1.Study on the effect of Bian-stone-based herbal heat therapy on gastrointestinal reactions during the precon-ditioning period of hematopoietic stem cell transplantation patients
Binlian YAO ; Min XU ; Xiaopei MAO ; Min PENG ; Rui ZHU ; Xiaolan ZHANG ; Menghua YE ; Danhua YANG
Chinese Journal of Nursing 2025;60(12):1420-1426
Objective Exploring the effect of Bian-stone-based herbal heat therapy on herbal heat ironing in gastrointestinal reactions during the preconditioning period of hematopoietic stem cell transplantation patients.Methods Convenience sampling method was used to select 68 cases of hematopoietic stem cell transplantation patients who attended the hematology department of a tertiary-level Chinese medicine hospital in Hangzhou from October 2023 to April 2024 as the study subjects,and the SPSS 26.0 statistical software was used to generate a random number for grouping into an experimental and a control group,with 34 cases in each group.On the basis of intravenous antiemetic medication and routine,the experimental group implemented the Bian-stone-based herbal heat therapy on the basis of intravenous antiemetic medication and conventional nursing care.In the control group,intravenous antiemetic drugs and routine care were used,and the intervention duration of both groups was 14 d,of which 7 d was a course of treatment,with a total of 2 courses of treatment.The incidence of gastroin-testinal reactions,Gastrointestinal Symptom Rating Scale(GSRS)score,Pepsin Ⅰ(PG Ⅰ),Pepsin Ⅱ(PG Ⅱ),and the ratio of PG Ⅰ to PG Ⅱ(PGR)before and after the intervention were compared between the 2 groups.Results The final sample of 66 cases was collected in this study,and 1 patient was dislodged from each of the control group and the experimental group.The comparison of the incidence of gastrointestinal reactions between the 2 groups within 14 days showed that the incidences of nausea,vomiting,abdominal distension,and diarrhea were lower in the experimental group than those in the control group(P<0.05).GSRS scores on days 1,8,and 14 of intervention were compared,and there were effects between groups in both groups(F=5.338,P=0.017).The levels of PG Ⅰ,PG Ⅱ in the experimental group on day 8 of the intervention were lower than those in the control group.The levels of PGR was higher than that in the control group(all P<0.05).The safety of the 2 groups after treatment was evaluated,and the results showed that no serious adverse events occurred in the 2 groups.Conclusion Bian-stone-based herbal heat therapy can improve gastrointestinal reactions and reduce the incidence of gastrointestinal reactions during the preconditioning period of hematopoietic stem cell transplantation patients,which provides clinical guidance for the application of Bian-stone-based herbal heat therapy by nursing staff in the future.
2.Study on the effect of Bian-stone-based herbal heat therapy on gastrointestinal reactions during the precon-ditioning period of hematopoietic stem cell transplantation patients
Binlian YAO ; Min XU ; Xiaopei MAO ; Min PENG ; Rui ZHU ; Xiaolan ZHANG ; Menghua YE ; Danhua YANG
Chinese Journal of Nursing 2025;60(12):1420-1426
Objective Exploring the effect of Bian-stone-based herbal heat therapy on herbal heat ironing in gastrointestinal reactions during the preconditioning period of hematopoietic stem cell transplantation patients.Methods Convenience sampling method was used to select 68 cases of hematopoietic stem cell transplantation patients who attended the hematology department of a tertiary-level Chinese medicine hospital in Hangzhou from October 2023 to April 2024 as the study subjects,and the SPSS 26.0 statistical software was used to generate a random number for grouping into an experimental and a control group,with 34 cases in each group.On the basis of intravenous antiemetic medication and routine,the experimental group implemented the Bian-stone-based herbal heat therapy on the basis of intravenous antiemetic medication and conventional nursing care.In the control group,intravenous antiemetic drugs and routine care were used,and the intervention duration of both groups was 14 d,of which 7 d was a course of treatment,with a total of 2 courses of treatment.The incidence of gastroin-testinal reactions,Gastrointestinal Symptom Rating Scale(GSRS)score,Pepsin Ⅰ(PG Ⅰ),Pepsin Ⅱ(PG Ⅱ),and the ratio of PG Ⅰ to PG Ⅱ(PGR)before and after the intervention were compared between the 2 groups.Results The final sample of 66 cases was collected in this study,and 1 patient was dislodged from each of the control group and the experimental group.The comparison of the incidence of gastrointestinal reactions between the 2 groups within 14 days showed that the incidences of nausea,vomiting,abdominal distension,and diarrhea were lower in the experimental group than those in the control group(P<0.05).GSRS scores on days 1,8,and 14 of intervention were compared,and there were effects between groups in both groups(F=5.338,P=0.017).The levels of PG Ⅰ,PG Ⅱ in the experimental group on day 8 of the intervention were lower than those in the control group.The levels of PGR was higher than that in the control group(all P<0.05).The safety of the 2 groups after treatment was evaluated,and the results showed that no serious adverse events occurred in the 2 groups.Conclusion Bian-stone-based herbal heat therapy can improve gastrointestinal reactions and reduce the incidence of gastrointestinal reactions during the preconditioning period of hematopoietic stem cell transplantation patients,which provides clinical guidance for the application of Bian-stone-based herbal heat therapy by nursing staff in the future.
3.Construction and application of"Internet+TCM nursing service"talent cultivation model in Zhejiang Province
Binlian YAO ; Min XU ; Menghua YE ; Xiaojie CHEN ; Fuying YE ; Yongjian WANG ; Juanying LIN ; Feilin NI ; Xiaolan ZHANG
Chinese Journal of Nursing 2024;59(8):980-986
Objective To construct an"Internet+TCM nursing service"talent cultivation model in Zhejiang Province and to evaluate its application effect.Methods Based on the literature review and expert panels,the"Internet+TCM nursing service"talent cultivation model was constructed in Zhejiang Province.A total of 63 trainees from 63 TCM and integrated traditional Chinese and Western medicine hospitals in the province were selected to carry out for 45 days of theoretical training and 9 days of clinical skills training.After the training,the training effect was evaluated by theoretical knowledge,TCM nursing skills,scenario simulation case assessment,trainees'satisfaction,as well as a survey on the results of practice.Results The constructed talent cultivation model contains course contents including theoretical learning,skill training and emergency home treatment management and corresponding assessment programs.Sixty-three trainees successfully completed the course with the theoretical score of(92.24±3.64),the skill score of(97.13±2.53),and the situational case score of(95.78±3.02).Fifty-five trainees(87.30%)were assessed as"excellent"and 8(12.70%)as"good".The trainees'satisfaction about the overall module design of the project was(4.93±0.23)and 415 cases of"Internet+TCM nursing service"were carried out.Conclusion The"Internet+TCM nursing service"talent cultivation model in Zhejiang Province has strong applicability and remarkable training effect,which can provide references for the implementation of"Internet+TCM nursing service"in other regions.
4.Effect of compound matrine oxygen inhalation on prevention of oral mucosal inflammation for patients after hemopoietic stem cells transplantation
Binlian YAO ; Jieying ZHOU ; Wangfang SHEN ; Shuifen WU ; Guan WANG ; Yuhong ZHOU
Chinese Journal of Modern Nursing 2016;22(1):66-69
Objective To explore the effects of compound matrine oxygen inhalation on prevention of oral mucosal inflammation for patients after hemopoietic stem cells transplantation. Methods A total of 60 patients with allogeneic hemopoietic stem cells transplantation were divided into observation group (30 cases, routine oral nursing and compound matrine oxygen inhalation ) and control group ( 30 cases, routine oral nursing) by random number table. We observed the degree of oral mucosal inflammation and counted the position in two groups during pre-treatment period, low cell stage and convalescence stage from one day before pre-treatment period to 29 days after transplantation. Results The incidences of oral mucosal inflammation were 10. 0%, 56. 7%, 33. 3% in the observation group and 40. 0%, 100. 0%, 93. 3% in the control group during pretreatment period, low cell stage and convalescence stage (Z=3. 406, 5. 720, 5. 002;P<0. 05). There were significant differences in the numbers of occurrence sites between the two groups during pre-treatment period, low cell stage and convalescence stage (Z =2. 866, 6. 596, 5. 448;P <0. 05). Conclusions Compound matrine oxygen inhalation can decrease the degree of oral mucosal inflammation and reduce the occurrence sites of oral mucosal inflammation.

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