Introduction: Considering that the population density, social stress and frustrations, environmental and air pollution, and diseases directly related to unhealthy lifestyle are high, it is necessary to ensure the protection and support of public health, and to improve the quality and accessibility of localized healthcare services evenly, which in turn must meet the satisfaction of clients and professionals.
Statistical data indicates that between 2022-2023, a total of 2595 pharmacies operated in Mongolia, including 268 (10.3%) first-level pharmacies, 2178 (83.9%) second-level pharmacies, and 149 (5.7%) circulating pharmacies. In the first quarter of 2024, a total of 2916 pharmacies are active, comprising 249 (8.5%) first-level, 2531 (86.8%) second-level, and 136 (4.5%) circulating pharmacies. Based on these statistical figures, the number of pharmacies has been increasing year by year, making it necessary to study the satisfaction levels of professionals and clients. Methods: The satisfaction survey of pharmacy customers and pharmaceutical professionals was conducted using a single-stage sampling method. The sample size was calculated considering the representativeness of the population using the Surveysystem calculator and proportional allocation methods with a table for accurate estimation. Data collection was carried out between the second quarter of 2024 and the first quarter of 2025, using two types of questionnaires based on the SERVQUAL model, with five likert-scale measures, along with informed consent forms.
The survey was conducted among pharmacy staff and customers in Ulaanbaatar districts: Bayangol, Baganuur, Bagakhangai, Nalaikh, Sukhbaatar, Chingeltei, Khan-Uul, Songinokhairkhan, and Bayanzurkh, using random sampling methods. Data processing was performed with microsoft excel and spss 25.0.
A total of 1381 participants were involved, including n=997 pharmacists and n=384 customers from nine districts of Ulaanbaatar, to evaluate and analyze satisfaction levels. The findings are as follows: Among the customers who participated in the survey, 45.8% (176) were male and 54.2% (208) were female. A total of (n=384) customers took part in the study, of whom 67.7% (260) reported being satisfied with the pharmacy services the highest proportion in the dataset. Examining satisfaction by age group showed that customers under 25 years old (94) and those aged 26–35 (70) were satisfied with the services.
In the survey on job satisfaction among pharmacy professionals, 11.9% (124) of respondents were male and 83.9% (873) were female. When evaluating the job satisfaction of professionals across districts (n=997), no major differences were observed between districts. However, the proportion of respondents who reported being “Very satisfied” and “Satisfied” were relatively higher in the following districts: Bayangol at 10.3% (103), Khan-Uul at 7.9% (79), Bayanzurkh at 11.1% (111), Sukhbaatar at 7.02% (70), and Songinokhairkhan at 8.4% (84). By age group, the highest levels of job satisfaction were seen among professionals aged 26–35 (52.4%, 230) and 36–45 (55.2%, 112). Conclusion
1. Among the 384 clients involved in the study, 67.7% (n=260) were satisfied with the pharmacy services, assistance, and environment.
2. When assessing the job satisfaction of pharmacists, 77.4% (n=772) of the 997 pharmacists across 9 districts reported being confident in their career choice and “Satisfied” or “Very satisfied”.

Abstract The genus Saxifraga, one of the largest genera of the Saxifragaceae family, comprises 540 species and is distributed widely in mountainous and rocky regions, with 12 species being found in Mongolia. Saxifraga spinulosa Adams is a perennial herbaceous plant common in mainland China, Russia, and Mongolia, inhabiting stony marginal terrain. The isolated compounds from Saxifraga spinulosa were screened for DPPH radical-scavenging activity, with Trolox as a positive control (IC₅₀ 23.3 µM). All the new glucosides exhibited potent activities (IC₅₀ 19.0–72.9 µM). A crude ex- tract of S. spinulosa has been reported to display the highest DPPH radical-scavenging activity among numerous Mongolian medicinal plants, which may now be attributed, at least in part, to the presence of the new flavonoid and galloyl group-containing isolated compounds.

Introduction: The main goal of the modern national drug manufacturer is to develop highly biological active, low-side effects and no toxicity pharmaceutical products that can replace synthetic drugs with natural animal, plant and mineral raw materials. We conducted this study in aim to develop the standard of pharmacopoeia of root of Caryopteris mongolica which an antibacterial activity plant that grows in Mongolia. The study included experiments to determine the appearance of the plant, to determine its anatomical structure, to determine the quantitative analysis of pharmacognosy and to determine the microbiological analysis. Method: We defined the appearance of plant by sensory method, anatomical structure of plant by light microscopy method. And we experimented the quantitative analysis of pharmacognosy and microbiological analysis of plant according to the methodology specified in the general requirements for medicinal plant raw material of the National Pharmacopoeia of Mongolia. Conclusion As a result of the study, the appearance of plant was brown, woody thick, has many branched roots, odorless and bitter. The quantitative analysis of pharmacognosy of plant met the general requirements for medicinal plant raw material. For microbiological analysis, plant met the all requirements.

Introduction: In gallstone diseases, common bile duct stones and thickened bile could cause hepatitis or other difficulties. Therefore intraoperative cholangiography is helpful in many operations besides detecting and diagnosing the gallstones in common bile duct. Materials and Methods: Out of 266 patients who had undergone Laparoscopic Cholecystectomy surgery in GrandMed Hospital, 14 patients were found to have jaundice and cholestasis after undergoing laboratory and radiology tests. Results: These 14 patients have all undergone IOC. 7 out of 14 patients were found to have positive cholangiogram and the other 7 - negative. Biliary tract tumor and anatomic anomalies were not identified among these patients. Conclusion: Making analysis using only laboratory data is not adequate for directly detecting choledocholithiasis. IOC not only shows bile tract obstruction and determines cholestasis causes, but it also identifies the anatomy biliary tract, which is a procedure that facilitates dissection. Therefore IOCcan prevent the most serious complication of laparoscopic cholecystectomy - common bile duct injury. The sensitivity of IOC ensures the gathering of important information on time, so suggest to use it for every suspicious case.

Introduction: In gallstone diseases,common bile duct stones and thickened bilecould cause hepatitis or other difficulties.Therefore intraoperative cholangiography ishelpful in many operations besides detectingand diagnosing the gallstones in commonbile duct.Materials and Methods: Out of 266patients who had undergone LaparoscopicCholecystectomy surgery in GrandMedHospital, 14 patients were found to havejaundice and cholestasis after undergoinglaboratory and radiology tests.Results: These 14 patients have allundergone IOC. 7 out of 14 patients werefound to have positive cholangiogram andthe other 7 - negative. Biliary tract tumorand anatomic anomalies were not identifiedamong these patients.Conclusion: Making analysis usingonly laboratory data is not adequate fordirectly detecting choledocholithiasis. IOCnot only shows bile tract obstruction anddetermines cholestasis causes, but it alsoidentifies the anatomy biliary tract, whichis a procedure that facilitates dissection.Therefore IOCcan prevent the most seriouscomplication of laparoscopic cholecystectomy- common bile duct injury. The sensitivityof IOC ensures the gathering of importantinformation on time, so suggest to use it forevery suspicious case.

Introduction: Alzheimer’s disease(AD) is the most common neurodegenerative disease and characterized by memory impairment, language deterioration, cognitive dysfunction, behavioral disturbances and deficits in activities in daily living [1,2]. Acetylcholinesterase(AchE) inhibitors have been used effective treatment for AD disease targets[3]. Therefore, it is needed to isolate bioactive compounds from plants.Materials and methods: Trisma buffer pH 8.0, DTNB(5.5-dithiobis-2-nitribenzoic acid), acethylcholinesterase enzyme, acethylcholin iodide- Ach and methanol reagents were used. Plants were collected from Mongolian khangai, steppe, gobi regions. The dried plant material were extracted with methanol then evaporiated at 400C in vacu. AChE inhibitory activity was determined using the Ellman’s colorimetric method.Calculation:A10 min-A00min= Δ A Inhibition % =100x (A10 control- Δ A sample) A10control A=absorptionResults and discussion: From the 65 samples studied, which prepared from different parts of 44 plants species, Salsola passerine, Rumex pseudonatronatus, Solidago dahurica, Chelidonium majus, Anthriscus sylvestris, Linaria buriatica and Achnatherum splendens showed more effect, their inhibition percentages were 32%, 30%, 30,7%, 35,7%, 61,5%, 29,8%, 28.8% and26.6%, respectively. Out of the plants, eight extracts were not identified AChE inhibitory activity and 30 extracts showed 10-20% weak inhibition ratios. This work represents some Mongolian plants have AChE inhibitory activity.Referens:1. Marston A., Kissling J., Hostettmann K., A rapid TLC bioautographic method for the detection of acetylcholinesterase and butyrylcholinesterase inhibitors in plants.Phytochem.Anal. 13.51- 54(2002)2. Eduardo luis Konrath., Bruna Medeiros Neves et all., Investigations of the in vitro and in vivo acetylcholinesterase and antioxidant activities of tradionally used Lycopodium species from South America on alkaloid extracts. Journal of Ethnoparmacology 139(2012)58-673. Shulz V., Ginkgo extract or cholinesterase inhibitors in dementia., Phytomedicine 10(2003)74-79

Acethylcholinesterase (AChE) inhibitors have been used in the treatment of Alzheimer’s disease (AD). Currently, the only effective treatment for AD disease targets the cholinergic system using anti-cholinesterase compounds. AD is progressive, degenerative disease characterized by memory loss, language deterioration, poor judgment, impaired visuospatial skills etc. There are a few synthetic medicines, e.g. tacrine, donepezil and the natural product-based rivastigmine and galantamine to treat cognitive dysfunction and memory loss associated with AD. These approved drugs are limited in use due to their adverse side effects such as gastrointestinal disturbance and bioavailability problems. There still is great interest in fi nding better AchE inhibitors. We have screened in this study the anti-acethylcholinesterase effects of 87 samples, which prepared from different parts of 43 plant species. Methanolic extracts of nine plants, namely Patrinia rupestris, Numpaea candida, Lespedeza hedysaroides, Pachypfeurum alpinum, Leontopodium Leontopodioides, Nonea pulla, Leontopodium compestre, Gypsophilea patrinii and Abies sibirica showed potent effect, their inhibition ratios were 39.65%, 42.22%, 38.06%, 40.55%, 38.82%, 35.1%, 35.85%, 35.3 % and 53.01%, respectively. Our research shows that some Mongolian medicinal plants have anti-acetylcholinesterase activity, furthermore investigations needed to isolate pure bio-active compounds from these active plants and determine their chemical structures.

We visited Mongolia in the summer of 1999 and again in the summer of 2000, and investigated the traditional and natural medicines of this country. Mongolian traditional medicine is classified into seven categories, namely, massage, acupuncture, herbal medicine, dietary cures, aromatherapy, phlebotomy and sutra recitation. Herbal medicines, as well as acupuncture and massage, are the principal remedies. These remedies are based on Tibetan traditional medicine, which is derived from Indian traditional medicine. In both rural and urban areas, the Mongolian people use many herbs and herbal prescriptions to prevent and cure acute or chronic diseases. Important herbal plant sources, such as the Ephedra and Glycyrrhiza species, are abundant. Since the abandonment of socialism, traditional medicine has made a rapid comeback and is now a popular and important remedy in Mongolia.