1.2023 Clinical Practice Guidelines for Diabetes Management in Korea: Full Version Recommendation of the Korean Diabetes Association
Jun Sung MOON ; Shinae KANG ; Jong Han CHOI ; Kyung Ae LEE ; Joon Ho MOON ; Suk CHON ; Dae Jung KIM ; Hyun Jin KIM ; Ji A SEO ; Mee Kyoung KIM ; Jeong Hyun LIM ; Yoon Ju SONG ; Ye Seul YANG ; Jae Hyeon KIM ; You-Bin LEE ; Junghyun NOH ; Kyu Yeon HUR ; Jong Suk PARK ; Sang Youl RHEE ; Hae Jin KIM ; Hyun Min KIM ; Jung Hae KO ; Nam Hoon KIM ; Chong Hwa KIM ; Jeeyun AHN ; Tae Jung OH ; Soo-Kyung KIM ; Jaehyun KIM ; Eugene HAN ; Sang-Man JIN ; Jaehyun BAE ; Eonju JEON ; Ji Min KIM ; Seon Mee KANG ; Jung Hwan PARK ; Jae-Seung YUN ; Bong-Soo CHA ; Min Kyong MOON ; Byung-Wan LEE
Diabetes & Metabolism Journal 2024;48(4):546-708
2.Angiographic Insights and Endovascular Intervention in Pulmonary Artery Pseudoaneurysms:A Comprehensive Clinical and Pictorial Essay
Min Jeong CHOI ; Bong Man KIM ; Sang Yoon KIM ; You Me KIM
Journal of the Korean Society of Radiology 2024;85(6):1083-1096
Pulmonary artery pseudoaneurysms (PAPs) are rare and can occasionally be overlooked as a cause of hemoptysis. The rupture of PAPs may lead to severe and massive hemoptysis and asphyxiation, necessitating prompt and accurate diagnostic measures, including CT angiography, in conjunction with clinical awareness for adequate management. The aim of this pictorial essay is to establish a strategy for endovascular intervention based on a comprehensive understanding of the etiology and hemodynamics of bronchopulmonary circulation for effective and rapid PAP treatment.
3.Angiographic Insights and Endovascular Intervention in Pulmonary Artery Pseudoaneurysms:A Comprehensive Clinical and Pictorial Essay
Min Jeong CHOI ; Bong Man KIM ; Sang Yoon KIM ; You Me KIM
Journal of the Korean Society of Radiology 2024;85(6):1083-1096
Pulmonary artery pseudoaneurysms (PAPs) are rare and can occasionally be overlooked as a cause of hemoptysis. The rupture of PAPs may lead to severe and massive hemoptysis and asphyxiation, necessitating prompt and accurate diagnostic measures, including CT angiography, in conjunction with clinical awareness for adequate management. The aim of this pictorial essay is to establish a strategy for endovascular intervention based on a comprehensive understanding of the etiology and hemodynamics of bronchopulmonary circulation for effective and rapid PAP treatment.
4.Angiographic Insights and Endovascular Intervention in Pulmonary Artery Pseudoaneurysms:A Comprehensive Clinical and Pictorial Essay
Min Jeong CHOI ; Bong Man KIM ; Sang Yoon KIM ; You Me KIM
Journal of the Korean Society of Radiology 2024;85(6):1083-1096
Pulmonary artery pseudoaneurysms (PAPs) are rare and can occasionally be overlooked as a cause of hemoptysis. The rupture of PAPs may lead to severe and massive hemoptysis and asphyxiation, necessitating prompt and accurate diagnostic measures, including CT angiography, in conjunction with clinical awareness for adequate management. The aim of this pictorial essay is to establish a strategy for endovascular intervention based on a comprehensive understanding of the etiology and hemodynamics of bronchopulmonary circulation for effective and rapid PAP treatment.
5.Varied strategies for alcohol-related liver transplants in South Korea
Hyun Hwa CHOI ; Kwang-Woong LEE ; Bong-Wan KIM ; Dong-Sik KIM ; Gyu-Seong CHOI ; Hae Won LEE ; Ho Joong CHOI ; Jaryung HAN ; Je Ho RYU ; Kwan Woo KIM ; Man Ki JU ; Min-Su PARK ; Myoung Soo KIM ; Seok-Hwan KIM ; Seoung Hoon KIM ; Shin HWANG ; Sung Won JUNG ; Tae-Seok KIM ; Woo Young SHIN
Annals of Liver Transplantation 2024;4(2):95-101
Background:
s: Alcohol-related liver disease (ALD) is currently a major indication for liver transplantation (LT) in South Korea. Alcoholic recidivism is a primary concern after LT for ALD. However, it is unclear how patients who have received LT for ALD are managed regarding medical and psychological issues. Furthermore, management approaches vary across centers. This study aims to investigate how these management approaches differ among centers.
Methods:
We conducted a survey of 19 liver transplant centers in South Korea to gather detailed information on the management protocols and related issues of ALD in LT patients.
Results:
All 19 centers that responded to the survey had been performing LT for patients with ALD for more than 5 years. Nine out of the 19 centers (47%) stated that a minimum abstinence period of 1–6 months from alcohol was required before evaluating LT and enrolling on the transplant waiting list. Only 2 (10%) and 5 (26%) centers had protocols for assessing alcohol consumption while awaiting LT or for treating alcohol consumption after transplantation, respectively. Monitoring abstinence from drinking before and after LT mostly relied on direct interviews, and alcohol biomarkers were not used.
Conclusion
Our findings emphasize the importance of consistent patient management guidelines for ALD-LTs in South Korea.
6.Prevalence of Loneliness and Its Association With Suicidality in the General Population: Results From a Nationwide Survey in Korea
Jimin LEE ; Sung Man CHANG ; Bong-Jin HAHM ; Jee Eun PARK ; Su Jeong SEONG ; Jin Pyo HONG ; Hong Jin JEON ; Hyonggin AN ; Byung-Soo KIM
Journal of Korean Medical Science 2023;38(36):e287-
Background:
Although it is known that a substantial proportion of the population experience loneliness, the consequence of loneliness remains unclear by countries and ages.Accordingly, this study aimed to assess the association between loneliness and suicidality in the general population of Korea.Method: A total of 5,511 Koreans aged 18–79 completed a tablet-assisted personal interview using the Korean version of the Composite International Diagnostic Interview and responded to questions about loneliness and lifetime suicidal ideation, plans, and attempts. A logistic regression analysis was used to examine the association between loneliness and suicidality.
Results:
Approximately one-third of the Korean general population reported loneliness.Being older, never married, widowed, separated, or divorced, unemployed, and having a parttime job were all significantly related to loneliness. After adjusting for sociodemographic factors, individuals with loneliness were significantly associated with increased suicidal ideation (adjusted odd ratio [aOR], 4.05; 95% confidence interval [CI], 3.36–4.88), suicidal plans (aOR, 4.91; 95% CI, 3.34–7.21), and suicidal attempts (aOR, 4.82; 95% CI, 3.03–7.66). Even after adjusting for sociodemographic factors and mental disorders, suicidality remained statistically significant. Moreover, frequent, moderate-to-severe, and long-term loneliness were all associated with increased ORs for suicidality, regardless of sociodemographic factors and mental disorders.
Conclusion
Loneliness was associated with suicidal ideation, plans, and attempts. This study lays the foundation for public health policymakers to establish early intervention and mental health care support for lonely people.
7.Validation of the Patient Health Questionnaire–9 and Patient Health Questionnaire–2 in the General Korean Population
Minah KIM ; Sanghyup JUNG ; Jee Eun PARK ; Jee Hoon SOHN ; Su Jeong SEONG ; Byung-Soo KIM ; Sung Man CHANG ; Jin Pyo HONG ; Bong-Jin HAHM ; Chan-Woo YEOM
Psychiatry Investigation 2023;20(9):853-860
Objective:
The Patient Health Questionnaire–9 (PHQ-9) and PHQ-2 have not been validated in the general Korean population. This study aimed to validate and identify the optimal cutoff scores of the PHQ-9 and PHQ-2 in screening for major depression in the general Korean population.
Methods:
We used data from 6,022 participants of the Korean Epidemiological Catchment Area Study for Psychiatric Disorders in 2011. Major depression was diagnosed according to the Korean Composite International Diagnostic Interview. Validity, reliability, and receiver operating characteristic curve analyses were performed using the results of the PHQ-9 and Euro Quality of life-5 dimension (EQ-5d).
Results:
Of the 6,022 participants, 150 were diagnosed with major depression (2.5%). Both PHQ-9 and PHQ-2 demonstrated relatively high reliability and their scores were highly correlated with the “anxiety/depression” score of the EQ-5d. The optimal cutoff score of the PHQ-9 was 5, with a sensitivity of 89.9%, specificity of 84.1%, positive predictive value (PPV) of 12.6%, negative predictive value (NPV) of 99.7%, positive likelihood ratio (LR+) of 5.6, and negative likelihood ratio (LR-) of 0.12. The optimal cutoff score of the PHQ-2 was 2, with a sensitivity of 85.3%, specificity of 83.2%, PPV of 11.6%, NPV of 99.5%, LR+ of 5.1, and LR- of 0.18.
Conclusion
The PHQ-9 and PHQ-2 are valid tools for screening major depression in the general Korean population, with suggested cutoff values of 5 and 2 points, respectively.
8.Insulin Fact Sheet in Type 1 and 2 Diabetes Mellitus and Trends of Antidiabetic Medication Use in Insulin Users with Type 2 Diabetes Mellitus: 2002 to 2019
Jiyun PARK ; Gyuri KIM ; Bong-Sung KIM ; Kyung-Do HAN ; So Yoon KWON ; So Hee PARK ; You-Bin LEE ; Sang-Man JIN ; Jae Hyeon KIM
Diabetes & Metabolism Journal 2023;47(2):211-219
Background:
This study investigated the trends of insulin use among Korean patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). Changes in prescription of antidiabetic medications in T2DM patients taking insulin therapy were evaluated.
Methods:
We analyzed data from the National Health Insurance Service database in Korea to evaluate the prevalence of insulin users and trends of insulin use in T1DM and T2DM patients from January 2002 to December 2019. We also investigated numbers and types of antidiabetic medications in insulin users with T2DM.
Results:
The overall total number of insulin users increased from 2002 to 2019, reaching 348,254 for T2DM and 20,287 for T1DM in 2019 compared with 109,974 for T2DM and 34,972 for T1DM in 2002. The proportion of patients using basal analogs and short acting analogs have increased and those using human insulin, premixed insulin, or biphasic human insulin have decreased (rapid acting analogs: 71.85% and 24.12% in T1DM and T2DM, respectively, in 2019; basal analogs: 76.75% and 75.09% in T1DM and T2DM, respectively, in 2019). The use of other antidiabetic medication in addition to insulin increased for T2DM, especially in dual therapy, reaching up to 52.35% in 2019 compared with 16.72% in 2002.
Conclusion
The proportion of the patients using basal or rapid acting analogs increased among all insulin users in both T1DM and T2DM patients. Among patients with T2DM, the proportion of patients using antidiabetic medications in addition to insulin was significantly increased compared to those who used insulin alone.
9.Prevalence of Mental Disorders and Associated Factors in Korean Adults: National Mental Health Survey of Korea 2021
Soo Jung RIM ; Bong-Jin HAHM ; Su Jeong SEONG ; Jee Eun PARK ; Sung Man CHANG ; Byung-Soo KIM ; Hyonggin AN ; Hong Jin JEON ; Jin Pyo HONG ; Subin PARK
Psychiatry Investigation 2023;20(3):262-272
Objective:
Mental health is a global concern and needs to be studied more closely. We aimed to estimate the prevalence of mental disorders and their associated factors among the general population in Korea.
Methods:
The National Mental Health Survey of Korea 2021 was conducted between June 19 and August 31, 2021 and included 13,530 households; 5,511 participants completed the interview (response rate: 40.7%). The lifetime and 12-month diagnosis rates of mental disorders were made using the Korean version of the Composite International Diagnostic Interview 2.1. Factors associated with alcohol use disorder (AUD), nicotine use disorder, depressive disorder, and anxiety disorder were analyzed, and mental health service utilization rates were estimated.
Results:
The lifetime prevalence of mental disorders was 27.8%. The 12-month prevalence rates of alcohol use, nicotine use, depressive, and anxiety disorders were 2.6%, 2.7%, 1.7%, and 3.1%, respectively. The risk factors associated with 12-month diagnosis rates were as follows: AUD: sex and age; nicotine use disorder: sex; depressive disorder: marital status and job status; anxiety disorder: sex, marital status, and job status. The 12-month treatment and service utilization rates for 12-month AUD, nicotine use disorder, depressive disorder, and anxiety disorder were 2.6%, 1.1%, 28.2%, and 9.1%, respectively.
Conclusion
Approximately 25% of adults in the general population were diagnosed with mental disorders during their lifetime. The treatment rates were substantially low. Future studies on this topic and efforts to increase the mental health treatment rate at a national level are needed.
10.Delayed Chylothorax Following Blunt Chest Trauma Treated with Repeated Lymphangiography: A Case Presentation
Gayoung KIM ; Dongsub NOH ; Bong Man KIM ; Yoonjung HEO
Journal of Acute Care Surgery 2023;13(1):39-42
Chylothorax is mostly iatrogenic, with blunt chest trauma being a rare cause. Treatment depends on the volume of drainage. Specifically, conservative treatment, such as total parenteral nutrition and pleural drainage, is performed in cases of low daily output (< 500 mL/day). Patients with persistent chylothorax despite medical treatment or with high daily output (> 1-1.5 L/day) are candidates for surgical or radiological intervention. We present a case of delayed-onset chylothorax after blunt trauma caused by thoracic spine fractures, in which persistent chylothorax was successfully managed with repeated lymphangiography with lipiodol when other treatment modalities failed. The case is peculiar in that the chylothorax occurred 40 days after the initial traumatic event and was treated with lipiodol injection, despite maintaining moderate to high daily output.

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