1.Functional mechanisms of CIPKs in plant responses to biotic and abiotic stresses.
Bingzi YANG ; Guoqiang WU ; Ming WEI ; Bin CHENG
Chinese Journal of Biotechnology 2025;41(7):2596-2609
Calcineurin B-like protein (CBL)-interacting protein kinases (CIPKs) are a group of Ser/Thr protein kinases, playing a crucial role in the growth, development, and stress responses of plants. CIPKs can undergo autophosphorylation or target the phosphorylation of other signaling factors in responses to biotic and abiotic stresses. In addition, they are involved in the signaling pathways of plant hormones such as abscisic acid (ABA), gibberellic acid (GA), ethylene (ETH), and salicylic acid (SA) to regulate plant growth and development. Furthermore, CIPKs respond to stresses such as salinity, drought, cold, and heavy metals by forming complexes through specific interactions with CBLs. In this study, we summarized the discovery, structures, classification, regulatory mechanisms, and roles of CIPKs in plant responses to stresses and made an outlook on the future research directions. This review is expected to provide genetic resources and theoretical foundations for the genetic improvement and breeding of crops with stress tolerance.
Stress, Physiological/physiology*
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Protein Serine-Threonine Kinases/genetics*
;
Signal Transduction/physiology*
;
Plant Growth Regulators/metabolism*
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Plant Proteins/genetics*
;
Plants/metabolism*
2.Research progress of health science popularization in the treatment of differentiated thyroid carcinoma with 131I
Yan WANG ; Bingzi SHI ; Suyun YANG
Chinese Journal of Modern Nursing 2023;29(30):4190-4195
Health science popularization is one of the key factors for patients with differentiated thyroid carcinoma treated with 131I to achieve positive survival outcomes. This paper reviews the general situation of health science popularization, the necessity of health science popularization for differentiated thyroid carcinoma treated with 131I and the current implementation situation at home and abroad, in order to provide reference for comprehensive health science popularization for differentiated thyroid carcinoma treated with 131I in clinical practice.
3.Research progress on radiation safety guidance for thyroid cancer patients treated with 131I
Chinese Journal of Modern Nursing 2022;28(25):3508-3512
Radioactive iodine therapy is a safe and effective postoperative treatment for patients with differentiated thyroid cancer. Since 131I is a radionuclide, the patient becomes a living radioactive source after receiving 131I treatment, causing radioactive damage to the surrounding population and the environment. This article reviews the necessity of radiation safety guidance for differentiated thyroid cancer patients undergoing 131I treatment and the content of radiation safety guidance during hospitalization and after discharge, aiming to provide reasonable guidance on radiation safety for these patients. It provides a reference for the formulation of radiation safety management plans in line with national conditions in the future.

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