1.Predicting late aortic complications after acute type A dissection surgery with volumetric measurements in a Singapore cohort.
Jasmine GE ; Vinay Bahadur PANDAY ; Siew-Pang CHAN ; Bernard WEE ; Julian Chi Leung WONG ; Leok Kheng Kristine TEOH ; Moe Thu SAN ; Carlos A MESTRES ; Theodoros KOFIDIS ; Vitaly A SOROKIN
Singapore medical journal 2025;66(9):469-475
INTRODUCTION:
This study was conducted to evaluate the efficacy of postoperative computed tomography (CT) measurements of aortic lumen volumes in predicting aortic-related complications following acute type A aortic dissection (ATAAD) repair.
METHODS:
We conducted a single-institution retrospective aortic volumetric analysis of patients after ascending aorta replacement performed during 2001-2015. The volumetric measurements of total lumen (total-L), true lumen (TL), false lumen (FL), as well as the TL:FL ratio from the first and second postoperative computer angiograms were obtained. A generalised structural equation model was created to analyse the predictive utility of TL:FL ratio.
RESULTS:
One hundred and twenty-five patients underwent surgical intervention, of whom 97 patients were eventually discharged and analysed for postoperative complications. A total of 19 patients were included in the final analysis. Patients with late postoperative aortic complications had a significantly higher FL volume and total-L volume on the first (FL volume P = 0.041, total-L volume P = 0.05) and second (FL volume P = 0.01, total-L volume P = 0.007) postoperative scans. The odds of having aortic complications were raised by 1% with a 1 cm 3 increase in total-L volume and by 2% with a 1 cm 3 increase in FL volume. The TL:FL ratio was significantly lower in patients who developed complications.
CONCLUSION
Postoperative CT volumetric measurements in patients who developed complications are characterised by a significant increase in the FL volume and total-L volume from the first postoperative scans. Patients with disproportionately expanded FL presenting with TL:FL ratios less than 1 were associated with aortic complications. Hence, the TL:FL ratio may be a reliable and useful parameter to monitor postoperative disease progression and to evaluate the risk of late complications in ATAAD patients.
Humans
;
Male
;
Female
;
Retrospective Studies
;
Singapore
;
Aortic Dissection/diagnostic imaging*
;
Middle Aged
;
Postoperative Complications/diagnostic imaging*
;
Aged
;
Tomography, X-Ray Computed
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Aortic Aneurysm/diagnostic imaging*
;
Aorta/surgery*
;
Adult
;
Treatment Outcome
;
Computed Tomography Angiography
2.Struma ovarii: management and follow-up of a rare ovarian tumour.
Jonathan Yeow Sherng WEE ; Xinyi LI ; Bernard Su Min CHERN ; Irene Sze Yuen CHUA
Singapore medical journal 2015;56(1):35-39
INTRODUCTIONStruma ovarii represents about 1.0% of all ovarian tumours. While management involves surgery, there is a paucity of data regarding the extent and approach of surgery, and postoperative management. This study aimed to delineate the management of struma ovarii, its associated complications, and postoperative follow-up and investigations.
METHODSWe retrospectively reviewed cases of benign struma ovarii treated at KK Women's and Children's Hospital, Singapore, between January 2000 and May 2011.
RESULTSA total of 68 patients underwent surgical removal of ovarian cyst or mass (24 cystectomy, 20 salpingo-oopherectomy and 24 total hysterectomy and bilateral salpingo-oopherectomy). Of the 68 surgeries, 39 (57.4%) included intraoperative frozen section sampling or procedures for staging of ovarian malignancy. The majority (73.5%) of surgeries were laparotomies. Histology revealed benign struma ovarii in all (98.5%) but one patient. Only 7 (10.3%) patients had postoperative complications - 3 wound-related, 2 thyroid-related, 1 incisional hernia and 1 nonspecific. The mean length of hospital stay was 4.2 days. During follow-up, 45 (66.2%) patients required no additional investigations. The most common investigation done was ultrasonography (n = 18, 26.5%). While no recurrences were diagnosed histologically, two patients were subsequently found to have complex/dermoid ovarian cysts on the ipsilateral side of the previous struma ovarii on ultrasonography.
CONCLUSIONSimple surgery is recommended for patients with struma ovarii, especially if they have fertility potential. Laparoscopic surgery is the recommended approach due to its shorter recovery time and lower morbidity. Most patients do not require extended periods of follow-up or postoperative investigations.
Cystectomy ; Female ; Follow-Up Studies ; Humans ; Hysterectomy ; Laparoscopy ; Length of Stay ; Middle Aged ; Neoplasm Recurrence, Local ; surgery ; Ovarian Neoplasms ; diagnosis ; surgery ; Ovariectomy ; Ovary ; pathology ; Postoperative Period ; Retrospective Studies ; Salpingectomy ; Singapore ; Struma Ovarii ; diagnosis ; surgery
3.Improving door-to-balloon times in primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: the value of an audit-driven quality initiative.
Rabind A CHARLES ; Shiou Liang WEE ; Bernard W K KWOK ; Caren TAN ; Swee Han LIM ; Venkataraman ANANTHARAMAN ; Wasantha HEMANTHAKUMARI ; Terrance S J CHUA
Annals of the Academy of Medicine, Singapore 2008;37(7):568-572
INTRODUCTIONThe study was designed to reduce door-to-balloon times in primary percutaneous coronary intervention for patients presenting to the Emergency Department with acute ST-elevation myocardial infarction, using an audit as a quality initiative.
MATERIALS AND METHODSA multidisciplinary work group performed a pilot study over 3 months, then implemented various process and work-flow strategies to improve overall door-to-balloon times.
RESULTS AND CONCLUSIONWe developed a guideline-based, institution-specific written protocol for triaging and managing patients who present to the Emergency Department with symptoms suggestive of STEMI, resulting in shortened median door-to-balloon times from 130.5 to 109.5 minutes (P<0.001).
Angioplasty, Balloon, Coronary ; Emergency Service, Hospital ; statistics & numerical data ; utilization ; Health Care Surveys ; Humans ; Medical Audit ; Myocardial Infarction ; physiopathology ; therapy ; Pilot Projects ; Program Development ; Quality Indicators, Health Care ; Quality of Health Care ; Singapore ; Time Factors ; Triage
4.Improving access to outpatient cardiac care at the national heart centre--a partnership between specialists and primary care.
Shiou Liang WEE ; Bernard W K KWOK ; Chee Beng TAN ; Terrance S J CHUA
Annals of the Academy of Medicine, Singapore 2008;37(2):151-157
Ensuring timely access to specialist care is an important indicator of the quality of a health service. Demand for cardiology outpatient appointments has grown considerably in the last decade, leading to increased waiting time for cardiology appointments at public hospitals. This paper examines the effectiveness of past and ongoing strategies initiated by the National Heart Centre, many of which were in collaboration with SingHealth Polyclinics, documents the lessons learnt, and provides a framework for approaching this problem. Instead of a simplistic approach where institutions react to long waiting times by growing capacity to meet demand, this paper emphasises the need to focus on the final intended outcome (timely diagnosis and treatment) rather than on a single performance indicator, such as waiting time. A broad systems approach at the national level is advocated, rather than piecemeal, uncoordinated actions by individual hospitals.
Ambulatory Care Facilities
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Cardiology
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Cardiovascular Diseases
;
therapy
;
Cooperative Behavior
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Efficiency, Organizational
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Health Services Accessibility
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Health Services Needs and Demand
;
Humans
;
Primary Health Care
;
Referral and Consultation
;
trends
;
Singapore
5.Pattern and outcome of subsidised referrals to cardiology specialist outpatient clinics.
Bernard W K KWOK ; Hak Chiaw TANG ; Shiou Liang WEE ; Virginia U M TAI ; Caren G P TAN ; Terrance S J CHUA
Annals of the Academy of Medicine, Singapore 2008;37(2):103-108
INTRODUCTIONIncreasing demand for public healthcare and access to specialist care has become a major concern. Characterising the referral pattern to a national centre's cardiology specialist outpatient clinics (SOCs) and the diagnostic outcomes may be useful in formulating referral guidelines to contain rising demand.
MATERIALS AND METHODSA prospective observational followup study was conducted of all consecutive new patient referrals to the cardiology SOCs of the National Heart Centre over a 1-month period. The records of these 1224 patients were reviewed following their first visit and again after 3 months of evaluation and investigation. Patients' demographics, referral sources, indications of referral, risk factors, provisional and final diagnoses were collected. Referrals from the top 2 volume sources (government polyclinics and hospital Emergency Department) accounted for 600 referrals. These subsidised referrals formed the study group for analysis.
RESULTSThe mean age of referred patients was 56 +/- 15.2 years, with equal proportion of males and females. Most patients had known cardiac risk factors of hypertension (53.2%) and hyperlipidaemia (42.3%). Only 23% of referrals had significant cardiac abnormalities. Referrals for typical chest pain derived the highest yield whereas referrals for atypical chest pain, non-cardiac chest pain derived the lowest yield. Referrals for asymptomatic electrocardiogram (ECG) changes (except for atrial flutter/fibrillation) did not yield cardiac abnormalities. Multivariate analysis of chest pain referrals showed typical chest pain and hyperlipidaemia to be statistically significant predictors for coronary artery disease.
CONCLUSIONReferrals to cardiology outpatient specialist clinics should be based on the presence of patient symptoms, particularly that of typical chest pain. In asymptomatic patients, routine ECG screening did not appear to yield significant cardiac abnormalities.
Adult ; Aged ; Ambulatory Care Facilities ; Cardiology ; Cardiovascular Diseases ; diagnosis ; physiopathology ; Female ; Health Services Needs and Demand ; Humans ; Male ; Medicine ; Middle Aged ; Prospective Studies ; Referral and Consultation ; economics ; utilization ; Singapore ; Specialization

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