in adults were similar for both groups. These results suggest the urgent need for the Continuing Medical Education program for psychiatrists treating adults with ADHD.
Adolescent
;
Adolescent Psychiatry
;
Adult
;
Attention Deficit Disorder with Hyperactivity
;
Child
;
Child Psychiatry
;
Child
;
Diagnosis
;
Drug Therapy
;
Education
;
Education, Medical, Continuing
;
Humans
;
Korea
;
Psychiatry

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