Wound healing is a significant medical challenge,particularly in the treatment of chronic wounds.Traditional therapeutic methods often fall short in addressing the complex demands of chronic wounds,such as diabetic foot ulcers and deep burns.Recently,the combination of hydrogels and stem cell technology has offered new hope for wound treatment.Hydrogels,with their excellent moisturizing properties,breathability,and biocompatibility,have become ideal materials for wound coverage.Stem cells,renowned for their regenerative and tissue repair capabilities,are highly valued in this context.Hydrogels provide a three-dimensional scaffold that mimics the wound site's natural environment,promoting the adhesion,growth,and differentiation of stem cells.They can also be engineered as delivery systems to release growth factors or drugs in a controlled manner,directly targeting the treatment area and accelerating the healing process.Meanwhile,stem cells enhance the repair functions of surrounding tissues by secreting growth factors and cytokines,improving local blood circulation,and reducing inflammation.This article reviews the development and application of hydrogels combined with stem cells in promoting wound healing,in order to provide new ideas and strategies for the clinical treatment of chronic wounds.

Wound healing is a significant medical challenge,particularly in the treatment of chronic wounds.Traditional therapeutic methods often fall short in addressing the complex demands of chronic wounds,such as diabetic foot ulcers and deep burns.Recently,the combination of hydrogels and stem cell technology has offered new hope for wound treatment.Hydrogels,with their excellent moisturizing properties,breathability,and biocompatibility,have become ideal materials for wound coverage.Stem cells,renowned for their regenerative and tissue repair capabilities,are highly valued in this context.Hydrogels provide a three-dimensional scaffold that mimics the wound site's natural environment,promoting the adhesion,growth,and differentiation of stem cells.They can also be engineered as delivery systems to release growth factors or drugs in a controlled manner,directly targeting the treatment area and accelerating the healing process.Meanwhile,stem cells enhance the repair functions of surrounding tissues by secreting growth factors and cytokines,improving local blood circulation,and reducing inflammation.This article reviews the development and application of hydrogels combined with stem cells in promoting wound healing,in order to provide new ideas and strategies for the clinical treatment of chronic wounds.

Objective To scale the frequencise of medical X-ray diagnosis based on the survey conducted in 58 hospitals to the all hospitals in Henan province,in order to make them available for providing the basis for reasonable application of diagnostic radiology.Methods Stratified sampling method was used to select medical institutions at different levels in 6 cities in the province as sample hospitals.The information of examined patients on sex,age,diagnostic type and exposure category were gathered and the results were analyzed.Results The sex ratio of male and female examined patients was close to 1∶1.The largest proportion,60.47％,of examined patients was from the age group of above 40 years old among the three age groups.Medical diagnositc medical X-ray examinations mainly include conventional X-ray photography and CT examination,accounting for 52.15％ and 40.31％,respectively.Chest examination contributed the largest propotions,23.84％,of conventional diagnositic X-ray examination and,13.25％,of CT examination respectively.CT examinations were mainly concentrated in the secondary and tertiary hospitals,accounting for 21.54％ and 72.99％ of the total CT examinations,respectively.Contrast examination,mammography and extracorporeal lithotripsy were concentrated in the tertiary hospitals,accounting for 77.82％,95.01％ and 100％ of the same type of examinations,respectively.Conventional photographic examinations were mainly conducted in primary hospitals,accounting for 74.56％ of all types of examinations in the primary hospitals.By using multiple linear regression model,the diagnostic examination frequency in 2016 was estimated to be 826 examinations per 1 000 population,of which the frequency of dianostic X-ray examination and CT examination were 541 per 1 000 and 285 per 1 000,respectively.Conclusions The frequency of diagnostic radiology in Henan has increased rapidly in recent years.All types of diagnostic radiology equipment are unevenly distributed in hospitals at different levels which posed a challenge for health care.Relevant departments should make efforts to reallocation of diagnostic radiology equipment in such hospitals and make utilization of health resources more reasonable.